Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Janet Arras"'
Autor:
Wael El-Rifai, Abbes Belkhiri, Alexander Zaika, Jeffrey Ecsedy, Mohammed Soutto, Dunfa Peng, Janet Arras, Ahmed Katsha, Vikas Sehdev
PDF file 167K, AURKA overexpression counteracts CDDP-induced cell death in AGS cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4eb1815ed29ce7518227ad1b13f09e12
https://doi.org/10.1158/1078-0432.22450014
https://doi.org/10.1158/1078-0432.22450014
Autor:
Wael El-Rifai, Abbes Belkhiri, Alexander Zaika, Jeffrey Ecsedy, Mohammed Soutto, Dunfa Peng, Janet Arras, Ahmed Katsha, Vikas Sehdev
Purpose: Suppression of P53 (tumor protein 53) transcriptional function mediates poor therapeutic response in patients with cancer. Aurora kinase A (AURKA) and human double minute 2 (HDM2) are negative regulators of P53. Herein, we examined the role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7df565444d00ff15da4842840c7e4a73
https://doi.org/10.1158/1078-0432.c.6521820
https://doi.org/10.1158/1078-0432.c.6521820
Autor:
Wael El-Rifai, Abbes Belkhiri, Jeffrey Ecsedy, Omar M. Omar, Janet Arras, Lihong Wang, Ahmed Katsha
Purpose: Aurora kinase A (AURKA) is overexpressed in several cancer types, making it an attractive druggable target in clinical trials. In this study, we investigated the role of AURKA in regulating EIF4E, cap-dependent translation, and resistance to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::737ca2d93d0f12cf645eeacbb0cb8880
https://doi.org/10.1158/1078-0432.c.6526251
https://doi.org/10.1158/1078-0432.c.6526251
Autor:
Wael El-Rifai, Abbes Belkhiri, Alexander Zaika, Jeffrey Ecsedy, Mohammed Soutto, Dunfa Peng, Janet Arras, Ahmed Katsha, Vikas Sehdev
PDF file 1423K, AURKA regulates HDM2 through an AKT-independent mechanism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0038648ff335bcb1c3cbac486d17ff30
https://doi.org/10.1158/1078-0432.22450020.v1
https://doi.org/10.1158/1078-0432.22450020.v1
Autor:
Wael El-Rifai, Abbes Belkhiri, Alexander Zaika, Jeffrey Ecsedy, Mohammed Soutto, Dunfa Peng, Janet Arras, Ahmed Katsha, Vikas Sehdev
Supplementary Materials and Methods PDF file 37K, Supplementary Materials and Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f24e50dc6cef92ce9c55a35bb4d8f32
https://doi.org/10.1158/1078-0432.22450005
https://doi.org/10.1158/1078-0432.22450005
Autor:
Wael El-Rifai, Abbes Belkhiri, Alexander Zaika, Jeffrey Ecsedy, Mohammed Soutto, Dunfa Peng, Janet Arras, Ahmed Katsha, Vikas Sehdev
PDF file 1254K, AURKA is present in an immunocomplex with HDM2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87c8178fdd707332a1392236435f2521
https://doi.org/10.1158/1078-0432.22450011
https://doi.org/10.1158/1078-0432.22450011
Autor:
Wael El-Rifai, Abbes Belkhiri, Alexander Zaika, Jeffrey Ecsedy, Mohammed Soutto, Dunfa Peng, Janet Arras, Ahmed Katsha, Vikas Sehdev
PDF file 260K, AURKA-mediated regulation of HDM2 attenuates CDDP-induced p53 expression in GC cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a71f64465ed6703b47f0794527924462
https://doi.org/10.1158/1078-0432.22450017.v1
https://doi.org/10.1158/1078-0432.22450017.v1