Výsledky vyhledávání - "Janet E. B. Barber"

Engineered Aminotransferase for the Production of d-Phenylalanine Derivatives Using Biocatalytic Cascades

Autor: Nicholas J. Turner, Roberto A. Chica, Janet E. B. Barber, Fabio Parmeggiani, Jenna L. McCann, Curtis J. W. Walton

Publikováno v: Walton, C J W, Parmeggiani, F, Barber, J E B, McCann, J L, Turner, N J & Chica, R A 2017, ' Engineered Aminotransferase for the Production of d-Phenylalanine Derivatives Using Biocatalytic Cascades ', ChemCatChem, vol. 10, no. 2, pp. 470-474 . https://doi.org/10.1002/cctc.201701068

d-Phenylalanine derivatives are valuable chiral building blocks for a wide range of pharmaceuticals. Here, we developed stereoinversion and deracemization biocatalytic cascades to synthesize d-phenylalanine derivatives that contain electron-donating

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5262bc623806722bc978012c4ed047db
https://pure.manchester.ac.uk/ws/files/83280305/Walton_DAAT_Manuscript_REVISED_FINAL.docx

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Molecular phylogeny of tribe Stachydeae (Lamiaceae subfamily Lamioideae)

Autor: Günther Heubl, Yasaman Salmaki, Charlotte Lindqvist, Mika Bendiksby, Christian Bräuchler, Shahin Zarre, Olof Ryding, Janet E B Barber

Publikováno v: Molecular Phylogenetics and Evolution. 69:535-551

Although tribe Stachydeae (Lamiaceae) is considered monophyletic, relationships within the tribe are still poorly understood. The complexity of Stachydeae includes paraphyletic genera, considerable morphological plasticity, a range of ploidy levels,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a49eb3b6fbfa00c31242a73d5e1975ea
https://doi.org/10.1016/j.ympev.2013.07.024

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Continuous colorimetric screening assay for detection of d-amino acid aminotransferase mutants displaying altered substrate specificity

Autor: Janet E. B. Barber, Roberto A. Chica, Curtis J. W. Walton, Adam M. Damry, Guido F. Calderini

Publikováno v: Analytical biochemistry. 463

D-Amino acid aminotransferase (DAAT) catalyzes the synthesis of numerous d-amino acids, making it an attractive biocatalyst for the production of enantiopure d-amino acids. To bolster its biocatalytic applicability, improved variants displaying incre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b836b78b9a8c951728adcaff64e7d84e
https://pubmed.ncbi.nlm.nih.gov/24949900

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Enhancement of cisplatin cytotoxicity by disulfiram involves activating transcription factor 3

Autor: Anna, O'Brien, Janet E B, Barber, Stephanie, Reid, Nima, Niknejad, Jim, Dimitroulakos

Publikováno v: Anticancer research. 32(7)

Activating transcription factor 3 (ATF3), a stress-inducible gene, is a regulator of cisplatin-induced cytotoxicity, and enhancement of the ATF3 expression potentiates this cytotoxicity.ATF3 expression and its binding to the transcription target CHOP

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6dc913d4fec2f11059fc2ec9bbf8311f
https://pubmed.ncbi.nlm.nih.gov/22753726

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