Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Janet L. Watt"'
Autor:
Ronald B. Aiken, Janet L. Watt
Publikováno v:
Northeastern Naturalist. 10:17-24
Dendronotus frondosus (Ascanius 1774) is a common inhabitant of the intertidal zone of the lower Bay of Fundy. This nudibranch experiences great daily fluctuations in physical conditions that affect all aspects of its life cycle. We examined the effe
Publikováno v:
Journal of Applied Physiology. 89:1172-1178
Bronchial hyperreactivity (BHR) is associated with the presence of airway inflammation in asthma and is seen in individuals occupationally exposed to grain dust. To better understand the relationship between BHR and pulmonary inflammation after grain
Autor:
David A. Schwartz, Gary W. Hunninghake, Michael P. Jones, Christine L. Wohlford-Lenane, Janet L. Watt, Brian C. Schutte, Linda S. Powers, J D Cowden, Joel N. Kline
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 160:297-303
Individuals exposed to inhaled endotoxin (lipopolysaccharide [LPS]) can develop airway symptomatology and exacerbations of asthma. Moreover, among those occupationally exposed to organic dusts, the progression of airflow obstruction is related to the
Autor:
Matthew W. Nonnenmann, Timothy J. Quinn, Janet L. Watt, Kathy L. Frees, John F. Trapp, David A. Schwartz
Publikováno v:
Chest. 113:505-513
Study objectives To determine the effect of glucocorticoids on grain dust-induced airflow obstruction and airway inflammation. Design Randomized controlled trial. Setting University hospital. Participants Health volunteers. Interventions Two randomiz
Publikováno v:
Chest. 111:1429-1435
Pentoxifylline (PTX) has been shown to reduce sepsis-induced neutrophil sequestration in the lung and inhibit endotoxin-mediated release of tumor necrosis factor-α (TNF-α). Previously, we have shown that endotoxin appears to be the principal agent
Publikováno v:
Chest. 109:1086-1092
To evaluate the clinical utility of nasal lavage (NL), we performed post-work shift NL on 172 grain workers and 78 postal worker control subjects. The grain worker group included a higher percentage of current smokers (25.7% vs 16.7%) and a lower per
Autor:
Stephen A. Olenchock, Timothy J. Quinn, Janet L. Watt, Peter S. Thorne, David A. Schwartz, Leon F. Burmeister, S J Yagla
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 152:603-608
To identify the role of endotoxin in grain dust-induced lung disease, we conducted a population-based, cross-sectional investigation among grain handlers and postal workers. The study subjects were selected by randomly sampling all grain facilities a
Publikováno v:
Journal of endotoxin research. 12(2)
Background: Inhalation of environmental endotoxin is important in the pathogenesis of asthma and other environmental airway diseases. Inhaled airway challenge using lipopolysaccharide in humans has been performed for over 20 years to assess the airwa
Autor:
Lakshmi Durairaj, Janet L. Watt, Joel N. Kline, Joseph Zabner, Zeinab Mohamad, Janice L. Launspach
Publikováno v:
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society. 6(1)
Background Xylitol is a 5-carbon sugar that can lower the airway surface salt concentration, thus enhancing innate immunity. We tested the safety and tolerability of aerosolized iso-osmotic xylitol in subjects with cystic fibrosis. Methods In this pi
Publikováno v:
Journal of occupational and environmental hygiene. 1(3)
A human exposure apparatus was designed to administer a gas and/or aerosol directly to the subject's face. This apparatus utilized a hood associated with a powered air-purifying respirator. The design criteria included the need to maximize subject co