Zobrazeno 1 - 10
of 148
pro vyhledávání: '"Janet R. Morrow"'
Autor:
Akanksha Patel, Didar Asik, Eric M. Snyder, Joseph A. Spernyak, Paul J. Cullen, Janet R. Morrow
Publikováno v:
Magnetochemistry, Vol 6, Iss 3, p 41 (2020)
The development of MRI probes is of interest for labeling antibiotic-resistant fungal infections based on yeast. Our work showed that yeast cells can be labeled with high-spin Fe(III) complexes to produce enhanced T2 water proton relaxation. These Fe
Externí odkaz:
https://doaj.org/article/e7bb30bf1b5341f683e84fa92e0e24ae
Autor:
Didar Asik, Rachel Smolinski, Samira M. Abozeid, Travis B. Mitchell, Steven G. Turowski, Joseph A. Spernyak, Janet R. Morrow
Publikováno v:
Molecules, Vol 25, Iss 10, p 2291 (2020)
Complexes of Fe(III) that contain a triazacyclononane (TACN) macrocycle, two pendant hydroxyl groups, and a third ancillary pendant show promise as MRI contrast agents. The ancillary group plays an important role in tuning the solution relaxivity of
Externí odkaz:
https://doaj.org/article/edaf2a4ca2834f67bb9641cc34eaf876
Autor:
John C. Pinti, Elizabeth A. Kras, Akanksha Patel, Chloe L. Schrier, Christopher S. Stoj, Janet R. Morrow
Publikováno v:
Journal of Chemical Education. 99:3752-3756
Publikováno v:
Inorganic Chemistry. 61:14487-14499
The presence of multiple oxidation and spin states of first-row transition-metal complexes facilitates the development of switchable MRI probes. Redox-responsive probes capitalize on a change in the magnetic properties of the different oxidation stat
Autor:
Gregory E, Sokolow, Matthew R, Crawley, Daniel R, Morphet, Didar, Asik, Joseph A, Spernyak, A J Robert, McGray, Timothy R, Cook, Janet R, Morrow
Publikováno v:
Inorg Chem
A metal organic polyhedron (MOP) with four paramagnetic Fe(III) centers was studied as a magnetic resonance imaging (MRI) probe. The MOP was characterized in solution by using EPR and UV-vis spectroscopies, FT-ICR mass spectrometry, and in the solid
Autor:
Gregory E. Sokolow, Matthew R. Crawley, Daniel R. Morphet, Didar Asik, Joseph A. Spernyak, A. J. Robert McGray, Timothy R. Cook, Janet R. Morrow
Publikováno v:
Inorganic Chemistry. 61:2603-2611
Publikováno v:
Accounts of chemical research. 55(10)
Contrast agents are used in approximately 40% of all magnetic resonance imaging (MRI) procedures to improve the quality of the images based on the distribution and dynamic clearance of the agent. To date, all clinically approved contrast agents are G
Publikováno v:
Encyclopedia of Inorganic and Bioinorganic Chemistry
Autor:
Eric M. Snyder, Paul J. Cullen, Alexandra E. Dilillo, Akanksha Patel, Janet R. Morrow, Didar Asik
Publikováno v:
ChemMedChem. 15:1050-1057
Yeast-derived β-glucan particles (GPs) are a class of microcarriers under development for the delivery of drugs and imaging agents to immune-system cells for theranostic approaches. However, the encapsulation of hydrophilic imaging agents in the por
Autor:
Eric M. Snyder, Gage Bateman, Steven G. Turowski, Ariel Burgio, Samira M. Abozeid, Joseph A. Spernyak, Didar Asik, Janet R. Morrow
Publikováno v:
Angewandte Chemie International Edition. 59:2414-2419
Early studies suggested that FeIII complexes cannot compete with GdIII complexes as T1 MRI contrast agents. Now it is shown that one member of a class of high-spin macrocyclic FeIII complexes produces more intense contrast in mice kidneys and liver a