Knockout of Pentraxin 3, a Downstream Target of Growth Differentiation Factor-9, Causes Female Subfertility

Autor: Martin M. Matzuk, Janet L. DeMayo, Julia A. Elvin, Heidi F. Horton, Francesco J. DeMayo, Changning Yan, Simona Varani, Michael C. Byrne

Publikováno v: Molecular Endocrinology. 16:1154-1167

The ovulatory process is tightly regulated by endocrine as well as paracrine factors. In the periovulatory period, extensive remodeling of the follicle wall occurs to allow the extrusion of the oocyte and accompanying cumulus granulosa cells. Growth

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abed5fe94d4d227b2f8a578aa7490df5
https://doi.org/10.1210/mend.16.6.0859

Contributors

Autor: Paulo A. Abrahamsohn, S. Lee Adamson, Yucel Akgul, Sruthi Alahari, Paula Amato, Selim Aractingi, Petra Clara Arck, Reut Avni, Shannon A. Bainbridge, Carla L. Bandeira, Brent M. Bany, Kalyne Bertolin, Estela Bevilacqua, Juares R. Bianco, Mallikarjun Bidarimath, Marcia C. Bizinotto, Adam Blaisdell, Brad Bolon, Alexandre Bonnin, Suzanne D. Burke, Isabella Caniggia, Amanda Carniato, Zhilin Chen, Sílvio Roberto Consonni, Miguel Constância, Wendy N. Cooper, Natália S.X. Costa, Brian J. Cox, B. Anne Croy, Maria Cecília Da Lozzo Garbelini, Aline F. Dalmorin, Wendy Dean, Karina Y. Degaki, Francesco J. DeMayo, Janet L. DeMayo, Mark Dilworth, Andrew K. Edwards, Adrian Erlebacher, Xiujun Fan, Rodolfo Favaro, Allison M. Felker, Scott A. Gerber, Marina Gertsenstein, Ciprian P. Gheorghe, Jocelyn D. Glazier, Nick Goeden, Claudia Regina Gonçalves, Ravi Goyal, Koji Hayakawa, Myriam Hemberger, Mitsuko Hirosawa, Alexander P. Hofmann, Mara S. Hoshida, Sarah M. Isaac, Shuhei Ito, Judith Janzen-Pang, Paulo Pinto Joazeiro, Kiarash Khosrotehrani, Ramakrishna Kommagani, Laura C. Kusinski, Michael B. Langford, Han Li, Patricia D.A. Lima, Eliana M.O. Lippe, Lawrence D. Longo, Aline R. Lorenzon, John P. Lydon, Stephen J. Lye, Mala Mahendroo, Terry Mayhew, Angela McDonald, Alice White McVey, Junwu Mu, Chressen Catharina Remus, Bruce D. Murphy, Coral L. Murrant, Tetsuji Nagata, Andras Nagy, Dany Nassar, Nihar R. Nayak, Michal Neeman, David N. Olivieri, Valdemar A. Paffaro, Stephen C. Pang, Annie R. Peng, Dawei Qu, Anum Rahman, Matthew T. Rätsep, Tal Raz, Monique Y. Rennie, Renata Giardini Rosa, Sandra Rugonyi, Paulo H.N. Saldiva, Ionel Sandovici, Kunio Shiota, Oksana Shynlova, Colin P. Sibley, David G. Simmons, John G. Sled, Hoon-Ki Sung, Maria M. Szwarc, Carlos E. Tadokoro, Satoshi Tanaka, Chandrakant Tayade, Olga Maria Szymanski Toledo, M. Yat Tse, Denise Tse, Mariana Matera Veras, Margeaux Wetendorf, Kathie J. Whiteley, Shintaro Yagi, Aureo T. Yamada, Ana C. Zenclussen, Yu-Qing Zhou, M. Telma Zorn

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::65af845b92c12b9df543dde1d195dc80
https://doi.org/10.1016/b978-0-12-394445-0.01002-x

Tissue- and development-specific expression of the human phenylalanine hydroxylase/chloramphenicol acetyltransferase fusion gene in transgenic mice

Autor: Savio L. C. Woo, Janet L. DeMayo, Tina M. Hahn, Milton J. Finegold, Yibin Wang, D. S. Konecki, U. Lichter-Konecki

Publikováno v: Journal of Biological Chemistry. 267:15105-15110

Human phenylalanine hydroxylase (PAH) catalyzes the conversion of L-phenylalanine to L-tyrosine. Deficiency of this enzyme results in phenylketonuria, a common genetic disorder of amino acid metabolism that causes severe mental retardation. In primat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6f6af6aea9756bf02fdcfb7bad0c328c
https://doi.org/10.1016/s0021-9258(18)42152-7

Mouse hepatocytes migrate to liver parenchyma and function indefinitely after intrasplenic transplantation

Autor: Fred D. Ledley, Frances Leland, Savio L. C. Woo, Milton J. Finegold, Sanjeev Gupta, Gretchen J. Darlington, Janet L. DeMayo, Katherine P. Ponder, Jayanta Roy Chowdhury

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America. 88(4)

One approach to gene therapy for hepatic diseases is to remove hepatocytes from an affected individual, genetically alter them in vitro, and reimplant them into a receptive locus. Although returning hepatocytes to the liver itself would be advantageo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf3cc1213ed4d98fbd887517a462e0ca
https://pubmed.ncbi.nlm.nih.gov/1899924

Tissue-Specific Regulation of Human α1-Antitrypsin Gene Expression in Transgenic Mice

Autor: Shirley M. Clift, Savio L. C. Woo, Rong-Fong Shen, Milton J. Finegold, Richard N. Sifers, Janet L. DeMayo

Publikováno v: DNA. 8:101-108

The 5'-flanking sequence of the human alpha 1-antitrypsin (AAT) gene contains multiple cis-regulatory elements, including a distal enhancer and proximal sequences essential for its transcription in cultured hepatoma cells. To understand better the pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6a27ea0c8c9ba8b2ac2c7e78cbe77e8
https://doi.org/10.1089/dna.1.1989.8.101