Zobrazeno 1 - 10
of 126
pro vyhledávání: '"Janet A, Gilbertson"'
Autor:
Janev Fehmi, Alexander J. Davies, Marilina Antonelou, Stephen Keddie, Sonja Pikkupeura, Luis Querol, Emilien Delmont, Andrea Cortese, Diego Franciotta, Staffan Persson, Jonathan Barratt, Ruth Pepper, Filipa Farinha, Anisur Rahman, Diana Canetti, Janet A. Gilbertson, Nigel B. Rendell, Aleksandar Radunovic, Thomas Minton, Geraint Fuller, Sinead M. Murphy, Aisling S. Carr, Mary R. Reilly, Filip Eftimov, Luuk Wieske, Charlotte E. Teunissen, Ian S. D. Roberts, Neil Ashman, Alan D. Salama, Simon Rinaldi
Publikováno v:
PLoS ONE, Vol 18, Iss 3 (2023)
Membranous glomerulonephritis (MGN) is a common cause of nephrotic syndrome in adults, mediated by glomerular antibody deposition to an increasing number of newly recognised antigens. Previous case reports have suggested an association between patien
Externí odkaz:
https://doaj.org/article/dff9589eb34c4a748b786c06b1069e74
Autor:
Ivana Slamova, Rozita Adib, Stephan Ellmerich, Michal R. Golos, Janet A. Gilbertson, Nicola Botcher, Diana Canetti, Graham W. Taylor, Nigel Rendell, Glenys A. Tennent, Guglielmo Verona, Riccardo Porcari, P. Patrizia Mangione, Julian D. Gillmore, Mark B. Pepys, Vittorio Bellotti, Philip N. Hawkins, Raya Al-Shawi, J. Paul Simons
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
ATTR amyloidosis causes heart failure through the accumulation of misfolded transthyretin in cardiac muscle. Here the authors report a mouse model of ATTR amyloidosis and demonstrate the involvement of protease activity in ATTR amyloid deposition.
Externí odkaz:
https://doaj.org/article/52dd9743e5e94eff8fed79314e07bdac
Autor:
Steven Law, Aviva Petrie, Liza Chacko, Oliver C. Cohen, Sriram Ravichandran, Janet A. Gilbertson, Dorota Rowczenio, Ashutosh Wechalekar, Ana Martinez‐Naharro, Helen J. Lachmann, Carol J. Whelan, David F. Hutt, Philip N. Hawkins, Marianna Fontana, Julian D. Gillmore
Publikováno v:
ESC Heart Failure, Vol 7, Iss 6, Pp 3942-3949 (2020)
Abstract Aims Cardiac transthyretin amyloidosis (ATTR‐CM) is a progressive and fatal condition. Prognosis can be determined at diagnosis according to the National Amyloidosis Centre (NAC) transthyretin amyloidosis (ATTR) stage. We sought to examine
Externí odkaz:
https://doaj.org/article/5ca588ecccb047eab238fa32476e0c62
Publikováno v:
BMC Nephrology, Vol 21, Iss 1, Pp 1-4 (2020)
Abstract Background Karyomegalic interstitial nephritis (KIN) is a rare hereditary cause of chronic kidney disease. It typically causes progressive renal impairment with haemoproteinuria requiring renal replacement therapy before 50 years of age. It
Externí odkaz:
https://doaj.org/article/e88a00bf59274e8c82f896f788643786
Autor:
Graham W. Taylor, Janet A. Gilbertson, Rabya Sayed, Angel Blanco, Nigel B. Rendell, Dorota Rowczenio, Tamer Rezk, P. Patrizia Mangione, Diana Canetti, Paul Bass, Philip N. Hawkins, Julian D. Gillmore
Publikováno v:
Kidney International Reports, Vol 4, Iss 7, Pp 977-986 (2019)
Introduction: Hereditary fibrinogen Aα-chain (AFib) amyloidosis is a relatively uncommon renal disease associated with a small number of pathogenic fibrinogen Aα (FibA) variants; wild-type FibA normally does not result in amyloid deposition. Proteo
Externí odkaz:
https://doaj.org/article/034578518fe347d4a2ac583d09552583
Autor:
Tamer Rezk, Janet A Gilbertson, P Patrizia Mangione, Dorota Rowczenio, Nigel B Rendell, Diana Canetti, Helen J Lachmann, Ashutosh D Wechalekar, Paul Bass, Philip N Hawkins, Vittorio Bellotti, Graham W Taylor, Julian D Gillmore
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 5, Iss 3, Pp 145-153 (2019)
Abstract The tissue diagnosis of amyloidosis and confirmation of fibril protein type, which are crucial for clinical management, have traditionally relied on Congo red (CR) staining followed by immunohistochemistry (IHC) using fibril protein specific
Externí odkaz:
https://doaj.org/article/9387814b13b64cdd87bd2fdab0cb78d9
Autor:
Dorota Rowczenio, Maria Stensland, Gustavo A. de Souza, Erik H. Strøm, Janet A. Gilbertson, Graham Taylor, Nigel Rendell, Shane Minogue, Yvonne A. Efebera, Helen J. Lachmann, Ashutosh D. Wechalekar, Philip N. Hawkins, Ketil R. Heimdal, Kristian Selvig, Inger K. Lægreid, Nathalie Demoulin, Selda Aydin, Julian D. Gillmore, Tale N. Wien
Publikováno v:
Kidney International Reports, Vol 2, Iss 3, Pp 461-469 (2017)
Fibrinogen A alpha chain amyloidosis is an autosomal dominant disease associated with mutations in the fibrinogen A alpha chain (FGA) gene, and it is the most common cause of hereditary renal amyloidosis in the UK. Patients typically present with kid
Externí odkaz:
https://doaj.org/article/eafc8316f25e41acb96af87f66ab9d68
Autor:
Rishi K. Patel, Adam Ioannou, Yousuf Razvi, Liza Chacko, Lucia Venneri, Francesco Bandera, Daniel Knight, Tushar Kotecha, Ana Martinez‐Naharro, Ambra Masi, Aldostefano Porcari, James Brown, Kiara Patel, Charlotte Manisty, James Moon, Dorota Rowczenio, Janet A. Gilbertson, Gianfranco Sinagra, Helen Lachmann, Ashutosh Wechalekar, Aviva Petrie, Carol Whelan, Philip N. Hawkins, Julian D. Gillmore, Marianna Fontana
Publikováno v:
European Journal of Heart Failure. 24:2355-2363
Aims: transthyretin amyloid cardiomyopathy (ATTR-CM) is predominantly diagnosed in men. The few available studies suggest affected women have a more favourable cardiac phenotype. We aimed to characterize sex differences among consecutive patients wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::201f1e83c40ee6974d1529cdf35a8180
https://doi.org/10.1002/ejhf.2646
https://doi.org/10.1002/ejhf.2646
Autor:
Diana Canetti, Francesca Brambilla, Nigel B. Rendell, Paola Nocerino, Janet A. Gilbertson, Dario Di Silvestre, Andrea Bergamaschi, Francesca Lavatelli, Giampaolo Merlini, Julian D. Gillmore, Vittorio Bellotti, Pierluigi Mauri, Graham W. Taylor
Publikováno v:
Molecules, Vol 26, Iss 7, p 1913 (2021)
Amyloidosis is a relatively rare human disease caused by the deposition of abnormal protein fibres in the extracellular space of various tissues, impairing their normal function. Proteomic analysis of patients’ biopsies, developed by Dogan and coll
Externí odkaz:
https://doaj.org/article/c017e28d85fb481d96668e37ce4a88b4
Autor:
Henry Somers, Ubaid Tanzim, Aldostefano Porcari, Yousuf Razvi, Tamer Rezk, Rishi Patel, Liza Chacko, Dorota Rowczenio, Janet A. Gilbertson, David F. Hutt, Philip N. Hawkins, Marianna Fontana, Julian D. Gillmore
Publikováno v:
JACC: Cardiovascular Imaging. 15:1353-1355
N/A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0467a77287bb55fd0d549088b1552b38
https://doi.org/10.1016/j.jcmg.2022.02.016
https://doi.org/10.1016/j.jcmg.2022.02.016