Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Janet A. Sawicki"'
Publikováno v:
BioTechniques, Vol 25, Iss 5, Pp 868-875 (1998)
The ability of site-specific recombinases, like FLP and Cre, to catalyze alterations in genomic DNA is well established, whereas their application to genetic engineering strategies has been restricted because of the inability to temporally regulate t
Externí odkaz:
https://doaj.org/article/3ba410a93bf246e1bf6393dda145c151
Autor:
Jonathan R. Brody, Zhihao Zhuang, Janet A. Sawicki, Jordan M. Winter, Andrew Napper, Matthew Gehrmann, Charles J. Yeo, Agnieska K. Witkiewicz, Joseph A. Cozzitorto, Shruti Lal, Kathy Miller, Yongxing Ai, Qin Liang, Vanessa A. Talbott, Renée M. Tholey, Zoë A. Norris, Yu Peng, Richard A. Burkhart
PDF file - 59K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6065f2d773f29c29792c0beabd9cf72a
https://doi.org/10.1158/1541-7786.22509771.v1
https://doi.org/10.1158/1541-7786.22509771.v1
Autor:
Jonathan R. Brody, Mark L. Tykocinski, Rajanikanth Vadigepalli, Charles J. Yeo, Nicole Meisner-Kober, Jonathan N. Sachs, Janet A. Sawicki, Jordan M. Winter, Angie D. Lobo, Saswati N. Chand, Danielle DeCicco, Mahsa Zarei, Matthew C. Weber, Carmella Romeo
Supplemental Figure Images
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d0eb329b7ad88b1e22c594b46622ee1
https://doi.org/10.1158/1541-7786.22511716
https://doi.org/10.1158/1541-7786.22511716
Autor:
Jonathan R. Brody, Mark L. Tykocinski, Rajanikanth Vadigepalli, Charles J. Yeo, Nicole Meisner-Kober, Jonathan N. Sachs, Janet A. Sawicki, Jordan M. Winter, Angie D. Lobo, Saswati N. Chand, Danielle DeCicco, Mahsa Zarei, Matthew C. Weber, Carmella Romeo
Pancreatic ductal adenocarcinoma (PDA) is one of the most lethal cancers, in part, due to resistance to both conventional and targeted therapeutics. TRAIL directly induces apoptosis through engagement of cell surface Death Receptors (DR4 and DR5), an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34413c451ad46f9bdc5d759366dc3e0d
https://doi.org/10.1158/1541-7786.c.6540022.v1
https://doi.org/10.1158/1541-7786.c.6540022.v1
Autor:
Jonathan R. Brody, Zhihao Zhuang, Janet A. Sawicki, Jordan M. Winter, Andrew Napper, Matthew Gehrmann, Charles J. Yeo, Agnieska K. Witkiewicz, Joseph A. Cozzitorto, Shruti Lal, Kathy Miller, Yongxing Ai, Qin Liang, Vanessa A. Talbott, Renée M. Tholey, Zoë A. Norris, Yu Peng, Richard A. Burkhart
PDF file - 28K, S1. Cell growth in a high USP11 expression cell line (PL5) following siRNA treatment targeting USP11.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56828542c7b6db72d2b4961f3ceb462b
https://doi.org/10.1158/1541-7786.22509774
https://doi.org/10.1158/1541-7786.22509774
Autor:
Jonathan R. Brody, Mark L. Tykocinski, Rajanikanth Vadigepalli, Charles J. Yeo, Nicole Meisner-Kober, Jonathan N. Sachs, Janet A. Sawicki, Jordan M. Winter, Angie D. Lobo, Saswati N. Chand, Danielle DeCicco, Mahsa Zarei, Matthew C. Weber, Carmella Romeo
Supplemental Figure Legend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bd335ede44214512d502d655f8c375f
https://doi.org/10.1158/1541-7786.22511713
https://doi.org/10.1158/1541-7786.22511713
Autor:
Janet A. Sawicki, Robert C. Getts, Jonathan R. Brody, Gregory E. Gonye, Masaya Jimbo, Neelanjan Mukherjee, Kelly Rhodes, Jacquelyn Gerhart, Narumi Furuuchi, Weidan Peng, Yu-Hung Huang
Growing evidence shows that cancer cells use mRNA-binding proteins and miRNAs to posttranscriptionally regulate signaling pathways to adapt to harsh tumor microenvironments. In ovarian cancer, cytoplasmic accumulation of mRNA-binding protein HuR (ELA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56789e52be814b2ce1f3f9f82b426db7
https://doi.org/10.1158/0008-5472.c.6508052.v1
https://doi.org/10.1158/0008-5472.c.6508052.v1
Autor:
Janet A. Sawicki, Robert C. Getts, Jonathan R. Brody, Gregory E. Gonye, Masaya Jimbo, Neelanjan Mukherjee, Kelly Rhodes, Jacquelyn Gerhart, Narumi Furuuchi, Weidan Peng, Yu-Hung Huang
Supplementary Fig. S2. A. HuR mRNA levels measured by RT-PCR in A2780 transiently-transfected with siHuR and siCtrl. B. Constitutively expressed shHuR maintains inhibition of HuR expression in ovarian tumor cells. Western blots of total cell lysates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2901d8fdd5f3861e0cac4328e2039c96
https://doi.org/10.1158/0008-5472.22410710
https://doi.org/10.1158/0008-5472.22410710
Autor:
Janet A. Sawicki, Robert C. Getts, Jonathan R. Brody, Gregory E. Gonye, Masaya Jimbo, Neelanjan Mukherjee, Kelly Rhodes, Jacquelyn Gerhart, Narumi Furuuchi, Weidan Peng, Yu-Hung Huang
Supplementary Table S1. Biological function of 5 up-regulated and 6 down-regulated genes having the highest fold differences in expression in response to HuR inhibition in A2780 cells. Shaded boxes indicate transcripts to which HuR binds directly.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bbf7ad65511c8490c8202a4cefd35bc
https://doi.org/10.1158/0008-5472.22410692
https://doi.org/10.1158/0008-5472.22410692
Autor:
Jonathan R. Brody, Timothy J. Yen, Isidore Rigoutsos, Jordan M. Winter, Janet A. Sawicki, Charles J. Yeo, Zoë A. Norris, Masaya Jimbo, Carmella Romeo, Joseph A. Cozzitorto, Eric R. Londin, Vikram Bhattacharjee, Neil Beeharry, Richard A. Burkhart, Shruti Lal
AVI file - 8881KB, siRNA HuR cells progressing through mitosis after MMC treatment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9a24934e2b817906710dd2c0da88e4f
https://doi.org/10.1158/0008-5472.22401120
https://doi.org/10.1158/0008-5472.22401120