Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Janelle S Crossgrove"'
Publikováno v:
Experimental Biology and Medicine. 230:771-776
β-Amyloid (Aβ) concentration in the cerebrospinal fluid (CSF) of the brain may be regulated by the choroid plexus, which forms a barrier between blood and brain CSF. Aβ uptake from CSF was determined as its volume of distribution (VD) into isolate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ceac8d3ffc9b3671324f044e56173a4d
https://doi.org/10.1177/153537020523001011
https://doi.org/10.1177/153537020523001011
Autor:
Janelle S Crossgrove, Robert A. Yokel
Publikováno v:
NeuroToxicology. 26:297-307
Manganese (Mn) is a required co-factor for many ubiquitous enzymes; however, chronic Mn overexposure can cause manganism, a parkinsonian-like syndrome. Previous studies showed Mn influx into brain is carrier-mediated, though the putative carrier(s) w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b05934083728da451021e2f3a3bb6408
https://doi.org/10.1016/j.neuro.2004.09.004
https://doi.org/10.1016/j.neuro.2004.09.004
Autor:
Janelle S. Crossgrove, Wei Zheng
Publikováno v:
NMR in Biomedicine. 17:544-553
Manganese (Mn) is a required element and a metabolic byproduct of the contrast agent mangafodipir trisodium (MnDPDP). The Mn released from MnDPDP is initially sequestered by the liver for first-pass elimination, which allows an enhanced contrast for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49f21983ea78f0d5181ba1b46637cd1b
https://doi.org/10.1002/nbm.931
https://doi.org/10.1002/nbm.931
Autor:
Janelle S Crossgrove, Robert A. Yokel
Publikováno v:
NeuroToxicology. 25:451-460
Manganese (Mn) is essential for and toxic to the brain. Brain Mn uptake utilizes both diffusion and transporter-mediated pathways. The divalent metal transporter-1 (DMT-1) has been suggested to mediate brain Mn uptake. The b/b Belgrade rat does not e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f57715f90ff4009a0d6c442c8e4bc6e6
https://doi.org/10.1016/j.neuro.2003.10.005
https://doi.org/10.1016/j.neuro.2003.10.005
Publikováno v:
NeuroToxicology. 24:15-22
There is concern about manganese (Mn) neurotoxicity. Mn can enter the brain by carrier-mediated influx. There have been no previous reports of investigation of Mn efflux from the brain. We used an established method that determines the rate of efflux
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58ac6cdfed15f23d98416976c91622c6
https://doi.org/10.1016/s0161-813x(02)00090-6
https://doi.org/10.1016/s0161-813x(02)00090-6
Autor:
Bonny L. Bukaveckas, David D. Allen, Janelle S Crossgrove, Susan S. Rhineheimer, Robert A. Yokel
Publikováno v:
NeuroToxicology. 24:3-13
Manganese (Mn) is an essential element and a neurotoxicant. Regulation of Mn movement across the blood-brain barrier (BBB) contributes to whether the brain Mn concentration is functional or toxic. In plasma, Mn associates with water, small molecular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2615633bd81bb9486fad808b25d0775
https://doi.org/10.1016/s0161-813x(02)00089-x
https://doi.org/10.1016/s0161-813x(02)00089-x
Publikováno v:
The FASEB Journal. 24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::556cb65220064b1dec649d68b618b46b
https://doi.org/10.1096/fasebj.24.1_supplement.604.8
https://doi.org/10.1096/fasebj.24.1_supplement.604.8
Publikováno v:
Pharmaceutical Sciences Encyclopedia
The Food and Drug Administration (FDA) protects the health of Americans by enforcing the Federal Food, Drug, and Cosmetic Act and other related public health laws. The role of the FDA in clinical trials is to help protect the rights and welfare of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c2ebd97497f6fc002d9330648cdc599
https://doi.org/10.1002/9780470571224.pse209
https://doi.org/10.1002/9780470571224.pse209
One of the notable features of Alzheimer's disease (AD) is the overabundance of beta-amyloid peptides in brain fluids, leading to the formation and deposition of insoluble amyloid plaques. Previous work in this lab demonstrates that the normal choroi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8bb150a3e12155ca0d10d71c9473ef7
https://europepmc.org/articles/PMC1950938/
https://europepmc.org/articles/PMC1950938/
Publikováno v:
Neurotoxicology. 24(1)
There is concern about manganese (Mn) neurotoxicity. Mn can enter the brain by carrier-mediated influx. There have been no previous reports of investigation of Mn efflux from the brain. We used an established method that determines the rate of efflux
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f4a1985d2bc3cd2f0d5f5297725d53fc
https://pubmed.ncbi.nlm.nih.gov/12564378
https://pubmed.ncbi.nlm.nih.gov/12564378