Optimising the diagnostic accuracy of First post-contrAst SubtracTed breast MRI (FAST MRI) through interpretation-training: a multicentre e-learning study, mapping the learning curve of NHS Breast Screening Programme (NHSBSP) mammogram readers using an enriched dataset

Autor: Lyn I. Jones, Andrea Marshall, Rebecca Geach, Premkumar Elangovan, Elizabeth O’Flynn, Tony Timlin, Sadie McKeown-Keegan, Janice Rose, Sarah Vinnicombe, Sian Taylor-Phillips, Mark Halling-Brown, Janet A. Dunn, the FAST MRI Study Group

Publikováno v: Breast Cancer Research, Vol 26, Iss 1, Pp 1-15 (2024)

Abstract Background Abbreviated breast MRI (FAST MRI) is being introduced into clinical practice to screen women with mammographically dense breasts or with a personal history of breast cancer. This study aimed to optimise diagnostic accuracy through

Externí odkaz: https://doaj.org/article/ff2a77409ae54a32b4f354fa098c0d03

ATNEC – Patient Experience Sub-Study (IRSCTN: 36585784): What Patients Think About Taking Part In Breast Cancer Treatment De-Escalation Trials?

Autor: Janet A. Dunn, Sophie Gasson, Sophie Nicholls, Jan Rose, Helen Teresa Edwards, Andrea Marshall, Natalie Hammonds, Beatrix Elsberger, Amit Goyal

Publikováno v: Breast, Vol 68, Iss , Pp 241-242 (2023)

Externí odkaz: https://doaj.org/article/6359ef9646734085bde90de382b811b6

A network analysis to identify mediators of germline-driven differences in breast cancer prognosis

Autor: Maria Escala-Garcia, Jean Abraham, Irene L. Andrulis, Hoda Anton-Culver, Volker Arndt, Alan Ashworth, Paul L. Auer, Päivi Auvinen, Matthias W. Beckmann, Jonathan Beesley, Sabine Behrens, Javier Benitez, Marina Bermisheva, Carl Blomqvist, William Blot, Natalia V. Bogdanova, Stig E. Bojesen, Manjeet K. Bolla, Anne-Lise Børresen-Dale, Hiltrud Brauch, Hermann Brenner, Sara Y. Brucker, Barbara Burwinkel, Carlos Caldas, Federico Canzian, Jenny Chang-Claude, Stephen J. Chanock, Suet-Feung Chin, Christine L. Clarke, Fergus J. Couch, Angela Cox, Simon S. Cross, Kamila Czene, Mary B. Daly, Joe Dennis, Peter Devilee, Janet A. Dunn, Alison M. Dunning, Miriam Dwek, Helena M. Earl, Diana M. Eccles, A. Heather Eliassen, Carolina Ellberg, D. Gareth Evans, Peter A. Fasching, Jonine Figueroa, Henrik Flyger, Manuela Gago-Dominguez, Susan M. Gapstur, Montserrat García-Closas, José A. García-Sáenz, Mia M. Gaudet, Angela George, Graham G. Giles, David E. Goldgar, Anna González-Neira, Mervi Grip, Pascal Guénel, Qi Guo, Christopher A. Haiman, Niclas Håkansson, Ute Hamann, Patricia A. Harrington, Louise Hiller, Maartje J. Hooning, John L. Hopper, Anthony Howell, Chiun-Sheng Huang, Guanmengqian Huang, David J. Hunter, Anna Jakubowska, Esther M. John, Rudolf Kaaks, Pooja Middha Kapoor, Renske Keeman, Cari M. Kitahara, Linetta B. Koppert, Peter Kraft, Vessela N. Kristensen, Diether Lambrechts, Loic Le Marchand, Flavio Lejbkowicz, Annika Lindblom, Jan Lubiński, Arto Mannermaa, Mehdi Manoochehri, Siranoush Manoukian, Sara Margolin, Maria Elena Martinez, Tabea Maurer, Dimitrios Mavroudis, Alfons Meindl, Roger L. Milne, Anna Marie Mulligan, Susan L. Neuhausen, Heli Nevanlinna, William G. Newman, Andrew F. Olshan, Janet E. Olson, Håkan Olsson, Nick Orr, Paolo Peterlongo, Christos Petridis, Ross L. Prentice, Nadege Presneau, Kevin Punie, Dhanya Ramachandran, Gad Rennert, Atocha Romero, Mythily Sachchithananthan, Emmanouil Saloustros, Elinor J. Sawyer, Rita K. Schmutzler, Lukas Schwentner, Christopher Scott, Jacques Simard, Christof Sohn, Melissa C. Southey, Anthony J. Swerdlow, Rulla M. Tamimi, William J. Tapper, Manuel R. Teixeira, Mary Beth Terry, Heather Thorne, Rob A. E. M. Tollenaar, Ian Tomlinson, Melissa A. Troester, Thérèse Truong, Clare Turnbull, Celine M. Vachon, Lizet E. van der Kolk, Qin Wang, Robert Winqvist, Alicja Wolk, Xiaohong R. Yang, Argyrios Ziogas, Paul D. P. Pharoah, Per Hall, Lodewyk F. A. Wessels, Georgia Chenevix-Trench, Gary D. Bader, Thilo Dörk, Douglas F. Easton, Sander Canisius, Marjanka K. Schmidt

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)

In breast cancer the contribution of different genetic variants to disease heritability is complex and not fully understood. Here, the authors present a network-based analysis in 84,567 patients studying ~7.3 million variants, identifying gene module

Externí odkaz: https://doaj.org/article/66f84cb0c160487f94b95e22db3c3093

Abstract OT3-32-01: OPTIMA, a prospective randomized trial to validate the clinical utility and cost-effectiveness of gene expression test-directed chemotherapy decisions in high clinical risk early breast cancer

Autor: Robert Stein, Andreas Makris, Iain Macpherson, Luke Hughes-Davies, Andrea Marshall, Georgina Dotchin, David A. Cameron, Belinda E. Kiely, Caroline Wilson, Anne Armstrong, Helena M. Earl, Christopher J. Poole, Janice Tsang, Bjørn Naume, Daniel Rea, Hege Ohnstad, Peter S. Hall, Stuart A. McIntosh, Bethany Shinkins, Christopher McCabe, Adrienne Morgan, John MS Bartlett, Janet A. Dunn

Publikováno v: Cancer Research. 83:OT3-32

Background: Multi-parameter tumor gene expression assays (MPAs) are used to estimate individual patient risk and guide chemotherapy use in hormone-sensitive, HER2-negative early breast cancer. The TAILORx trial supports MPA use in a node-negative pop

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4608f40c8058d8e5d8f14823e19e5775
https://doi.org/10.1158/1538-7445.sabcs22-ot3-32-01

Stratifying risk of infection and response to therapy in patients with myeloma: a prognostic study

Autor: Ilaria J Chicca, Jennifer LJ Heaney, Gulnaz Iqbal, Janet A Dunn, Stella Bowcock, Tim Planche, Guy Pratt, Kwee Yong, Eric Low, Jill Wood, Kerry Raynes, Helen Higgins, Mark T Drayson

Publikováno v: Efficacy and Mechanism Evaluation, Vol 7, Iss 10 (2020)

Background: Multiple myeloma is a cancer of plasma cells that is associated with severe immunodeficiency and increased numbers of bacterial infections. The Tackling Early Morbidity and Mortality in Myeloma (TEAMM) trial assessed the use of prophylact

Externí odkaz: https://doaj.org/article/112110a22ca74a9baedf5fd46e42bff3