Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Janene, Pierce"'
Autor:
Heather M. Wojcik, Harold N. Lovvorn, Melinda Hollingshead, Janene Pierce, Howard Stotler, Andrew J. Murphy, Suzanne Borgel, Hannah M. Phelps, Hernan Correa, Alan O. Perantoni
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionWilms Tumor (WT), or nephroblastoma, is the most common pediatric kidney cancer. Most WTs display a “favorable” triphasic histology, in which the tumor is comprised of blastemal, stromal, and epithelial cell types. Blastemal predomina
Externí odkaz:
https://doaj.org/article/ea00302988104db4a573fde3beb50e09
Autor:
Heather M. Wojcik, Harold N. Lovvorn, Melinda Hollingshead, Janene Pierce, Howard Stotler, Andrew J. Murphy, Suzanne Borgel, Hannah M. Phelps, Hernan Correa, Alan O. Perantoni
IntroductionWilms Tumor (WT), or nephroblastoma, is the most common pediatric kidney cancer. Most WTs display a “favorable” triphasic histology, in which the tumor is comprised of blastemal, stromal, and epithelial cell types. Blastemal predomina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::703c2c0336d99bed27c1f404a6b4069d
https://doi.org/10.1101/2022.11.07.515473
https://doi.org/10.1101/2022.11.07.515473
Autor:
Janene Pierce, Andrew J. Murphy, Alexis Panzer, Christian de Caestecker, Gregory D. Ayers, David Neblett, Kenyi Saito-Diaz, Mark de Caestecker, Harold N. Lovvorn, III
Publikováno v:
Translational Oncology, Vol 7, Iss 6, Pp 800-811 (2014)
Wilms tumor (WT) blastema retains gene expression profiles characteristic of the multipotent nephron progenitor pool, or cap mesenchyme (CM), in the developing kidney. As a result, WT blastema and the CM are believed to represent contextual analogues
Externí odkaz:
https://doaj.org/article/2ecb52cfd93c45468736f3c586d7f5ba
Autor:
Janene Pierce, Kelli L. Boyd, Debra L. Friedman, Ann Richmond, Jessica V. Kaczmarek, Sheau-Chiann Chen, Craig W. Lindsley, Carley M. Bogan, Jennifer B Nadelmann, Jasmine H. Francis, Terry Hsieh, Marion W. Calcutt, David H. Abramson, Albert Liao, Thomas M. Bridges, Anthony B. Daniels
Publikováno v:
The British Journal of Ophthalmology
BackgroundCurrent melphalan-based intravitreal regimens for retinoblastoma (RB) vitreous seeds cause retinal toxicity. We assessed the efficacy and toxicity of topotecan monotherapy compared with melphalan in our rabbit model and patient cohort.Metho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::962f98673a60fcbef2a73f96322f655e
https://doi.org/10.1136/bjophthalmol-2020-318529
https://doi.org/10.1136/bjophthalmol-2020-318529
Autor:
Andrew J. Murphy, Christian de Caestecker, Janene Pierce, Scott C. Boyle, Gregory D. Ayers, Zhiguo Zhao, Jaime M. Libes, Hernan Correa, Teagan Walter, Stacey S. Huppert, Alan O. Perantoni, Mark P. de Caestecker, Harold N. Lovvorn, III
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 14, Iss 12, Pp 1153-1163 (2012)
Hepatoblastoma, the most common pediatric liver cancer, consists of epithelial mixed embryonal/fetal (EMEF) and pure fetal histologic subtypes, with the latter exhibiting a more favorable prognosis. Few embryonal histology markers that yield insight
Externí odkaz:
https://doaj.org/article/0ca02d00ae4f45f28a4e012902e98800
Autor:
Xiao Liu, Carley M. Bogan, Yuankai K. Tao, Thomas M. Bridges, Craig W. Lindsley, Sheau-Chiann Chen, Ann Richmond, Debra L. Friedman, Kelli L. Boyd, Anthony B. Daniels, Jessica V. Kaczmarek, M. Wade Calcutt, Qi Liu, Janene Pierce
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose Current melphalan-based regimens for intravitreal chemotherapy for retinoblastoma vitreous seeds are effective but toxic to the retina. Thus, alternative agents are needed. Based on the known biology of histone deacetylases (HDACs) in the ret
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af2a5b20aac5b1eafe111a720c0ea845
https://doi.org/10.1167/iovs.62.14.8
https://doi.org/10.1167/iovs.62.14.8
Autor:
Pranav R. Santapuram, Jessica V. Kaczmarek, Anthony B. Daniels, Debra L. Friedman, Yuankai K. Tao, Michael T. Froehler, Ann Richmond, Sheau-Chiann Chen, Janene Pierce, Emma Schremp, Marion W. Calcutt, Tatsuki Koyama, Carley M. Bogan, Kelli L. Boyd
Publikováno v:
Translational Vision Science & Technology. 10:10
Purpose Through controlled comparative rabbit experiments and parallel patient studies, our purpose was to understand mechanisms underlying differences in efficacy and toxicity between intra-arterial chemotherapy (IAC) and intravenous chemotherapy (I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da595a22c0122602be3a000797b7557a
https://doi.org/10.1167/tvst.10.11.10
https://doi.org/10.1167/tvst.10.11.10
Autor:
Cameron A. Stone, Liping Du, Michael T. Froehler, Janene Pierce, Kelli L. Boyd, Debra L. Friedman, Anthony B. Daniels, Ivan Bozic, Sheau-Chiann Chen, Amy H. Nunnally, Pranav R. Santapuram, Yuankai K. Tao, Ann Richmond, Lauren E. Himmel
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose To use our intra-arterial chemotherapy (IAC) rabbit model to assess the impact of IAC procedure, drug, dose, and choice of technique on ocular structure and function, to study the nature and etiology of IAC toxicity, and to compare to observa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a03960d3988fbe5cf6a5b270226c53e6
https://pubmed.ncbi.nlm.nih.gov/30882851
https://pubmed.ncbi.nlm.nih.gov/30882851
Autor:
Andrew J. Murphy, Hannah M. Phelps, Hernan Correa, Jun Qian, Pierre P. Massion, Harold N. Lovvorn, Janene Pierce
Publikováno v:
J Pediatr Surg
BACKGROUND/PURPOSE: Wilms tumor (WT) is the most common childhood kidney cancer globally. Our prior unbiased proteomic screen of WT disparities revealed increased expression of Fragile X-Related 1 (FXR1) in Kenyan specimens where survival is dismal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e27cc02df01f14647db1a1d6f3a01289
https://pubmed.ncbi.nlm.nih.gov/30894247
https://pubmed.ncbi.nlm.nih.gov/30894247
Autor:
Janene Pierce, Anthony B. Daniels, Terry Hsieh, Ann Richmond, Stephanie D. Doss, Kelli L. Boyd, Yuankai K. Tao, Jasmine H. Francis, Albert Liao, David H. Abramson, Carley M. Bogan, Sheau-Chiann Chen, Debra L. Friedman
Publikováno v:
Exp Eye Res
The use of intravitreal chemotherapy has revolutionized the treatment of advanced intraocular retinoblastoma, as intravitreal melphalan has enabled difficult-to-treat vitreous tumor seeds to be controlled, leading to many more eyes being saved. Howev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7366de2c118876286c2becbfcb646a94
https://doi.org/10.1016/j.exer.2021.108439
https://doi.org/10.1016/j.exer.2021.108439