Výsledky vyhledávání - "Janet C. Mayden"

Synthetic peptide inhibitors of complement serine proteases—III. Significant increase in inhibitor potency provides further support for the functional equivalence hypothesis

Autor: Janet C. Mayden, Charles Steven Schasteen, Rory F. Finn, George Irvin Glover, Sharon A. McLafferty, Lea D. Bullock, R. Paul Levine

Publikováno v: Molecular Immunology. 28:17-26

Synthetic peptides based on functionally equivalent (as defined by similar patterns of chemically equivalent amino acids) serine protease inhibitor (serpin) C-terminal sequences inhibit both classical and alternative pathways of complement activation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a782ce7d7c4f9ce28b1e8aa5210b368b
https://doi.org/10.1016/0161-5890(91)90082-u

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Synthetic peptide inhibitors of complement serine proteases--II. Effects on hemolytic activity and production of C3a and C4a

Autor: Charles Steven Schasteen, George Irvin Glover, Janet C. Mayden, Sharon A. McLafferty, R. Paul Levine, Wu-Schyong Liu, C.Y. Han

Publikováno v: Molecular immunology. 25(12)

Synthetic peptides based on the amino acid sequence at the site of cleavage of C3 by classical and alternative pathway convertases were found to be poor inhibitors of hemolysis except at concns of 1 m M and higher. Synthetic peptides of a second type

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::239373f12894783a2dce00907a7b0ed9
https://pubmed.ncbi.nlm.nih.gov/3266292

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