Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Janet Nooney"'
Autor:
Jolien Freriksen, Susan Cole, Joyce van der Heijden, Karen R Yeo, Trevor Johnson, Essam Kerwash, Marika de Hoop-Sommen, Rick Greupink, Janet Nooney, Saskia de Wildt, Ping Zhao
Publikováno v:
Gates Open Research, Vol 7 (2023)
Physiologically based pharmacokinetic (PBPK) models represent computational technology to characterize drug behavior within the context of detailed human physiology. Today, PBPK is routinely used in drug development and regulatory approval to support
Externí odkaz:
https://doaj.org/article/428afdfe2659434fa3aede8712f96746
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Pregnancy-related physiological changes can alter the absorption, distribution, metabolism and excretion of medicines which may affect the safety and efficacy of the medicines administered in pregnancy. Pharmacokinetic data can thus be instrumental i
Externí odkaz:
https://doaj.org/article/4dbe56cd39254d61acbc19a64a45954e
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 9, Iss 10, Pp 547-549 (2020)
Externí odkaz:
https://doaj.org/article/b2ee08f5d48e45fbb7ee111628fd9879
Autor:
Corinne S de Vries, Darcie Everett, Leyla Sahin, Robert Ball, Agnes Saint-Raymond, June Raine, Janet Nooney, John Clements, Wei Hua, Shannon Thor, Cosimo Zaccaria, Lynne Yao, Sandra L. Kweder
Publikováno v:
Clinical Pharmacology & Therapeutics. 110:941-945
Scientists and regulators in Europe and the United States continue to seek methods and strategies to improve knowledge on rational use of medicines for pregnant and breastfeeding populations, an important subset of women's health. Regulatory agencies
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology
CPT: Pharmacometrics & Systems Pharmacology, Vol 9, Iss 10, Pp 547-549 (2020)
CPT: Pharmacometrics & Systems Pharmacology, Vol 9, Iss 10, Pp 547-549 (2020)
It is generally recommended that use of medicines should be avoided during pregnancy, sometimes however use of a medicine is essential to safeguard the health of mother and baby. A very limited number of medicines are however specifically licensed fo
Publikováno v:
Clinical Endocrinology. 59:145-155
Millions of women are treated with hormone replacement therapy (HRT) for relief of menopausal symptoms, including vasomotor flushes and sweats for which oestrogen is uniquely and highly effective. Others may continue longer-term treatment in the hope