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Autor:
Deanne Guthrie, Janet Rhoades, Deanna Gage-White, Gary W. White, G.K. Matheson, Vanessa Dixon
Publikováno v:
Neuropharmacology. 28(4)
It was found that gepirone and 1-(2-pyrimidinyl)-piperazine (1-PP) increased levels of corticosterone in plasma in the intact rat. Gepirone was more potent and more efficacious than its metabolite, 1-PP. The ED50 was 6.4 μmol/kg for gepirone and 65.