Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Janet DiPiero"'
Autor:
Yang Wu, Dieter M. Drexler, Joseph B. Santella, Thomas Brodie, Janet DiPiero, Stefan Ruepp, Umesh Hanumegowda, Brian Gemzik, Ching-Chiang Su, Evan B. Janovitz, Randy White, Michael J. Hageman, Julie Carman, John Hynes, Duohai Pan, John R. Megill
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 96:1-8
Introduction Low intrinsic solubility leading to poor oral bioavailability is a common challenge in drug discovery that can often be overcome by formulation strategies, however, it remains a potential limitation that can pose challenges for early ris
Autor:
William E. Achanzar, Holly Burr, Mark Tirmenstein, Jacqueline Calvano, Bethanne Murphy, Raja Mangipudy, Janet DiPiero, Clifford J. Hixson, Cecilia Parrula
Publikováno v:
Toxicology and Applied Pharmacology. 312:53-60
Conventional circulating biomarkers of cardiac and skeletal muscle (SKM) toxicity lack specificity and/or have a short half-life. MicroRNAs (miRNAs) are currently being assessed as biomarkers of tissue injury based on their long half-life in blood an
Autor:
Janet DiPiero, Glen B. Banks, Leslie K. Jacobsen, Nino Devidze, Denise Bounous, Linda J. Bristow, Stephen A. Stimpson, Sean C. Little, Michael K. Ahlijanian, Robert C. Gagnon, Courtney M. Smith, Mark J. Majchrzak, Alan S. Robertson, Fizal Nabbie
Publikováno v:
Neuromuscular disorders : NMD. 27(7)
Enzyme-linked and electrochemiluminescence immunoassays were developed for quantification of amino (N-) terminal fragments of the skeletal muscle protein titin (N-ter titin) and qualified for use in detection of urinary N-ter titin excretion. Urine f