Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Janet L Carr"'
Autor:
Lisa B. Cronk, Janet L. Carr, Benjamin A. Salisbury, Richard S. Judson, David J. Tester, Michael J. Ackerman, Vincent P. Schulz
Publikováno v:
Heart Rhythm. 3:815-821
Background Genetic testing for congenital long QT syndrome (LQTS) has been performed in research laboratories for the past decade. Approximately 75% of patients with high clinical probability for LQTS have a mutation in one of five LQTS-causing cardi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55fad12cf250bba408cbb94597db4980
https://doi.org/10.1016/j.hrthm.2006.03.016
https://doi.org/10.1016/j.hrthm.2006.03.016
Autor:
Wendy J. Bailey, Nobuyoshi Shimizu, Steven Q. Irvine, Frank H. Ruddle, Janet L. Carr, Chris T. Amemiya, Kazuhiko Kawasaki
Publikováno v:
Journal of Experimental Zoology. 294:47-62
The sea lamprey Petromyzon marinus is among the most primitive of extant vertebrates. We are interested in the organization of its Hox gene clusters, because, as a close relative of the gnathostomes, this information would help to infer Hox cluster o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::228d207165f2eb138ebec14979d06f34
https://doi.org/10.1002/jez.10090
https://doi.org/10.1002/jez.10090
Autor:
Janet L. Carr, Frank H. Ruddle, Joseph K. Hwang, Cooduvalli S. Shashikant, Jaya Bhargava, Chi-hua Chiu, Günter P. Wagner, Chris T. Amemiya
Publikováno v:
Development Genes and Evolution. 210:105-109
The identification of cis-sequences responsible for spatiotemporal patterns of gene expression often requires the functional analysis of large genomic regions. In this study a 100-kb zebrafish Hoxa-11b-lacZ reporter gene was constructed and expressed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5de637713d6724489e81e627e18005a6
https://doi.org/10.1007/s004270050016
https://doi.org/10.1007/s004270050016
Autor:
Kevin L. Bentley, Jaya Bhargava, Janet L. Carr, Frank H. Ruddle, Hsin Juan, Cooduvalli S. Shashikant
Publikováno v:
Genomics. 62:285-288
We have developed a method to clone genomic DNA selectively into a yeast–bacterial shuttle vector, pClasper, by recombinogenic targeting in yeast. A gene-specific pClasper targeting vector was constructed with small recombinogenic ends (500 bp) der
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e8ee7cd5de6ca4901f67eb61e8c4f15
https://doi.org/10.1006/geno.1999.6000
https://doi.org/10.1006/geno.1999.6000
Autor:
Frank H. Ruddle, Chris T. Amemiya, Cooduvalli S. Shashikant, Christina Ledje, Günter P. Wagner, Chang Bae Kim, Janet L. Carr
Publikováno v:
Annals of the New York Academy of Sciences. 870:238-248
In this article, we consider the role of the Hox genes in chordate and vertebrate evolution from the viewpoints of molecular and developmental evolution. Models of Hox cluster duplication are considered with emphasis on a threefold duplication model.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::927f42d47242dd0a3b5dc5ae48f2df41
https://doi.org/10.1111/j.1749-6632.1999.tb08884.x
https://doi.org/10.1111/j.1749-6632.1999.tb08884.x
Publikováno v:
The Journal of Experimental Zoology. 280:73-85
The mammalian Hox clusters arose by duplication of a primordial cluster. The duplication of Hox clusters created redundancy within cognate groups, allowing for change in function over time. The lamprey, Petromyzon marinus, occupies an intermediate po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c64eac26bed053903b5d1a708dd93a9
https://doi.org/10.1002/(sici)1097-010x(19980101)280:1<73::aid-jez9>3.0.co
https://doi.org/10.1002/(sici)1097-010x(19980101)280:1<73::aid-jez9>3.0.co
Autor:
Guido D. Pollevick, Benjamin A. Salisbury, Michael J. Ackerman, Arthur A.M. Wilde, Janet L. Carr, David J. Tester, Jamie D. Kapplinger, Carole Harris-Kerr
Publikováno v:
Heart rhythm, 6(9), 1297-1303. Elsevier
Background Long QT syndrome (LQTS) is a potentially lethal, highly treatable cardiac channelopathy for which genetic testing has matured from discovery to translation and now clinical implementation. Objectives Here we examine the spectrum and preval
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d919bfd8dfb18c2c4240a1e735753a8f
https://pubmed.ncbi.nlm.nih.gov/19716086
https://pubmed.ncbi.nlm.nih.gov/19716086
Autor:
Chris T. Amemiya, Frank H. Ruddle, Kevin L. Bentley, Cooduvalli S. Shashikant, Jaya Bhargava, Janet L. Carr
Publikováno v:
Genomics. 56:337-339
We have developed a method to capture inserts from P1 and P1 artificial chromosome (PAC) clones into a yeast–bacteria shuttle vector by using recombinogenic targeting. We have engineered a vector, pPAC-ResQ, a derivative of pClasper, which was prev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b127f01d9637b5861dd886d67abd5427
https://doi.org/10.1006/geno.1998.5710
https://doi.org/10.1006/geno.1998.5710
Autor:
David J Tester, Benjamin A Salisbury, Janet L Carr, Carole Harris-Kerr, Carol R Reed, Michael J Ackerman
Publikováno v:
Circulation. 116
Background: Long QT Syndrome (LQTS) genetic testing has been available clinically since August 2004. In cases of bona fide LQTS, the yield of genetic testing is approximately 75%. Recently (HRS 2007), Priori and colleagues have suggested that referra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e12b248d71aaf08fff37ae509d05292
https://doi.org/10.1161/circ.116.suppl_16.ii_662-b
https://doi.org/10.1161/circ.116.suppl_16.ii_662-b
Autor:
Joaquin Santolaya, Jyh Kae Nien, Benjamin A. Salisbury, Kimberly Volkenant, Qing Lu, Roberto Romero, Ernesto Behnke, Jane M. Olson, Tinnakorn Chaiworapongsa, Guy M. Lenk, Gerard Tromp, Margarita Solari, Neeta Parimi, Katrina A.B. Goddard, Zhiying Xu, Madan Kumar Anant, Jimmy Espinoza, Gerald F. Vovis, Min Soeb Lee, Janet L. Carr, Ricardo Gomez, Helena Kuivaniemi
Publikováno v:
Human heredity. 63(1)
Pre-eclampsia (PE) affects 5–7% of pregnancies in the US, and is a leading cause of maternal death and perinatal morbidity and mortality worldwide. To identify genes with a role in PE, we conducted a large-scale association study evaluating 775 SNP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65e60a3cfe9bebe20b877ba54670a991
https://pubmed.ncbi.nlm.nih.gov/17179726
https://pubmed.ncbi.nlm.nih.gov/17179726