Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Janet Quinn"'
Autor:
Matthew C. Fisher, Fiona Burnett, Clare Chandler, Neil A. R. Gow, Sarah Gurr, Alwyn Hart, Alison Holmes, Robin C. May, Janet Quinn, Tarek Soliman, Nicholas J. Talbot, Helen M. West, Jon S. West, P. Lewis White, Michael Bromley, Darius Armstrong-James
Publikováno v:
npj Antimicrobials and Resistance, Vol 2, Iss 1, Pp 1-10 (2024)
Abstract The emergence of fungal antimicrobial resistance—fAMR—is having a growing impact on human and animal health, and food security. This roadmap charts inter-related actions that will enhance our ability to mitigate the risk of fAMR. As huma
Externí odkaz:
https://doaj.org/article/60cce6a05e55464cad19c587a71c4e35
Autor:
Yasmin Ahmed, Mélanie A. C. Ikeh, Donna M. MacCallum, Alison M. Day, Kevin Waldron, Janet Quinn
Publikováno v:
mBio, Vol 13, Iss 3 (2022)
ABSTRACT The ability of pathogenic fungi to obtain essential nutrients from the host is vital for virulence. In Candida albicans, acquisition of the macronutrient phosphate is regulated by the Pho4 transcription factor and is important for both virul
Externí odkaz:
https://doaj.org/article/705e6bf7868e48a98baa465733475fa2
Autor:
Louisa J. Stewart, YoungJin Hong, Isabel R. Holmes, Samantha J. Firth, Yasmin Ahmed, Janet Quinn, Yazmin Santos, Steven L. Cobb, Nicholas S. Jakubovics, Karrera Y. Djoko
Publikováno v:
ACS Infectious Diseases, 2023, Vol.9(3), pp.631-642 [Peer Reviewed Journal]
Histatin-5 (Hst5) is a member of the histatin superfamily of cationic, His-rich, Zn(II)-binding peptides in human saliva. Hst5 displays antimicrobial activity against fungal and bacterial pathogens, often in a Zn(II)-dependent manner. In contrast, he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39517368ce8ed6495bbf8697118c0a32
https://doi.org/10.1021/acsinfecdis.2c00578
https://doi.org/10.1021/acsinfecdis.2c00578
Autor:
Alison M. Day, Janet Quinn
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 9 (2019)
The ability of fungal pathogens to survive hostile environments within the host depends on rapid and robust stress responses. Stress-activated protein kinase (SAPK) pathways are conserved MAPK signaling modules that promote stress adaptation in all e
Externí odkaz:
https://doaj.org/article/0af693e89da74f2bb2ce74bc88d008b3
The IV international symposium on fungal stress and the XIII international fungal biology conference
Autor:
Alene Alder-Rangel, Alexandre Melo Bailão, Alfredo Herrera-Estrella, Amanda E.A. Rangel, Attila Gácser, Audrey P. Gasch, Claudia B.L. Campos, Christina Peters, Francine Camelim, Fulvia Verde, Geoffrey Michael Gadd, Gerhard Braus, Iris Eisermann, Janet Quinn, Jean-Paul Latgé, Jesus Aguirre, Joan W. Bennett, Joseph Heitman, Joshua D. Nosanchuk, Laila P. Partida-Martínez, Martine Bassilana, Mavis A. Acheampong, Meritxell Riquelme, Michael Feldbrügge, Nancy P. Keller, Nemat O. Keyhani, Nina Gunde-Cimerman, Raquel Nascimento, Robert A. Arkowitz, Rosa Reyna Mouriño-Pérez, Sehar Afshan Naz, Simon V. Avery, Thiago Olitta Basso, Ulrich Terpitz, Xiaorong Lin, Drauzio E.N. Rangel
Publikováno v:
Fungal Biology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9c13a03295c93703c61f60686535347
https://doi.org/10.1016/j.funbio.2023.04.006
https://doi.org/10.1016/j.funbio.2023.04.006
Publikováno v:
mSphere, Vol 3, Iss 5 (2018)
ABSTRACT Candida auris has recently emerged as an important, multidrug-resistant fungal pathogen of humans. Comparative studies indicate that despite high levels of genetic divergence, C. auris is as virulent as the most pathogenic member of the genu
Externí odkaz:
https://doaj.org/article/b65f9f3705c24e72856d0a7382943bae
Autor:
Carmen Herrero-de-Dios, Alison M. Day, Anna T. Tillmann, Stavroula L. Kastora, David Stead, Paula S. Salgado, Janet Quinn, Alistair J. P. Brown
Publikováno v:
mBio, Vol 9, Iss 2 (2018)
ABSTRACT In all eukaryotic kingdoms, mitogen-activated protein kinases (MAPKs) play critical roles in cellular responses to environmental cues. These MAPKs are activated by phosphorylation at highly conserved threonine and tyrosine residues in respon
Externí odkaz:
https://doaj.org/article/f5b73d7ef4194195a32a24d030a681c5
Autor:
Alessandra da Silva Dantas, Alison Day, Mélanie Ikeh, Iaroslava Kos, Beatrice Achan, Janet Quinn
Publikováno v:
Biomolecules, Vol 5, Iss 1, Pp 142-165 (2015)
Candida albicans is a major fungal pathogen of humans, causing approximately 400,000 life-threatening systemic infections world-wide each year in severely immunocompromised patients. An important fungicidal mechanism employed by innate immune cells i
Externí odkaz:
https://doaj.org/article/f36108456d2d408785d749729a937c1c
Autor:
Arnab Pradhan, Carmen Herrero-de-Dios, Rodrigo Belmonte, Susan Budge, Angela Lopez Garcia, Aljona Kolmogorova, Keunsook K Lee, Brennan D Martin, Antonio Ribeiro, Attila Bebes, Raif Yuecel, Neil A R Gow, Carol A Munro, Donna M MacCallum, Janet Quinn, Alistair J P Brown
Publikováno v:
PLoS Pathogens, Vol 13, Iss 5, p e1006405 (2017)
Most fungal pathogens of humans display robust protective oxidative stress responses that contribute to their pathogenicity. The induction of enzymes that detoxify reactive oxygen species (ROS) is an essential component of these responses. We showed
Externí odkaz:
https://doaj.org/article/0bcccfd3be4c4b918c36e51dafd68ae0
Autor:
Alison M Day, Deborah A Smith, Mélanie A C Ikeh, Mohammed Haider, Carmen M Herrero-de-Dios, Alistair J P Brown, Brian A Morgan, Lars P Erwig, Donna M MacCallum, Janet Quinn
Publikováno v:
PLoS Pathogens, Vol 13, Iss 1, p e1006131 (2017)
The Ypd1 phosphorelay protein is a central constituent of fungal two-component signal transduction pathways. Inhibition of Ypd1 in Saccharomyces cerevisiae and Cryptococcus neoformans is lethal due to the sustained activation of the 'p38-related' Hog
Externí odkaz:
https://doaj.org/article/8363b7374d17493281fa75d5ffc25161