Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Janet K. Jang"'
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 8, Iss 5, Pp 1555-1569 (2018)
Bipolar spindle assembly occurs in the absence of centrosomes in the oocytes of most organisms. In the absence of centrosomes in Drosophila oocytes, we have proposed that the kinesin 6 Subito, a MKLP-2 homolog, is required for establishing spindle bi
Externí odkaz:
https://doaj.org/article/9d44b3ae125746afa56c3b25653fed2b
Autor:
Jessica E Fellmeth, Janet K Jang, Manisha Persaud, Hannah Sturm, Neha Changela, Aashka Parikh, Kim S McKim
Publikováno v:
PLoS Genetics, Vol 19, Iss 11, p e1011066 (2023)
The centromere is an epigenetic mark that is a loading site for the kinetochore during meiosis and mitosis. This mark is characterized by the H3 variant CENP-A, known as CID in Drosophila. In Drosophila, CENP-C is critical for maintaining CID at the
Externí odkaz:
https://doaj.org/article/1e7e3263e7f1401ca9f5eff0ab0ca6f6
Autor:
Arunika Das, Amy C. Gladstein, Joanatta G Shapiro, Kim S. McKim, Zachary Sisco, Janet K. Jang
Publikováno v:
J Cell Sci
Meiosis in female oocytes lacks centrosomes, the microtubule-organizing centers. In Drosophila oocytes, meiotic spindle assembly depends on the chromosomal passenger complex (CPC). To investigate the mechanisms that regulate Aurora B activity, we exa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32113fc230ee10cc6e8381d76a5a1791
https://doi.org/10.1242/jcs.254037
https://doi.org/10.1242/jcs.254037
Meiosis in female oocytes lack centrosomes, the major microtubule-organizing center, which makes them especially vulnerable to aneuploidy. In the acentrosomal oocytes ofDrosophila, meiotic spindle assembly depends on the chromosomal passenger complex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10ebf75c09dfda906ac95522be83f440
https://doi.org/10.1101/2020.08.01.232512
https://doi.org/10.1101/2020.08.01.232512
Autor:
Tyler DeFosse, Lin-Ing Wang, Victoria F. Wagner, Rachel A. Battaglia, Kim S. McKim, Janet K. Jang
Publikováno v:
The Journal of Cell Biology
Wang et al. show that meiotic spindle assembly in Drosophila oocytes depends on the Borealin subunit of the chromosome passenger complex (CPC). Borealin does this by colocalizing with HP1, recruiting the CPC to the chromatin, and mediating movement o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bc97b494eb9404e655e785a4e4a8001
https://pubmed.ncbi.nlm.nih.gov/33836043
https://pubmed.ncbi.nlm.nih.gov/33836043
Publikováno v:
Genetics. 192:417-429
DURING meiosis in the females of many species, spindle assembly occurs in the absence of the microtubule-organizing centers called centrosomes. In the absence of centrosomes, the nature of the chromosome-based signal that recruits microtubules to pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::057befcde49b4da8392e6b82c0245d01
https://doi.org/10.1534/genetics.112.143495
https://doi.org/10.1534/genetics.112.143495
Publikováno v:
Journal of Cell Science. 119:4770-4780
Drosophila Subito is a kinesin 6 family member and ortholog of mitotic kinesin-like protein (MKLP2) in mammalian cells. Based on the previously established requirement for Subito in meiotic spindle formation and for MKLP2 in cytokinesis, we investiga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f7473e090053be323c616d20a19a2c1
https://doi.org/10.1242/jcs.03235
https://doi.org/10.1242/jcs.03235
Autor:
Jaakko Puro, Andreas Czank, Eric Kubli, Steven D. Hanes, Byron C. Williams, Vanessa L. Horner, Navjot Singh, Kim S. McKim, Mariana F. Wolfner, Janet K. Jang, Michael L. Goldberg
Publikováno v:
Current Biology. 16(14):1441-1446
SummaryActivation of mature oocytes initiates development by releasing the prior arrest of female meiosis, degrading certain maternal mRNAs while initiating the translation of others, and modifying egg coverings. In vertebrates and marine invertebrat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9942e39d8230a94e044ea860cb895690
Publikováno v:
Genetics. 169:767-781
In the pairing-site model, specialized regions on each chromosome function to establish meiotic homolog pairing. Analysis of these sites could provide insights into the mechanism used by Drosophila females to form a synaptonemal complex (SC) in the a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0485f6d68024549018f6bf6b50608103
https://doi.org/10.1534/genetics.104.035824
https://doi.org/10.1534/genetics.104.035824
Publikováno v:
Annual Review of Genetics. 36:205-232
▪ Abstract In this review, we describe the pathway for generating meiotic crossovers in Drosophila melanogaster females and how these events ensure the segregation of homologous chromosomes. As appears to be common to meiosis in most organisms, rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::750f356f2d5f20be89fecc90447ec023
https://doi.org/10.1146/annurev.genet.36.041102.113929
https://doi.org/10.1146/annurev.genet.36.041102.113929