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of 9
pro vyhledávání: '"Janet Hinman"'
Publikováno v:
Lipids. 39:589-593
Lipoprotein(a) [Lp(a)] represents a class of lipoprotein particles having as a protein moiety apoB-100 linked by a single disulfide bond to apolipoprotein(a) [apo(a)], a multikringle structure with a high degree of homology with plasminogen. A recogn
Publikováno v:
Analytical Biochemistry. 288:201-208
Apolipoprotein(a), apo(a), the specific multikringle glycoprotein constituent of lipoprotein(a), Lp(a), occurs in the plasma mostly bound to apoB100-containing lipoproteins but also in a free form. Often the properties of these products are determine
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1227:41-45
Human lipoprotein(a) or Lp(a) binds, like plasminogen, to lysine Sepharose. However, contrary to plasminogen in which kringles 1 and 4 have been implicated, the binding site or sites on apo(a), the specific glycoprotein of Lp(a), have not been determ
Autor:
James D. Eisenbart, Bahaa Kasawa, Janet Hinman, Gunther M. Fless, Celina Edelstein, Michael D. Sitrin, Angelo M. Scanu
Publikováno v:
Metabolism. 41:1361-1366
We have recently reported that the apolipoprotein (apo) B-100-apo(a) complex, the protein moiety of lipoprotein(a) [Lp(a)], has a high affinity for triglyceride(TG)-rich particles (TRP) and that this complex can affiliate with endogenous TG-rich lipo
Autor:
Gunther M. Fless, Kazuhiko Makino, James D. Eisenbart, Ditta Pfaffinger, Angelo M. Scanu, Janet Hinman
Publikováno v:
Arteriosclerosis and Thrombosis: A Journal of Vascular Biology. 12:424-429
Samples of human plasma having lipoprotein(a) (Lp[a]) protein levels between 5 and 15 mg/dl and a single apolipoprotein(a) (apo[a]) isoform were incubated in vitro at pH 7.7 with various concentrations (1-20 mM) of N-acetylcysteine, homocysteine, 2-m
Autor:
Claes Bergmark, Elizabeth C. Miller, Gregory M. Lipkind, Janet Hinman, Celina Edelstein, Angelo M. Scanu, Godfrey S. Getz, Sotirios Tsimikas, Ditta Pfaffinger, Joseph L. Witztum
Publikováno v:
The Journal of biological chemistry. 278(52)
Lipoprotein(a), Lp(a), an athero-thrombotic risk factor, reacts with EO6, a natural monoclonal autoantibody that recognizes the phophorylcholine (PC) group of oxidized phosphatidylcholine (oxPtdPC) either as a lipid or linked by a Schiff base to lysi
Autor:
Janet Hinman, Angelo M. Scanu
Publikováno v:
Lipids. 37(5)
Most studies on the topic have shown that statin therapy decreases plasma LDL levels but not those of lipoprotein(a) [Lp(a)]. This specificity of action, although previously noted, has not been systematically investigated. In the current study we app
Publikováno v:
Arteriosclerosis, thrombosis, and vascular biology. 21(7)
Abstract —Lipoprotein(a) [Lp(a)] represents a class of low density lipoprotein (LDL) particles that have as a protein moiety apolipoprotein B-100–linked covalently to a single molecule of apolipoprotein(a) [apo(a)], a specific multikringle protei
Publikováno v:
Fibrinolysis. 8:124