Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Janet E. Holley"'
Autor:
Paul G. Weightman Potter, Sam J. Washer, Aaron R. Jeffries, Janet E. Holley, Nick J. Gutowski, Emma L. Dempster, Craig Beall
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Aims/hypothesisRecurrent hypoglycaemia (RH) is a major side-effect of intensive insulin therapy for people with diabetes. Changes in hypoglycaemia sensing by the brain contribute to the development of impaired counterregulatory responses to and aware
Externí odkaz:
https://doaj.org/article/c6c89ae5c7d94de0afbfc6a623caeb02
Autor:
Luis B. Agellon, Xing-Zhen Chen, Joanna Jung, Paul Eggleton, Allison Kraus, Qin Wenying, Miranda J. Smallwood, Marek Michalak, Myriam Pujol, Jingfeng Tang, Douglas W. Zochodne, Janet E. Holley, Tautvydas Paskevicius, Jia Newcombe, Nick Gutowski, Alison Robinson
Publikováno v:
The FASEB Journal. 34:16662-16675
We previously showed that calnexin (Canx)-deficient mice are desensitized to experimental autoimmune encephalomyelitis (EAE) induction, a model that is frequently used to study inflammatory demyelinating diseases, due to increased resistance of the b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b0516c602853b188a764fb029821f28
https://doi.org/10.1096/fj.202001539rr
https://doi.org/10.1096/fj.202001539rr
Autor:
Nicholas J. Gutowski, Eva Latorre, Janet E. Holley, Jed J. Lye, Ben P. Lee, Lorna W. Harries, Stefania Bandinelli, Luigi Ferrucci
Publikováno v:
GeroScience. 41:561-573
The accumulation of senescent cells in tissues is causally linked to the development of several age-related diseases; the removal of senescent glial cells in animal models prevents Tau accumulation and cognitive decline. Senescent cells can arise thr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f215946e0ccc35a08e041af28dec2c18
https://doi.org/10.1007/s11357-019-00100-3
https://doi.org/10.1007/s11357-019-00100-3
Autor:
Craig Beall, Sam J. Washer, Aaron R. Jeffries, Emma Dempster, Paul G. Weightman Potter, Janet E. Holley, Nick J. Gutowski
Publikováno v:
Frontiers in Endocrinology
Frontiers in Endocrinology, Vol 12 (2021)
Frontiers in Endocrinology, Vol 12 (2021)
Aims/hypothesisRecurrent hypoglycaemia (RH) is a major side-effect of intensive insulin therapy for people with diabetes. Changes in hypoglycaemia sensing by the brain contribute to the development of impaired counterregulatory responses to and aware
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6689ed3df1151a1131dc1d61708f34a3
https://pubmed.ncbi.nlm.nih.gov/34122346
https://pubmed.ncbi.nlm.nih.gov/34122346
Autor:
Lorna W Harries, Laura J McCulloch, Janet E Holley, Thomas J Rawling, Hannah J Welters, Katarina Kos
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e68253 (2013)
Aims/hypothesisWe have previously shown the implication of the multifunctional protein SPARC (Secreted protein acidic and rich in cysteine)/osteonectin in insulin resistance but potential effects on beta-cell function have not been assessed. We there
Externí odkaz:
https://doaj.org/article/120dab7d1f0b4acba4c15e4675fe6096
Autor:
Jed J, Lye, Eva, Latorre, Ben P, Lee, Stefania, Bandinelli, Janet E, Holley, Nicholas J, Gutowski, Luigi, Ferrucci, Lorna W, Harries
Publikováno v:
GeroScience
The accumulation of senescent cells in tissues is causally linked to the development of several age-related diseases; the removal of senescent glial cells in animal models prevents Tau accumulation and cognitive decline. Senescent cells can arise thr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fcf8706579737c4993d3eaadfdcfcdfb
https://pubmed.ncbi.nlm.nih.gov/31654269
https://pubmed.ncbi.nlm.nih.gov/31654269
Autor:
Paul Eggleton, Gary R. Smerdon, Janet E. Holley, Lucy Moore, Jia Newcombe, Nicholas J. Gutowski, Miranda Smallwood
Publikováno v:
Multiple Sclerosis and Related Disorders. 43:102084
Background Thousands of people with multiple sclerosis (MS) have used self-administered oxygen therapy in the UK. Clinical trials have been performed, with scant evidence that people with MS have been consulted to explore how they benefit from or how
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4881b0274d374fed5052c4330f2cd6a
https://doi.org/10.1016/j.msard.2020.102084
https://doi.org/10.1016/j.msard.2020.102084
Autor:
Christopher Power, Amber M. Paul, Jessica Wang, Alison Robinson, Allison Kraus, Jia Newcombe, Janet E. Holley, Elzbieta Dudek, Nick Gutowski, Paul Eggleton, Joanna Jung, Luis B. Agellon, Douglas W. Zochodne, Marek Michalak
Publikováno v:
JCI Insight, Vol 3, Iss 5 (2018)
In multiple sclerosis (MS), a demyelinating inflammatory disease of the CNS, and its animal model (experimental autoimmune encephalomyelitis; EAE), circulating immune cells gain access to the CNS across the blood-brain barrier to cause inflammation,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::280cacba631599351f61a46f0f0034a1
https://europepmc.org/articles/PMC5922283/
https://europepmc.org/articles/PMC5922283/
Publikováno v:
Advances in experimental medicine and biology. 958
Multiple sclerosis (MS) is normally considered a chronic inflammatory disease of the central nervous system (CNS), where T-cells breaching the blood brain barrier react against proteins of the axonal myelin sheaths, leading to focal plaques and demye
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::23d1da0e6e7ec213e7039d51dbc25070
https://pubmed.ncbi.nlm.nih.gov/28093705
https://pubmed.ncbi.nlm.nih.gov/28093705
Publikováno v:
Multiple Sclerosis: Bench to Bedside ISBN: 9783319478609
Multiple sclerosis (MS) is normally considered a chronic inflammatory disease of the central nervous system (CNS), where T-cells breaching the blood brain barrier react against proteins of the axonal myelin sheaths, leading to focal plaques and demye
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8abf345f97c53b1fc65189b2c53d8c84
https://doi.org/10.1007/978-3-319-47861-6_2
https://doi.org/10.1007/978-3-319-47861-6_2