Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Janet Diehl"'
Autor:
Thomas J. Schall, Andrea Wang-Gillam, Deng Jun, Shichang Miao, Ferry A.L.M. Eskens, Aram F. Hezel, Ingrid M.E. Desar, David C. Linehan, Marcus Smith Noel, Johanna W. Wilmink, Janet Diehl, Frans L. G. Erdkamp, Niky Zhao, Antonia Potarca, Rajinder Singh, Jan Hillson, Stefan Sleijfer, Pirow Bekker
Publikováno v:
Journal of Clinical Oncology. 36:92-92
92 Background: The CCL2-CCR2 signaling axis may facilitate migration of myeloid derived suppressor cells to pancreatic cancer resulting in an immune suppressive tumor microenvironment. CCR2 inhibition in patients with non-metastatic pancreatic cancer
Autor:
Pirow Bekker, Antonia Potarca, Annette Bruchfeld, Patrick H. Nachman, Richard A. Lafayette, Lisa Lohr, Samir M. Parikh, Thomas J. Schall, Shichang Miao, Janet Diehl
Publikováno v:
Nephrology Dialysis Transplantation. 32:iii82-iii82
Autor:
Antonia Potarca, Stefan Sleijfer, Janet Diehl, Lisa Lohr, Rajinder Singh, David C. Linehan, Thomas J. Schall, Pirow Bekker, Shichang Miao, Ferry A.L.M. Eskens, Johanna W. Wilmink, Niky Zhao, Aram F. Hezel, Israel F. Charo, Frans L. G. Erdkamp, Marcus Smith Noel, Andrea Wang-Gillam, Deng Jun, Ingrid M.E. Desar
Publikováno v:
Journal of Clinical Oncology. 35:276-276
276 Background: CCR2 inhibition decreases tumor-associated macrophages and Treg cells, and increases CD8+ and CD4+ T cells in pancreatic tumors. Single oral doses of 150 mg CCX872-B were well tolerated in patients with pancreatic cancer. The first st