Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Janet C Blanks"'
Autor:
Yao Tong, Janet C. Blanks, Howard Prentice, Alfred S. Lewin, Manas R. Biswal, C. Kathleen Dorey, G. W. Smith, Ping Zhu
Publikováno v:
Journal of molecular medicine (Berlin, Germany). 96(10)
Aberrant growth of blood vessels in the choroid layer of the eye, termed choroidal neovascularization (CNV), is the pathological hallmark of exudative age-related macular degeneration (AMD), causing irreversible blindness among the elderly. Co-locali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::939e34963e4406798780b21d76a0c1a2
https://pubmed.ncbi.nlm.nih.gov/30105447
https://pubmed.ncbi.nlm.nih.gov/30105447
Autor:
Shailaja Kesaraju, Howard Prentice, Danhong Zhu, Janet C. Blanks, Diane Baronas-Lowell, Arunodoy Sur, Kasirajan Ayyanathan, David R. Hinton, Herbert Weissbach
Publikováno v:
Proceedings of the National Academy of Sciences. 111:16754-16759
The retinal pigmented epithelial (RPE) layer is one of the major ocular tissues affected by oxidative stress and is known to play an important role in the etiology of age-related macular degeneration (AMD), the major cause of blinding in the elderly.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d969dfffedfd266881fc41cb2f060fc1
https://doi.org/10.1073/pnas.1419576111
https://doi.org/10.1073/pnas.1419576111
Publikováno v:
Investigative Ophthalmology & Visual Science. 55:8044-8053
PURPOSE Muller cells, the major glial cell in the retina, play a significant role in retinal neovascularization in response to tissue hypoxia. We previously designed and tested a vector using a hypoxia-responsive domain and a glial fibrillary acidic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d50bd6c1512d11f675b0f3cf122f82a7
https://doi.org/10.1167/iovs.14-13932
https://doi.org/10.1167/iovs.14-13932
Autor:
Pawel Kreczmanski, Danielle Reis, Christoph Schmitz, C. Kathleen Dorey, Rainald Schmidt-Kastner, Roselie M.H. Diederen, Janet C. Blanks, Markus N. Preising
Publikováno v:
Experimental eye research, 89(4), 568-74. Academic Press Inc.
Wolfram syndrome 1 (WFS1, OMIM 222300), a rare genetic disorder characterized by optic nerve atrophy, deafness, diabetes insipidus and diabetes mellitus, is caused by mutations of WFS1, encoding WFS1/wolframin. Non-syndromic WFS1 variants are associa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ac17fbf3d39db34c2594563eaee1602
https://doi.org/10.1016/j.exer.2009.05.007
https://doi.org/10.1016/j.exer.2009.05.007
Publikováno v:
The Journal of Comparative Neurology. 388:47-63
Mouse retinal photoreceptor cell generation and morphogenesis take place in a well-characterized temporal sequence. Both rod and cone photoreceptor differentiation and synaptogenesis occur postnatally, but the relative timing of these events has been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d73086a821537ad5ba5545dd90b6af8c
https://doi.org/10.1002/(sici)1096-9861(19971110)388:1<47::aid-cne4>3.0.co
https://doi.org/10.1002/(sici)1096-9861(19971110)388:1<47::aid-cne4>3.0.co
Publikováno v:
Journal of Neurobiology. 32:593-612
Selective degeneration of rod photoreceptor cells in the retinal degenerative (rd) mouse prior to their complete maturation is thought to result from elevated cyclic guanosine monophosphate (cGMP) levels owing to the inherited defect in cGMP-phosphod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c5794a888d4c852aad088b4dcdcf6a6
https://doi.org/10.1002/(sici)1097-4695(19970605)32:6<593::aid-neu5>3.0.co
https://doi.org/10.1002/(sici)1097-4695(19970605)32:6<593::aid-neu5>3.0.co
Publikováno v:
Current Eye Research. 16:733-737
Purpose. A retroviral marker was used to label daughter cells arising from individual neuroblasts in the rd mouse retina, in order to investigate the hypothesis that a clonal relationship exists among degenerating photoreceptor cells. METHODS. On the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a506c7b4e3b123ff32abe204dc9c47d0
https://doi.org/10.1076/ceyr.16.7.733.5067
https://doi.org/10.1076/ceyr.16.7.733.5067
Autor:
Michael Rudisill, Mark A. Sussman, John W. McAvoy, Bradley J. Swanson, Larry Kedes, Gary E. Lyons, Janet C. Blanks
Publikováno v:
Experimental Eye Research. 63:223-232
Lens epithelial cells undergo a dramatic transformation during the process of differentiation into elongated fiber cells. The membrane-associated actin cytoskeleton is likely to play a critical role in the stabilization and maintenance of the highly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf4cc79261bd44a0f30865b55adfbef7
https://doi.org/10.1006/exer.1996.0111
https://doi.org/10.1006/exer.1996.0111
Publikováno v:
Neurobiology of Aging. 17:377-384
Morphometric analysis of the numbers of neurons in the ganglion cell layer (GCL) of the central retina (fovea/foveola/parafoveal retina) in eyes from 9 Alzheimer's disease (AD) and 11 age-matched control cases revealed an overall decrease of 25% in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea2d536f7806e4ba3fadb02460f2e1dc
https://doi.org/10.1016/0197-4580(96)00010-3
https://doi.org/10.1016/0197-4580(96)00010-3
Publikováno v:
The Journal of Comparative Neurology. 365:491-503
Somatostatin (SRIF) is a neuroactive peptide that is distributed throughout the nervous system, including the retina. This peptide has been localized to populations of amacrine cells in a variety of vertebrate species. In the rabbit retina, SRIF immu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::521b373906d50212156da083de75cda0
https://doi.org/10.1002/(sici)1096-9861(19960212)365:3<491::aid-cne11>3.0.co
https://doi.org/10.1002/(sici)1096-9861(19960212)365:3<491::aid-cne11>3.0.co