Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Janet Whitley"'
Autor:
Lee Butcher, Jun-Cezar Zaldua, Jose A. Carnicero, Karl Hawkins, Janet Whitley, Rangaswamy Mothukuri, Phillip A. Evans, Keith Morris, Suresh Pillai, Jorge D. Erusalimsky
Publikováno v:
Respiratory Research, Vol 23, Iss 1, Pp 1-7 (2022)
Abstract Blood levels of the soluble receptor for advanced glycation end-products (sRAGE) are acutely elevated during the host inflammatory response to infection and predict mortality in COVID-19. However, the prognostic performance of this biomarker
Externí odkaz:
https://doaj.org/article/5b1bb484d82d41ada87a19bd1f166742
Autor:
Matthew J. Lawrence PhD, Daniel R. Obaid PhD, Ahmed Sabra PhD, Janet Whitley BA, Rhianwen Quarry MBBch, Suresh Pillai MSc, Alexander J. Chase PhD, David Smith MD, Phylip R. Williams PhD, Karl Hawkins PhD, Roger H.K. Morris PhD, Phillip A. Evans MD
Publikováno v:
Clinical and Applied Thrombosis/Hemostasis, Vol 29 (2023)
Background Unfavourable clot microstructure is associated with adverse outcomes in ST elevation myocardial infarction (STEMI). We investigated the effect of comorbidities and anti-platelet treatment on clot microstructure in STEMI patients using frac
Externí odkaz:
https://doaj.org/article/8eb367a08997456997c917b8e19aaa48
Autor:
Matthew J. Lawrence, Vanessa Evans, Janet Whitley, Suresh Pillai, Phylip R. Williams, James Coulson, Manju Krishnan, Peter Slade, Kieron Power, Roger H.K. Morris, Phillip A. Evans
Publikováno v:
Pharmacology Research & Perspectives, Vol 10, Iss 2, Pp n/a-n/a (2022)
Abstract Atrial fibrillation (AF) is a major risk factor for stroke. We aim to characterize AF patients and the effects of apixaban therapy in terms of clot microstructure using gel point analysis, a novel biomarker. Seventy‐eight patients were inc
Externí odkaz:
https://doaj.org/article/a20d7bd65b524b57863155638c0a89f5
Autor:
Suresh Pillai, Vanessa Evans, Gareth Davies, Matthew J Lawrence, Janet Whitley, Ceri E Battle, Phylip R Williams, Keith Morris, Phillip A Evans
Publikováno v:
J Intensive Care Soc
Blood for coagulation analysis can be sampled from the arterial or venous system in intensive care units (ICU). The determination of clot microstructure and strength by fractal analysis (d f) gives valuable information in a range of vascular haemosta
Autor:
Oliver Watson, Suresh Pillai, Matthew Howard, Jun-Cezar Zaldua, Janet Whitley, Brian Burgess, Matthew Lawrence, Karl Hawkins, Keith Morris, Phillip Adrian Evans
Publikováno v:
Clinical hemorheology and microcirculation. 82(2)
BACKGROUND: A significant degree of mortality and morbidity in Covid-19 is due to thromboembolic disease. Coagulopathy has been well described in critically unwell patients on ICU. There is less clear evidence regarding these changes at the time of p
Autor:
Oliver Watson, Jun-Cezar Zaldua, Suresh Pillai, Janet Whitley, Matthew Howard, Matthew Lawrence, Karl Hawkins, Keith Morris, Phillip Adrian Evans
BACKGROUND: A significant degree of mortality and morbidity in Covid-19 is through thromboembolic complications, only partially mitigated by anticoagulant therapy. Reliable markers of infection severity are not fully established. OBJECTIVES: This stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f148615f131bf240edb6ca75d67b00b
https://cronfa.swan.ac.uk/Record/cronfa63235
https://cronfa.swan.ac.uk/Record/cronfa63235
Autor:
Karl Hawkins, Keith Morris, Phillip A. Evans, K Power, C Johns, S Pillai, R. L. Williams, Vanessa Evans, Matthew Lawrence, Janet Whitley
BACKGROUND: The acute vascular disease deep vein thrombosis (DVT) requires oral anticoagulants to prevent progression. Monitoring therapeutic efficacy of direct oral anticoagulants (DOAC), including rivaroxaban, is problematic as no reliable test is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8655fa7da8635c91ffa8c1a574deb67b
https://cronfa.swan.ac.uk/Record/cronfa56606/Download/56606__19665__32820538f6b540a4afc79213a019fa82.pdf
https://cronfa.swan.ac.uk/Record/cronfa56606/Download/56606__19665__32820538f6b540a4afc79213a019fa82.pdf
Autor:
Phillip A. Evans, Janet Whitley, Suresh Pillai, Keith Morris, Jeffrey W. Stephens, Gareth Davies, Matthew Lawrence, Phylip Rhodri Williams
Publikováno v:
Clinical hemorheology and microcirculation. 77(2)
BACKGROUND: Diabetic ketoacidosis (DKA) is a medical emergency with a high mortality rate and is associated with severe metabolic acidosis and dehydration. DKA patients have an increased risk of arterial and venous thromboembolism, however little is
Autor:
Vanessa Evans, Ylva Hellsten, Michael Nyberg, Matthew Lawrence, Phillip A. Evans, Janet Whitley, R. L. Williams, Gareth Davies
Background The long term benefits of exercise on the cardiovascular status of a patient have been proven, however, their benefit/risk relationship with exercise intensity is unclear. Furthermore, many thromboembolic diseases such as myocardial infarc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d4d0c245e6eb260d827138249e0da36
https://cronfa.swan.ac.uk/Record/cronfa43363/Download/0043363-11102018144911.pdf
https://cronfa.swan.ac.uk/Record/cronfa43363/Download/0043363-11102018144911.pdf
Autor:
Yongjian Liu, Joseph A. Near, Jeffrey Freeman, Janet Whitley, Robert H. Edwards, Jessica Parsons
Publikováno v:
Journal of Neuroscience Methods. 133:191-199
Xenopus laevis oocytes were injected with synthetic mRNA coding for a rat VMAT2 mutant (rVMAT2-I483A/L484A) shown previously to be retained on the plasma membrane as a result of a presumed reduction of endocytosis. Binding of the specific VMAT inhibi