Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Janet M Vercammen"'
Autor:
Neel A. Mansukhani, Zheng Wang, Vera P. Shively, Megan E. Kelly, Janet M. Vercammen, Melina R. Kibbe
Publikováno v:
Artery Research, Vol 20 (2017)
Externí odkaz:
https://doaj.org/article/f197ff03095a477581ff9e099e076630
Inhibiting intimal hyperplasia in prosthetic vascular grafts via immobilized all-trans retinoic acid
Autor:
Melina R. Kibbe, Wulin Jiang, Edward Moreira Bahnson, Guillermo A. Ameer, Janet M. Vercammen, Megan E. Kelly, Banu Akar, Elaine K. Gregory, Antonio R. Webb, Robert van Lith
Publikováno v:
Journal of Controlled Release. 274:69-80
Peripheral arterial disease is a leading cause of morbidity and mortality. The most commonly utilized prosthetic material for peripheral bypass grafting is expanded polytetrafluoroethylene (ePTFE) yet it continues to exhibit poor performance from res
Autor:
Monica P. Rodriguez, Nick D. Tsihlis, Melina R. Kibbe, Megan E. Flynn, Amanda R. Schwartz, Janet M. Vercammen, Qun Jiang
Publikováno v:
Journal of Surgical Research. 202:413-421
Background Diabetic patients display aggressive restenosis after vascular interventions, likely because of proproliferative influences of hyperglycemia and hyperinsulinemia. We have shown that nitric oxide (NO) inhibits neointimal hyperplasia in type
Autor:
Samuel I. Stupp, Megan E. Flynn, Wulin Jiang, Tyson J. Moyer, Janet M. Vercammen, Qun Jiang, Melina R. Kibbe, Courtney E. Morgan, Hussein A. Kassam, Edward Moreira Bahnson
Publikováno v:
Antioxidants & Redox Signaling. 24:401-418
Aims: Cardiovascular interventions continue to fail as a result of arterial restenosis secondary to neointimal hyperplasia. We sought to develop and evaluate a systemically delivered nanostructure targeted to the site of arterial injury to prevent ne
Autor:
Megan E. Flynn, Qun Jiang, Janet M. Vercammen, Melina R. Kibbe, Amanda R. Schwartz, Edward Moreira Bahnson, Ashley K. Vavra
Publikováno v:
Free Radical Biology and Medicine. 90:272-286
Vascular interventions are associated with high failure rates from restenosis secondary to negative remodeling and neointimal hyperplasia. Periadventitial delivery of nitric oxide (NO) inhibits neointimal hyperplasia, preserving lumen patency. With t
Autor:
Charles M. Rubert Peŕez, Courtney E. Morgan, Melina R. Kibbe, Edward Moreira Bahnson, Nick D. Tsihlis, Samuel I. Stupp, Janet M. Vercammen, Qun Jiang, Wulin Jiang, Timothy A. Pritts, Amanda W. Dombrowski, Vivek S. Prakash
Publikováno v:
ACS nano. 12(11)
Autor:
Amy Chen, Melina R. Kibbe, Neel A. Mansukhani, Janet M. Vercammen, Courtney E. Morgan, Zachary M. Emond, Vinit N. Varu, Zheng Wang
Publikováno v:
The Journal of surgical research. 233
Background Current procedures to treat severe atherosclerosis are traumatic to the arterial wall and often result in restenosis due to neointimal hyperplasia. We developed a novel therapy using a specially designed double occlusion balloon catheter,
Autor:
Eric E. Kelley, Qun Jiang, Edward Moreira Bahnson, Melina R. Kibbe, Janet M. Vercammen, Nathaniel C. Koo, George E. Havelka, Nadiezhda Cantu-Medellin, Aaron Tsui
Publikováno v:
Nitric Oxide. 44:8-17
Superoxide (O2(•-)) promotes neointimal hyperplasia following arterial injury. Conversely, nitric oxide ((•)NO) inhibits neointimal hyperplasia through various cell-specific mechanisms, including redox regulation. What remains unclear is whether
Autor:
Melina R. Kibbe, Zheng Wang, Amy S. Paller, Janet M. Vercammen, Courtney E. Morgan, Molly A. Wasserman
Publikováno v:
Journal of Dermatological Science. 81:203-205
Autor:
Antonio R. Webb, Janet M. Vercammen, Melina R. Kibbe, Megan E. Flynn, Elaine K. Gregory, Guillermo A. Ameer
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 307:H1419-H1429
Oral all-trans retinoic acid (atRA) has been shown to reduce the formation of neointimal hyperplasia; however, the dose required was 30 times the chemotherapeutic dose, which already has reported side effects. As neointimal formation is a localized p