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pro vyhledávání: '"Janet Kay Epp"'
Publikováno v:
Gene. 85:293-301
The structurally related macrolide antibiotics carBomycin (Cb) and spiramycin (Sp) are produced by Streptomyces thermotolerans and Streptomyces ambofaciens, respectively. Both antibiotics contain 16-membered lactone rings to which deoxysugars are att
Publikováno v:
Gene. 53:73-83
Two plasmids (pOJ158 and pOJ159) containing DNA fragments from the carbomycin(Cb)-producing strain Streptomyces thermotolerans were identified in Streptomyces griseofuscus based on their ability to confer resistance to Cb. The Cb-resistance determina
Autor:
Janet Kay Epp, JoAnn Hoskins, George L. Long, Hansen M. Hsiung, Thomas Charles Furman, Brigitte Elisabeth Schoner, Laurane G. Mendelsohn, Dennis P. Smith, Michele C. Smith
Publikováno v:
Nature Biotechnology. 5:1047-1051
Human Insulin-like growth factor II (IGF-II) was produced in Escherichia coli as a 113 amino acid chimeric protein, LE1-Met-IGF-II consisting of 45 N-terminal amino acids from the E. coli trp leader peptide and the trpE polypeptide, and 67 C-terminal
Autor:
Janet Kay Epp, Norris E. Allen
Publikováno v:
Antimicrobial agents and chemotherapy. 13(5)
Clinically isolated strains of Staphylococcus aureus that are inducibly resistant to both erythromycin and penicillin were susceptible to a combination of the two antibiotics. The synergistic effect of the combination results from an inhibition of pe