Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Janet R. Bogan"'
Autor:
Martin K Childers, Janet R Bogan, Daniel J Bogan, Hansel eGreiner, Melanie eHolder, Robert eGrange, Joe N Kornegay
Publikováno v:
Frontiers in Pharmacology, Vol 2 (2012)
Calpains likely play a role in the pathogenesis of Duchenne muscular dystrophy (DMD). Accordingly, calpain inhibition may provide therapeutic benefit to DMD patients. In the present study, we sought to measure benefit from administration of a novel c
Externí odkaz:
https://doaj.org/article/1a7baa2e340b44a8b4b8f6a6c8846663
Autor:
Cynthia J. Balog-Alvarez, Mihye Ahn, Robert W. Grange, Kathryn R. Wagner, Candice Brinkmeyer-Langford, Carl Morris, Daniel J. Bogan, Martin Styner, Hongtu Zhu, Joe N. Kornegay, Leigh C. Warsing, Steven W. Cotten, Naili Liu, Jiahui Wang, Jennifer L. Dow, Janet R. Bogan, Joe Palandra, Monte S. Willis, Zheng Fan
Publikováno v:
Skeletal Muscle
Background Myostatin (Mstn) is a negative regulator of muscle growth whose inhibition promotes muscle growth and regeneration. Dystrophin-deficient mdx mice in which myostatin is knocked out or inhibited postnatally have a less severe phenotype with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::638833680d9b0f45c20b4ab1abf48c26
https://doi.org/10.1186/s13395-016-0085-7
https://doi.org/10.1186/s13395-016-0085-7
Autor:
Jiahui Wang, Kathryn R. Wagner, Joe N. Kornegay, Scott J. Schatzberg, Zheng Fan, Peter P. Nghiem, Martin K. Childers, Martin Styner, Daniel J. Bogan, James F. Howard, Janet R. Bogan, Robert W. Grange, Eric P. Hoffman, Jennifer L. Dow
Publikováno v:
Physical Medicine and Rehabilitation Clinics of North America. 23:149-172
Mutations in the dystrophin gene cause Duchenne and Becker muscular dystrophy in humans and syndromes in mice, dogs, and cats. Affected humans and dogs have progressive disease that leads primarily to muscle atrophy. Mdx mice progress through an init
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a444dde65d84b413a1ce5a457384d18d
https://doi.org/10.1016/j.pmr.2011.11.014
https://doi.org/10.1016/j.pmr.2011.11.014
Autor:
Margaret M. Sleeper, Lawrence T. Bish, Kevin J. Morine, Gretchen E. Singletary, Glenn A. Walter, Dennis J. Trafny, Caryn A. Reynolds, Krista Vandenborne, Janet R. Bogan, Jennifer Pham, H. Lee Sweeney, Joe N. Kornegay, Sean C. Forbes
Publikováno v:
Human Gene Therapy. 22:1499-1509
Duchenne muscular dystrophy (DMD) is a lethal, X-linked recessive disease affecting 1 in 3,500 newborn boys for which there is no effective treatment or cure. One novel strategy that has therapeutic potential for DMD is inhibition of myostatin, a neg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4c14c397112e5326e18467627c75226
https://doi.org/10.1089/hum.2011.102
https://doi.org/10.1089/hum.2011.102
Autor:
Juan Li, Jianbin Li, Chunping Qiao, Zhenhua Yuan, Hui Zheng, Xiao Xiao, Joe N. Kornegay, Janet R. Bogan, Cheng Zhang, Dan Bogan
Publikováno v:
Human Gene Therapy. 20:1-10
Inhibition or blockade of myostatin, a negative growth factor of skeletal muscle, enhances muscle growth and therefore is considered a promising strategy for the treatment of muscle-wasting diseases such as the muscular dystrophies. Previously, we sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae27cc9b4060bf08fe70b163087381d8
https://doi.org/10.1089/hum.2008.135
https://doi.org/10.1089/hum.2008.135
Autor:
Marie Térèse Little, Serina Gisburne, Stephen J. Tapscott, Barry J. Cooper, Christian S. Kuhr, Zejing Wang, Chiara Dell'Agnola, Joe N. Kornegay, Richard S. Lee, George E. Sale, Stephen D. Hauschka, Eustacia Zellmer, Rainer Storb, Janet R. Bogan, Ted Gooley
Publikováno v:
Blood. 104:4311-4318
Duchenne muscular dystrophy (DMD) is caused by mutations in the dystrophin gene on the X-chromosome that result in skeletal and cardiac muscle damage and premature death. Studies in mice, including the mdx mouse model of DMD, have demonstrated that c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2127ccf97a2e37033adbef95e22e0d7c
https://doi.org/10.1182/blood-2004-06-2247
https://doi.org/10.1182/blood-2004-06-2247
Publikováno v:
Neuromuscular Disorders. 13:493-500
The degree of atrophy or hypertrophy of selected pelvic limb muscles was determined in the canine homologue of Duchenne muscular dystrophy. While most muscles were atrophied, the caudal and cranial sartorius were hypertrophied. Cranial sartorius weig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::273e3cdf38ab047258f28766f429524c
https://doi.org/10.1016/s0960-8966(03)00025-7
https://doi.org/10.1016/s0960-8966(03)00025-7
Autor:
Joe N. Kornegay, Margaret J. Sullivan, Martin K. Childers, Carol S. Okamura, Daniel J. Bogan, Janet R. Bogan
Publikováno v:
American Journal of Physical Medicine & Rehabilitation. 80:175-181
Objective To test the hypothesis that differential skeletal muscle involvement, previously observed in dogs with a homologue of Duchenne muscular dystrophy, correlates with the histochemical markers of myofiber injury and regeneration. Design Evidenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85c7874fcb68ea66bd122b7ade6ff976
https://doi.org/10.1097/00002060-200103000-00004
https://doi.org/10.1097/00002060-200103000-00004
Autor:
Janet R. Bogan, Justin C. DeVanna, Joe N. Kornegay, Eleanor C. Hawkins, Daniel J. Bogan, Jennifer L. Dow
Publikováno v:
Neuromuscular disorders : NMD. 24(1)
Golden retriever muscular dystrophy (GRMD) is a well-established model of Duchenne muscular dystrophy. The value of this model would be greatly enhanced with practical tools to monitor progression of respiratory dysfunction during treatment trials. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d636ad9c568a3251baa1207ed74a5693
https://pubmed.ncbi.nlm.nih.gov/24295812
https://pubmed.ncbi.nlm.nih.gov/24295812
Autor:
Robert J. Lederman, Robert F. Hoyt, Anthony Z. Faranesh, Janet R. Bogan, Israel M. Barbash, Sylvain Cecchini, Yu Yang, Tamas Virag, Lina Li, Joe N. Kornegay, Robert M. Kotin, Luis Garcia
Publikováno v:
Gene therapy
Duchenne muscular dystrophy (DMD) cardiomyopathy patients currently have no therapeutic options. We evaluated catheter-based transendocardial delivery of a recombinant adeno-associated virus (rAAV) expressing a small nuclear U7 RNA (U7smOPT) compleme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::896a491049d38b01f4a1b999aee2c266
https://pubmed.ncbi.nlm.nih.gov/22551778
https://pubmed.ncbi.nlm.nih.gov/22551778