Zobrazeno 1 - 10
of 161
pro vyhledávání: '"Janet, Graham"'
Autor:
Kathryn A. F. Pennel, Phimmada Hatthakarnkul, Colin S. Wood, Guang-Yu Lian, Sara S. F. Al-Badran, Jean A. Quinn, Assya Legrini, Jitwadee Inthagard, Peter G. Alexander, Hester van Wyk, Ahmad Kurniawan, Umar Hashmi, Michael A. Gillespie, Megan Mills, Aula Ammar, Jennifer Hay, Ditte Andersen, Colin Nixon, Selma Rebus, David K. Chang, Caroline Kelly, Andrea Harkin, Janet Graham, David Church, Ian Tomlinson, Mark Saunders, Tim Iveson, Tamsin R. M. Lannagan, Rene Jackstadt, Noori Maka, Paul G. Horgan, Campbell S. D. Roxburgh, Owen J. Sansom, Donald C. McMillan, Colin W. Steele, Nigel B. Jamieson, James H. Park, Antonia K. Roseweir, Joanne Edwards
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-20 (2024)
Abstract Colorectal cancer (CRC) is a heterogenous malignancy underpinned by dysregulation of cellular signaling pathways. Previous literature has implicated aberrant JAK/STAT3 signal transduction in the development and progression of solid tumors. I
Externí odkaz:
https://doaj.org/article/3b63169b435447a19a5fb490ee037279
Autor:
Louise C Brown, David Fisher, Richard Adams, Jenny Seligmann, Matthew Seymour, Richard Kaplan, Susan D Richman, Philip Quirke, Rachel Butler, Helen Roberts, Janet Graham, Richard H Wilson, Timothy S Maughan
Publikováno v:
Efficacy and Mechanism Evaluation, Vol 9, Iss 9 (2022)
Background: Complex trials with innovative designs are becoming increasingly common and offer the potential to improve patient outcomes in a shorter time frame. There is evidence that patients with colorectal cancer fall into different subgroups with
Externí odkaz:
https://doaj.org/article/a710ce8c7ebb4534b2145ccccfea160e
Publikováno v:
Journal of Immunotherapy and Precision Oncology, Pp 86-104 (2021)
The treatment of locally advanced rectal cancer (LARC) has seen major advances over the past 3 decades, with multimodality treatment now standard of care. Combining surgical resection with radiotherapy and/or chemotherapy can reduce local recurrence
Externí odkaz:
https://doaj.org/article/aed1189cb21c47c9a81231b46b39a839
Autor:
Antonia K Roseweir, James H Park, Sanne ten Hoorn, Arfon GMT Powell, Susan Aherne, Campbell SD Roxburgh, Donald C McMillan, Paul G Horgan, Elizabeth Ryan, Kieran Sheahan, Louis Vermeulen, James Paul, Andrea Harkin, Janet Graham, Owen Sansom, David N Church, Ian Tomlinson, Mark Saunders, Tim J Iveson, Joanne Edwards
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 6, Iss 4, Pp 283-296 (2020)
Abstract Histological ‘phenotypic subtypes’ that classify patients into four groups (immune, canonical, latent and stromal) have previously been demonstrated to stratify survival in a stage I–III colorectal cancer (CRC) pilot cohort. However, c
Externí odkaz:
https://doaj.org/article/86ccccce88334b4890153382c13043e0
Autor:
Joris van de Haar, Xuhui Ma, Salo N. Ooft, Pim W. van der Helm, Louisa R. Hoes, Sara Mainardi, David J. Pinato, Kristi Sun, Lisa Salvatore, Giampaolo Tortora, Ina Valeria Zurlo, Silvana Leo, Riccardo Giampieri, Rossana Berardi, Fabio Gelsomino, Valeria Merz, Federica Mazzuca, Lorenzo Antonuzzo, Gerardo Rosati, Chara Stavraka, Paul Ross, Maria Grazia Rodriquenz, Michele Pavarana, Carlo Messina, Timothy Iveson, Federica Zoratto, Anne Thomas, Elisabetta Fenocchio, Margherita Ratti, Ilaria Depetris, Massimiliano Cergnul, Cristina Morelli, Michela Libertini, Alessandro Parisi, Michele De Tursi, Nicoletta Zanaletti, Ornella Garrone, Janet Graham, Raffaella Longarini, Stefania Maria Gobba, Angelica Petrillo, Emiliano Tamburini, Nicla La Verde, Fausto Petrelli, Vincenzo Ricci, Lodewyk F. A. Wessels, Michele Ghidini, Alessio Cortellini, Emile E. Voest, Nicola Valeri
Publikováno v:
Nature Medicine
Genomics has greatly improved how patients with cancer are being treated; however, clinical-grade genomic biomarkers for chemotherapies are currently lacking. Using whole-genome analysis of 37 patients with metastatic colorectal cancer (mCRC) treated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fb49b9ab0cd07171cb1da7854395935
https://doi.org/10.1038/s41591-023-02240-8
https://doi.org/10.1038/s41591-023-02240-8
Autor:
Meghan J. Elliott, Selina Allu, Mary Beaucage, Susan McKenzie, Joanne Kappel, Rebecca Harvey, Louise Morrin, Steven Soroka, Janet Graham, Cheryl Harding, Maury Pinsk, Heather Harris, Mila Tang, Braden Manns
Publikováno v:
Canadian Journal of Kidney Health and Disease, Vol 8 (2021)
Purpose of program: Integrated knowledge translation (IKT) is a collaborative approach whereby knowledge created through health research is utilized in ways that are relevant to the needs of all stakeholders. However, research teams have limited capa
Externí odkaz:
https://doaj.org/article/826f2c3ecc4e407b9bc5b254848533b3
Autor:
Catherine R. Hanna, Kathleen A. Boyd, Joanna Wincenciak, Janet Graham, Timothy Iveson, Robert J. Jones, Richard Wilson
Publikováno v:
Cancer Treatment and Research Communications, Vol 28, Iss , Pp 100445- (2021)
Introduction: Over half of the 1.5 million individuals globally who are diagnosed with colorectal cancer (CRC) present with stage II-III disease. Understanding clinician attitudes towards treatment for this group is paramount to contextualise real-wo
Externí odkaz:
https://doaj.org/article/7ff9260634b549048e4c3cffbd686726
Autor:
Frank J. E. Vajda, Terence J. O'Brien, Janet Graham, Alison A. Hitchcock, Piero Perucca, Cecilie M. Lander, Mervyn J. Eadie
Publikováno v:
Acta Neurologica Scandinavica. 146:610-614
To investigate control of epileptic seizures during pairs of successive pregnancies in antiseizure medication (ASM)-treated women with epilepsy.Analysis of seizure freedom rates during 436 pairs of successive pregnancies in Australian women with epil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::735f77f19bb8bbe6346f54f31b1df021
https://doi.org/10.1111/ane.13688
https://doi.org/10.1111/ane.13688
Autor:
Robert Brown, Jim Paul, Nadeem Siddiqui, David W. Millan, Euan Stronach, James M. Flanagan, Jenny Hersey, Janet Graham, Constanze Zeller, Jens M. Teodoridis, Wei Dai
Supplementary Tables 1-4, Figures 1-3 from Systematic CpG Islands Methylation Profiling of Genes in the Wnt Pathway in Epithelial Ovarian Cancer Identifies Biomarkers of Progression-Free Survival
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a96e7c563192babfb8cae2ccd438c9ee
https://doi.org/10.1158/1078-0432.22441858.v1
https://doi.org/10.1158/1078-0432.22441858.v1
Autor:
Robert Brown, Jim Paul, Nadeem Siddiqui, David W. Millan, Euan Stronach, James M. Flanagan, Jenny Hersey, Janet Graham, Constanze Zeller, Jens M. Teodoridis, Wei Dai
Supplementary Methods 5 from Systematic CpG Islands Methylation Profiling of Genes in the Wnt Pathway in Epithelial Ovarian Cancer Identifies Biomarkers of Progression-Free Survival
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e6f81747efd0e03535f315a0ef3098e
https://doi.org/10.1158/1078-0432.22441864
https://doi.org/10.1158/1078-0432.22441864