Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Janelle Sharkey"'
Autor:
Carmen S M Yong, Janelle Sharkey, Belinda Duscio, Ben Venville, Wei-Zen Wei, Richard F Jones, Clare Y Slaney, Gisela Mir Arnau, Anthony T Papenfuss, Jan Schröder, Phillip K Darcy, Michael H Kershaw
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0136817 (2015)
The development of antigen-targeted therapeutics is dependent on the preferential expression of tumor-associated antigens (TAA) at targetable levels on the tumor. Tumor-associated antigens can be generated de novo or can arise from altered expression
Externí odkaz:
https://doaj.org/article/d6252cde6bfb4c0896fffc2848d364cc
Publikováno v:
Haematologica, Vol 93, Iss 6 (2008)
Background Azacitidine is a DNA methyltransferase inhibitor and cytotoxic agent known to induce apoptosis of some cancer cells. This study evaluated the pre-clinical potential of azacitidine as a therapeutic agent for multiple myeloma.Design and Meth
Externí odkaz:
https://doaj.org/article/da689c0d10ba438f85b5ce8e4fade1eb
Autor:
Michael H. Kershaw, Phillip K. Darcy, Mark J. Smyth, Reto A. Schwendener, Hollie J. Pegram, Nicole McLaughlin, Janelle Sharkey, Nicole M. Haynes, Jennifer A. Westwood
Supplementary Data from Toll-Like Receptor Triggering and T-Cell Costimulation Induce Potent Antitumor Immunity in Mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d16a5cfff3312f9b592e04cdf0bb32c
https://doi.org/10.1158/1078-0432.22440739.v1
https://doi.org/10.1158/1078-0432.22440739.v1
Autor:
Michael H. Kershaw, Phillip K. Darcy, Mark J. Smyth, Reto A. Schwendener, Hollie J. Pegram, Nicole McLaughlin, Janelle Sharkey, Nicole M. Haynes, Jennifer A. Westwood
Purpose: To determine the antitumor activity of a novel combination of two immunomodulatory agents that simultaneously direct multiple components of immunity against cancer.Experimental Design: We combined the Toll-like receptor agonist CpG 1826 with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::288b28acca980f99cd58eff002d9482e
https://doi.org/10.1158/1078-0432.c.6518029
https://doi.org/10.1158/1078-0432.c.6518029
Autor:
Mark J. Smyth, Michael H. Kershaw, Hideo Yagita, Kazuyoshi Takeda, Gurdyal S. Besra, Steven A. Porcelli, Richard W. Franck, Moriya Tsuji, Janelle Sharkey, Phillip K. Darcy, Jennifer A. Westwood, Michele W.L. Teng
Supplementary Figure 5 from Combined Natural Killer T-Cell–Based Immunotherapy Eradicates Established Tumors in Mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a41361614f73756cf133acb451834583
https://doi.org/10.1158/0008-5472.22367721
https://doi.org/10.1158/0008-5472.22367721
Autor:
Mark J. Smyth, Michael H. Kershaw, Hideo Yagita, Kazuyoshi Takeda, Gurdyal S. Besra, Steven A. Porcelli, Richard W. Franck, Moriya Tsuji, Janelle Sharkey, Phillip K. Darcy, Jennifer A. Westwood, Michele W.L. Teng
Supplementary Legends 1-5, Table 1, Methods from Combined Natural Killer T-Cell–Based Immunotherapy Eradicates Established Tumors in Mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87acc7f8e6b5b77362da4de44fc803b5
https://doi.org/10.1158/0008-5472.22367718.v1
https://doi.org/10.1158/0008-5472.22367718.v1
Autor:
Mark J. Smyth, Michael H. Kershaw, Hideo Yagita, Kazuyoshi Takeda, Gurdyal S. Besra, Steven A. Porcelli, Richard W. Franck, Moriya Tsuji, Janelle Sharkey, Phillip K. Darcy, Jennifer A. Westwood, Michele W.L. Teng
Supplementary Figure 3 from Combined Natural Killer T-Cell–Based Immunotherapy Eradicates Established Tumors in Mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bb6ab05afb12d5198c3826a8a8c53b3
https://doi.org/10.1158/0008-5472.22367727.v1
https://doi.org/10.1158/0008-5472.22367727.v1
Autor:
Mark J. Smyth, Michael H. Kershaw, Hideo Yagita, Kazuyoshi Takeda, Gurdyal S. Besra, Steven A. Porcelli, Richard W. Franck, Moriya Tsuji, Janelle Sharkey, Phillip K. Darcy, Jennifer A. Westwood, Michele W.L. Teng
A rational monoclonal antibody (mAb)-based antitumor therapy approach has previously been shown to eradicate various established experimental and carcinogen-induced tumors in a majority of mice. This therapy comprised an agonistic mAb reactive with t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5382012d77c1e12a700a7e65a859586c
https://doi.org/10.1158/0008-5472.c.6495660
https://doi.org/10.1158/0008-5472.c.6495660
Autor:
Mark J. Smyth, Michael H. Kershaw, Hideo Yagita, Kazuyoshi Takeda, Gurdyal S. Besra, Steven A. Porcelli, Richard W. Franck, Moriya Tsuji, Janelle Sharkey, Phillip K. Darcy, Jennifer A. Westwood, Michele W.L. Teng
Supplementary Figure 1 from Combined Natural Killer T-Cell–Based Immunotherapy Eradicates Established Tumors in Mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eae3521a7b22f889e10799e080696c7
https://doi.org/10.1158/0008-5472.22367733.v1
https://doi.org/10.1158/0008-5472.22367733.v1
Autor:
Mark J. Smyth, Phillip K. Darcy, Shimon Sakaguchi, Tomoyuki Yamaguchi, Nicole McLaughlin, Nadeen Zerafa, Janelle Sharkey, Bianca von Scheidt, Jeremy B. Swann, Michele W.L. Teng
Supplementary Figures 1-10 from Multiple Antitumor Mechanisms Downstream of Prophylactic Regulatory T-Cell Depletion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94ee7d9891c285a4492f0bbe14db93cf
https://doi.org/10.1158/0008-5472.22386863
https://doi.org/10.1158/0008-5472.22386863