Výsledky vyhledávání - "Janet E Williams"

Akademický článek

Breastfeeding patterns are associated with human milk microbiome composition: The Mother-Infant Microbiomes, Behavior, and Ecology Study (MIMBES).

Autor: Elizabeth A Holdsworth, Janet E Williams, Ryan M Pace, Avery A Lane, Maria Gartstein, Mark A McGuire, Michelle K McGuire, Courtney L Meehan

Publikováno v: PLoS ONE, Vol 18, Iss 8, p e0287839 (2023)

The human milk microbiome (HMM) is hypothesized to be seeded by multiple factors, including the infant oral microbiome during breastfeeding. However, it is not known whether breastfeeding patterns (e.g., frequency or total time) impact the compositio

Externí odkaz: https://doaj.org/article/be786bab78bc42c7b2c41d65389ce981

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Akademický článek

The skin microbiome facilitates adaptive tetrodotoxin production in poisonous newts

Autor: Patric M Vaelli, Kevin R Theis, Janet E Williams, Lauren A O'Connell, James A Foster, Heather L Eisthen

Publikováno v: eLife, Vol 9 (2020)

Rough-skinned newts (Taricha granulosa) use tetrodotoxin (TTX) to block voltage-gated sodium (Nav) channels as a chemical defense against predation. Interestingly, newts exhibit extreme population-level variation in toxicity attributed to a coevoluti

Externí odkaz: https://doaj.org/article/3a53a6c7fc7d494a8851e0d070ff651f

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Akademický článek

Characterization of the diversity and temporal stability of bacterial communities in human milk.

Autor: Katherine M Hunt, James A Foster, Larry J Forney, Ursel M E Schütte, Daniel L Beck, Zaid Abdo, Lawrence K Fox, Janet E Williams, Michelle K McGuire, Mark A McGuire

Publikováno v: PLoS ONE, Vol 6, Iss 6, p e21313 (2011)

Recent investigations have demonstrated that human milk contains a variety of bacterial genera; however, as of yet very little work has been done to characterize the full diversity of these milk bacterial communities and their relative stability over

Externí odkaz: https://doaj.org/article/3a86ab682ef24970ab0361e99c5b5df2

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Akademický článek

SARS-CoV-2 specific antibody trajectories in mothers and infants over two months following maternal infection

Autor: Melanie A. Martin, Monica Keith, Ryan M. Pace, Janet E. Williams, Sylvia H. Ley, Celestina Barbosa-Leiker, Beatrice Caffé, Caroline B. Smith, Amanda Kunkle, Kimberly A. Lackey, Alexandra D. Navarrete, Christina D. W. Pace, Alexandra C. Gogel, Dan T.A. Eisenberg, Bethaney D. Fehrenkamp, Mark A. McGuire, Michelle K. McGuire, Courtney L. Meehan, Eleanor Brindle

Publikováno v: Frontiers in Immunology, Vol 13 (2022)

Infants exposed to caregivers infected with SARS-CoV-2 may have heightened infection risks relative to older children due to their more intensive care and feeding needs. However, there has been limited research on COVID-19 outcomes in exposed infants

Externí odkaz: https://doaj.org/article/0f7f5bc621244c83911adcf9f28e6e10

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Akademický článek

Milk From Women Diagnosed With COVID-19 Does Not Contain SARS-CoV-2 RNA but Has Persistent Levels of SARS-CoV-2-Specific IgA Antibodies

Publikováno v: Frontiers in Immunology, Vol 12 (2021)

BackgroundLimited data are available regarding the balance of risks and benefits from human milk and/or breastfeeding during and following maternal infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).ObjectiveTo investigate wh

Externí odkaz: https://doaj.org/article/330b3090f6f4426bb6940dc8e77e39f3

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Akademický článek

Comparison of Two Approaches for the Metataxonomic Analysis of the Human Milk Microbiome

Publikováno v: Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)

Recent work has demonstrated the existence of large inter-individual and inter-population variability in the microbiota of human milk from healthy women living across variable geographical and socio-cultural settings. However, no studies have evaluat

Externí odkaz: https://doaj.org/article/d4e02e5fdc7a4457935b428b145367ce

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Akademický článek

Multipathogen Analysis of IgA and IgG Antigen Specificity for Selected Pathogens in Milk Produced by Women From Diverse Geographical Regions: The INSPIRE Study

Publikováno v: Frontiers in Immunology, Vol 11 (2021)

Breastfeeding provides defense against infectious disease during early life. The mechanisms underlying this protection are complex but likely include the vast array of immune cells and components, such as immunoglobulins, in milk. Simply characterizi

Externí odkaz: https://doaj.org/article/de55355df58b4dc59f59100a6ff601df

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Akademický článek

Characterization of SARS-CoV-2 RNA, Antibodies, and Neutralizing Capacity in Milk Produced by Women with COVID-19

Publikováno v: mBio, Vol 12, Iss 1 (2021)

Results from prior studies assaying human milk for the presence of SARS-CoV-2, the causative virus of COVID-19, have suggested milk may act as a potential vehicle for mother-to-child transmission. Most previous studies are limited because they follow

Externí odkaz: https://doaj.org/article/8d3281406bdd45b8b0d746d4e47296a5

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Comparing Top-Down Proteoform Identification: Deconvolution, PrSM Overlap, and PTM Detection

Autor: David L. Tabb, Kyowon Jeong, Karen Druart, Megan S. Gant, Kyle A. Brown, Carrie Nicora, Mowei Zhou, Sneha Couvillion, Ernesto Nakayasu, Janet E. Williams, Haley K. Peterson, Michelle K. McGuire, Mark A. McGuire, Thomas O. Metz, Julia Chamot-Rooke

Publikováno v: Journal of Proteome Research
Journal of Proteome Research, 2023, In press. ⟨10.1021/acs.jproteome.2c00673⟩

International audience; Generating top-down tandem mass spectra (MS/MS) from complex mixtures of proteoforms benefits from improvements in fractionation, separation, fragmentation, and mass analysis. The algorithms to match MS/MS to sequences have un

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c25f4304036d6681a70c9e633c36a94
https://doi.org/10.1021/acs.jproteome.2c00673

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