Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Janet F. FORSTNER"'
Publikováno v:
Attachment of Organisms to the Gut Mucosa ISBN: 9781351069977
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56ca9364446adb8e5aa5e782e19eec60
https://doi.org/10.1201/9781351069977-3
https://doi.org/10.1201/9781351069977-3
Publikováno v:
Infection and Immunity. 72:4188-4199
Well-differentiated cultures established from airway epithelia of patients with cystic fibrosis (CF cultures) exhibited goblet cell hyperplasia, increased secretion of mucus, and higher basal levels of interleukin-8 than similarly cultured cells from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6cfc014a5fb6c792347927b14a8c59b
https://doi.org/10.1128/iai.72.7.4188-4199.2004
https://doi.org/10.1128/iai.72.7.4188-4199.2004
Autor:
Jim Hu, Yu Hua Chow, Geraldine Kent, Umadevi S. Sajjan, Bernard Martin, David R. Koehler, A. Keith Tanswell, Colin McKerlie, Janet F. Forstner
Publikováno v:
Proceedings of the National Academy of Sciences. 100:15364-15369
We developed a helper-dependent adenoviral vector for cystic fibrosis lung gene therapy. The vector expresses cystic fibrosis transmembrane conductance regulator ( Cftr ) using control elements from cytokeratin 18 . The vector expressed properly loca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11c0c8a3389e9a24a68c656384d9b894
https://doi.org/10.1073/pnas.2436478100
https://doi.org/10.1073/pnas.2436478100
Autor:
Sameera Rahman, Rongquan Wang, Sherilyn L. Bell, Ismat A Khatri, Gongqiao Xu, Janet F. Forstner
Publikováno v:
Biochemical Journal. 373:893-900
Within the C-terminal domain of many secretory mucins is a ‘cystine knot’ (CK), which is needed for dimer formation in the endoplasmic reticulum. Previous studies indicate that in addition to an unpaired cysteine, the three intramolecular cystine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::870949367a813166b73d5dc458db8db5
https://doi.org/10.1042/bj20030096
https://doi.org/10.1042/bj20030096
Publikováno v:
Biochemical Journal. 372:263-270
In a previous study we showed, by transient expression studies in COS-1 cells, that the C-terminal domain of rat intestinal membrane mucin Muc3 was cleaved between glycine and serine within a GSIVV (one-letter) amino acid sequence during its residenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::823fac7018ba628161a729d89046c33d
https://doi.org/10.1042/bj20021333
https://doi.org/10.1042/bj20021333
Autor:
J. Thomas Lamont, K. Ramakrishnan Bhaskar, S Umadevi Sajjan, Janet F. Forstner, Ismat A Khatri, Catherine K Y Ho
Publikováno v:
Pediatric Research. 53:619-627
Cystic fibrosis (CF) patients develop chronic lung infections associated with airway obstruction by viscous and insoluble mucus secretions. Although mucus glycoproteins (mucins) are thought to be responsible for mucus plugs, other glycoconjugate comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::897848cd9ec3c2aa3facaee48f15b761
https://doi.org/10.1203/01.pdr.0000054780.11755.b9
https://doi.org/10.1203/01.pdr.0000054780.11755.b9
Publikováno v:
Microbiology. 149:961-971
Burkholderia cepacia is an opportunistic respiratory pathogen in cystic fibrosis patients. One highly transmissible and virulent clone belonging to genomovar IIIa expresses pili with unique cable morphology, which enable the bacterium to bind cytoker
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a09e7f74bb75204c0d0fd4873b8eae4c
https://doi.org/10.1099/mic.0.26176-0
https://doi.org/10.1099/mic.0.26176-0
Publikováno v:
Microbiology. 148:3477-3484
The Burkholderia cepacia complex consists of several closely related bacterial species (or genomovars) which although generally not pathogenic for healthy individuals, contribute significantly to morbidity and mortality among persons with cystic fibr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1eef5f6b56b293461ede3c9c58559e8
https://doi.org/10.1099/00221287-148-11-3477
https://doi.org/10.1099/00221287-148-11-3477
Publikováno v:
Cellular Microbiology. 4:73-86
A highly transmissible strain of Burkholderia cepacia from genomovar III carries the cable pilin gene, expresses the 22 kDa adhesin (cblA +ve/Adh +ve), binds to cytokeratin 13 (CK13) and is invasive. CK13 is expressed abundantly in the airway epithel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b6c94f7a5644b4f24b23f9158f31202
https://doi.org/10.1046/j.1462-5822.2002.00171.x
https://doi.org/10.1046/j.1462-5822.2002.00171.x
Autor:
Carola Sjolin, Brent Steer, Annie Lu, Geraldine Kent, Gregory P. Downey, Yi Jun Wu, Janet F. Forstner, Vera Cherapanov, George Thanassoulis, Colin McKerlie, Uma Sajjan, Ori D. Rotstein
Publikováno v:
Infection and Immunity. 69:5138-5150
Progressive pulmonary infection is the dominant clinical feature of cystic fibrosis (CF), but the molecular basis for this susceptibility remains incompletely understood. To study this problem, we developed a model of chronic pneumonia by repeated in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08adc9fc5fe20a9434f05e586b7b528e
https://doi.org/10.1128/iai.69.8.5138-5150.2001
https://doi.org/10.1128/iai.69.8.5138-5150.2001