Výsledky vyhledávání - "Janendra K. Batra"

Akademický článek

ClpB is an essential stress regulator of Mycobacterium tuberculosis and endows survival advantage to dormant bacilli

Autor: Prajna Tripathi, Lalit K. Singh, Sujata Kumari, Owais R. Hakiem, Janendra K. Batra

Publikováno v: International Journal of Medical Microbiology, Vol 310, Iss 3, Pp 151402- (2020)

The ability to tolerate multiple host derived stresses, resist eradication and persist within the infected individuals is central to the pathogenicity of Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB). Mycobacterial surviv

Externí odkaz: https://doaj.org/article/d240f74531eb4d52a4336e491f847887

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Akademický článek

The amino‐terminal domain of Mycobacterium tuberculosis ClpB protein plays a crucial role in its substrate disaggregation activity

Autor: Prajna Tripathi, Priyanka Parijat, Virendra Kumar Patel, Janendra K. Batra

Publikováno v: FEBS Open Bio, Vol 8, Iss 10, Pp 1669-1690 (2018)

Mycobacterium tuberculosis (Mtb) is known to persist in extremely hostile environments within host macrophages. The ability to withstand such proteotoxic stress comes from its highly conserved molecular chaperone machinery. ClpB, a unique member of t

Externí odkaz: https://doaj.org/article/915bb9c4739a4a288ef92b69bc81e01e

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Immuno-informatic Prediction of B and T cell Epitopes of Cysteine Protease Allergen from Phaseolus vulgaris with Cross-reactive Potential and Population Coverage

Autor: Naveen Arora, Akansha Sharma, Srishti Vashisht, Shailendra Nath Gaur, Janendra K. Batra

Publikováno v: Current Protein & Peptide Science. 23:475-494

Background:In-silico mapping of epitopes by immune-informatics has simplified the efforts towards understanding antigen-antibody interactions. The knowledge of allergen epitopes may help in advancing the diagnosis and therapy of allergic diseases.Obj

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4abaed30837f28867abacb2c04ea12d3
https://doi.org/10.2174/1389203723666220804124927

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Immuno-informatic Prediction of B and T cell Epitopes of Cysteine Protease Allergen from

Autor: Akansha, Sharma, Srishti, Vashisht, Shailendra Nath, Gaur, Janendra K, Batra, Naveen, Arora

Publikováno v: Current proteinpeptide science. 23(7)

In-silico mapping of epitopes by immune-informatics has simplified the efforts towards understanding antigen-antibody interactions. The knowledge of allergen epitopes may help in advancing the diagnosis and therapy of allergic diseases.This study was

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::947628e4a0954ef1ab37e9bbfe8e700b
https://pubmed.ncbi.nlm.nih.gov/35927799

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Akademický článek

Influence of Conformation of M. tuberculosis RNase P Protein Subunit on Its Function.

Autor: Alla Singh, Shah Ubaid-ullah, Anup K Ramteke, Janendra K Batra

Publikováno v: PLoS ONE, Vol 11, Iss 4, p e0153798 (2016)

RNase P is an essential enzyme that processes 5' end leader sequence of pre-tRNA to generate mature tRNA. The bacterial RNase Ps contain a RNA subunit and one protein subunit, where the RNA subunit contains the catalytic activity. The protein subunit

Externí odkaz: https://doaj.org/article/53d20c256ecc43b0a90602228369b0e9

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Antimicrobial Activity of Human Eosinophil Granule Proteins

Autor: Anu Chopra, Janendra K. Batra

Publikováno v: Methods in Molecular Biology ISBN: 9781071610947
Methods in Molecular Biology ISBN: 9781493910151

Eosinophils secrete a number of proinflammatory mediators, like cytokines, chemokines, and granule proteins which are responsible for the initiation and sustenance of inflammatory response caused by them. The eosinophil granule proteins, ECP, EDN, MB

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f6b78b78ff68c2013e4bbbcb39035cd
https://doi.org/10.1007/978-1-0716-1095-4_20

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Akademický článek

The C-terminus of ClpC1 of Mycobacterium tuberculosis is crucial for its oligomerization and function.

Autor: Divya Bajaj, Janendra K Batra

Publikováno v: PLoS ONE, Vol 7, Iss 12, p e51261 (2012)

Mycobacterium tuberculosis ClpC1 is a member of the Hsp100/Clp AAA+ family of ATPases. The primary sequence of ClpC1 contains two N-terminal domains and two nucleotide binding domains (NBD). The second NBD has a long C-terminal sub-domain containing

Externí odkaz: https://doaj.org/article/7dcc1287a08143e08be04174340f7ca9

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Insight into the functional role of unique determinants in RNA component of RNase P of Mycobacterium tuberculosis

Autor: Janendra K. Batra, Alla Singh

Publikováno v: International Journal of Biological Macromolecules. 119:937-944

RNase P, an essential ribonucleoprotein enzyme is involved in processing 5' end of pre-tRNA molecules. All bacterial RNase P holoenzymes, including that of Mycobacterim tuberculosis, an important human pathogen contain a catalytically active RNA subu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fabf99bbc9feb9726b4fdc50c9bb6233
https://doi.org/10.1016/j.ijbiomac.2018.08.013

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