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pro vyhledávání: '"Janet Jeyapaul"'
Autor:
Janet Jeyapaul, Anil K. Jaiswal
Publikováno v:
Biochemical Pharmacology. 59:1433-1439
gamma-Glutamylcysteine synthetase (gamma-GCS) is a rate-limiting enzyme in the de novo synthesis of glutathione, a known scavenger of electrophiles and reactive oxygen species (ROS). The gamma-GCS gene is expressed ubiquitously and induced coordinate
Autor:
Lance L. Simpson, Ren De Zhang, Robert V. Considine, Julie A. Coffield, Andrew B. Maksymowych, Janet Jeyapaul
Publikováno v:
Journal of Biological Chemistry. 269:24454-24458
Tetanus toxin is a zinc-dependent metalloendoprotease that cleaves synaptobrevin, a polypeptide found in the membranes of synaptic vesicles. This action is thought to account for toxin-induced blockade of transmitter release. However, Facchiano and L
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 87(18)
The tat protein encoded by the human immunodeficiency virus type 1 is a potent trans-activator of gene expression from the viral long terminal repeat. The domains that are essential for trans-activation, a Pro-Xaa3-Pro triad, a cysteine-rich metal-bi