Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Janet Kerstin Peper"'
Autor:
Annika Nelde, Juliane Sarah Walz, Daniel Johannes Kowalewski, Heiko Schuster, Olaf-Oliver Wolz, Janet Kerstin Peper, Yamel Cardona Gloria, Anton W. Langerak, Alice F. Muggen, Rainer Claus, Irina Bonzheim, Falko Fend, Helmut Rainer Salih, Lothar Kanz, Hans-Georg Rammensee, Stefan Stevanović, Alexander N. R. Weber
Publikováno v:
OncoImmunology, Vol 6, Iss 3 (2017)
Genome sequencing has uncovered an array of recurring somatic mutations in different non-Hodgkin lymphoma (NHL) subtypes. If affecting protein-coding regions, such mutations may yield mutation-derived peptides that may be presented by HLA class I pro
Externí odkaz:
https://doaj.org/article/6fbd23161b974b24849417e491c35159
Autor:
Malte Roerden, Reinhild Klein, Jonas Rieth, Stefan Stevanovic, Ana Marcu, Tim H. Brümmendorf, Annika Nelde, Vladan Vucinic, Juliane S. Walz, Mirle Schemionek, Daniel J. Kowalewski, Jens Bauer, Dietger Niederwieser, Maren Lübke, Heiko Schuster, Leon Bichmann, Janet Kerstin Peper, Marian Christoph Neidert, Hans-Georg Rammensee, Oliver Kohlbacher, Tatjana Bilich, Melanie Märklin, Helmut R. Salih, Chih-Chiang Tsou, Lothar Kanz
Publikováno v:
Blood. 133:550-565
Antileukemia immunity plays an important role in disease control and maintenance of tyrosine kinase inhibitor (TKI)-free remission in chronic myeloid leukemia (CML). Thus, antigen-specific immunotherapy holds promise for strengthening immune control
Autor:
Janet Kerstin Peper, Annika Nelde, Daniel J. Kowalewski, Hans-Georg Rammensee, Cosima Zimmermann, Maren Lübke, Liane Bauersfeld, Anne Halenius, Oliver Kohlbacher, Juliane S. Walz, Stefanie Spalt, Hartmut Hengel, Stefan Stevanovic, Leon Bichmann, Vu Thuy Khanh Le-Trilling, Ana Marcu
Publikováno v:
The Journal of Experimental Medicine
This work demonstrates a novel strategy that enables the identification of HCMV-derived T cell epitopes by mass spectrometry. It provides a panel of novel T cell epitopes and presents evidence for their involvement in physiologic immune control of HC
Autor:
Oliver Kohlbacher, Kevin Röhle, Barbara Schmid-Horch, Stefan Stevanovic, Nico Trautwein, Daniel J. Kowalewski, Tatjana Bilich, Britta Ney, Armin Rabsteyn, Heiko Schuster, Janet Kerstin Peper, Annette Staebler, Sara Y. Brucker, T Engler, Sabine Braun, Sebastian P. Haen, Hans-Christian Bösmüller, Linus Backert, Falko Fend, Markus W. Löffler, Juliane S. Walz, Hans-Georg Rammensee, Diethelm Wallwiener, Philipp Wagner
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Despite the revolution in cancer therapy initiated by checkpoint inhibitors, durable clinical responses remain sporadic in many types of cancer, including ovarian cancer. Understanding which antigens are essentially presented by tumor ce
Autor:
Stefan Stevanovic, Heiko Schuster, Deborah Lam Pham, Hans-Georg Rammensee, Karen Greif, Hans-Christian Bösmüller, Annette Staebler, Christine Beschorner, Falko Fend, Janet Kerstin Peper, Philipp Wagner
Publikováno v:
International Journal of Gynecologic Cancer. 26:671-679
ObjectiveIncreased numbers of tumor-infiltrating lymphocytes (TILs) in high-grade serous ovarian cancer (HGSC) are associated with improved clinical outcome. Intraepithelial localization of TILs might be regulated by specific homing receptors, such a
Autor:
Stefan Stevanovic, Janet Kerstin Peper
Publikováno v:
Cancer Immunology, Immunotherapy. 64:1295-1303
The breakthrough development of immune checkpoint inhibitors as clinically effective novel therapies demonstrates the potential of cancer immunotherapy. The identification of suitable targets for specific immunotherapy, however, remains a challenging
Autor:
Marian Christoph Neidert, Patrick Roth, Luca Regli, Konstantina Kapolou, Janet Kerstin Peper, Manfred Westphal, Stefan Stevanovic, Ana Marcu, Fabian Wolpert, Günter Eisele, Daniel J. Kowalewski, Michael Weller, Reinhard Henschler, Sophie S. Wang, Hans-Georg Rammensee, Lena Katharina Freudenmann, Juliane S. Walz, Manuela Silginer, Katrin Lamszus, Linus Backert
Publikováno v:
Acta neuropathologica. 135(6)
Glioblastoma is the most frequent malignant primary brain tumor. In a hierarchical tumor model, glioblastoma stem-like cells (GSC) play a major role in tumor initiation and maintenance as well as in therapy resistance and recurrence. Thus, targeting
Publikováno v:
Cancer journal (Sudbury, Mass.). 23(2)
The interrogation of cell surface–presented immunogenic epitopes is of great importance to differentiate diseased cells in consequence to malignant transformation or viral infections. On the basis of this knowledge, next-generation immunotherapies
Respiratory syncytial virus (RSV) infection is a serious health problem in young children, immunocompromised patients, and the elderly. The development of novel prevention strategies, such as a vaccine to RSV, is a high priority. One strategy is to d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb3b2f5a17af5f204466d07c34574c7c
https://europepmc.org/articles/PMC4900221/
https://europepmc.org/articles/PMC4900221/
Autor:
Tobias Feuchtinger, Simone Kayser, Lena Hartl, Benjamin Faist, Stefan Stevanovic, Kevin M. Dennehy, Michael Neuenhahn, Patrick Günther, Gerhard Jahn, Janet Kerstin Peper, Dirk Büsch
Publikováno v:
Journal of immunotherapy (Hagerstown, Md. : 1997). 38(7)
Adenovirus infections of immunocompromised patients, particularly following allogeneic hematopoietic stem cell transplantation, are associated with morbidity and mortality. Immunotherapy by adoptive transfer of hexon-specific and penton-specific T ce