Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Janelle B, Leuthaeuser"'
1
Akademický článek
An Atlas of Peroxiredoxins Created Using an Active Site Profile-Based Approach to Functionally Relevant Clustering of Proteins.
Autor: Angela F Harper, Janelle B Leuthaeuser, Patricia C Babbitt, John H Morris, Thomas E Ferrin, Leslie B Poole, Jacquelyn S Fetrow
Publikováno v: PLoS Computational Biology, Vol 13, Iss 2, p e1005284 (2017)
Peroxiredoxins (Prxs or Prdxs) are a large protein superfamily of antioxidant enzymes that rapidly detoxify damaging peroxides and/or affect signal transduction and, thus, have roles in proliferation, differentiation, and apoptosis. Prx superfamily m
Externí odkaz: https://doaj.org/article/8cb546cdaeb6472caa931f2f963e252a
Zobrazit plný text záznamu
2
Isofunctional Clustering and Conformational Analysis of the Arsenate Reductase Superfamily Reveals Nine Distinct Clusters
Autor: Jacquelyn S. Fetrow, Carol A. Parish, Mikaela R Rosen, Janelle B Leuthaeuser
Publikováno v: Biochemistry. 59(44)
Arsenate reductase (ArsC) is a superfamily of enzymes that reduce arsenate. Due to active site similarities, some ArsC can function as low-molecular weight protein tyrosine phosphatases (LMW-PTPs). Broad superfamily classifications align with redox p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::355dd9089806b0cd0a311d70d164e9ed
https://pubmed.ncbi.nlm.nih.gov/33135415
Zobrazit plný text záznamu
3
An approach to functionally relevant clustering of the protein universe: Active site profile-based clustering of protein structures and sequences
Autor: Patricia C. Babbitt, Brian M. Westwood, Jacquelyn S. Fetrow, Julia D. Hayden, Thomas E. Ferrin, Kiran Kumar, Don Nguyendac, Shoshana D. Brown, Janelle B. Leuthaeuser, Brandon E. Turner, Stacy T. Knutson, John H. Morris, Gabrielle Shea, Angela F. Harper
Publikováno v: Protein Science. 26:677-699
Protein function identification remains a significant problem. Solving this problem at the molecular functional level would allow mechanistic determinant identification-amino acids that distinguish details between functional families within a superfa
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d23de9fb2e1b55656f598f9fe1240233
https://doi.org/10.1002/pro.3112
Zobrazit plný text záznamu
4
Comparison of topological clustering within protein networks using edge metrics that evaluate full sequence, full structure, and active site microenvironment similarity
Autor: Janelle B. Leuthaeuser, Stacy T. Knutson, Patricia C. Babbitt, Kiran Kumar, Jacquelyn S. Fetrow
Publikováno v: Protein Science : A Publication of the Protein Society
The development of accurate protein function annotation methods has emerged as a major unsolved biological problem. Protein similarity networks, one approach to function annotation via annotation transfer, group proteins into similarity-based cluster
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83750f0ba60997c1277ec2d0e8fe995d
http://europepmc.org/articles/PMC4570537
Zobrazit plný text záznamu
5
An Atlas of Peroxiredoxins Created Using an Active Site Profile-Based Approach to Functionally Relevant Clustering of Proteins
Autor: Jacquelyn S. Fetrow, Patricia C. Babbitt, Angela F. Harper, Leslie B. Poole, Thomas E. Ferrin, John H. Morris, Janelle B. Leuthaeuser
Publikováno v: Harper, AF; Leuthaeuser, JB; Babbitt, PC; Morris, JH; Ferrin, TE; Poole, LB; et al.(2017). An Atlas of Peroxiredoxins Created Using an Active Site Profile-Based Approach to Functionally Relevant Clustering of Proteins. PLOS COMPUTATIONAL BIOLOGY, 13(2). doi: 10.1371/journal.pcbi.1005284. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/0gz4f8dp
PLoS computational biology, vol 13, iss 2
PLoS Computational Biology
PLoS Computational Biology, Vol 13, Iss 2, p e1005284 (2017)
Peroxiredoxins (Prxs or Prdxs) are a large protein superfamily of antioxidant enzymes that rapidly detoxify damaging peroxides and/or affect signal transduction and, thus, have roles in proliferation, differentiation, and apoptosis. Prx superfamily m
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da8ff519db53edbea2d16b20bf3ce90b
http://www.escholarship.org/uc/item/0gz4f8dp
Zobrazit plný text záznamu
6
An approach to functionally relevant clustering of the protein universe: Active site profile-based clustering of protein structures and sequences
Autor: Stacy T, Knutson, Brian M, Westwood, Janelle B, Leuthaeuser, Brandon E, Turner, Don, Nguyendac, Gabrielle, Shea, Kiran, Kumar, Julia D, Hayden, Angela F, Harper, Shoshana D, Brown, John H, Morris, Thomas E, Ferrin, Patricia C, Babbitt, Jacquelyn S, Fetrow
Publikováno v: Protein Science : A Publication of the Protein Society
Protein function identification remains a significant problem. Solving this problem at the molecular functional level would allow mechanistic determinant identification—amino acids that distinguish details between functional families within a super
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::16dd10bec984a839ffd3961994756fc0
https://pubmed.ncbi.nlm.nih.gov/28054422
Zobrazit plný text záznamu
7
DASP3: identification of protein sequences belonging to functionally relevant groups
Autor: Patricia C. Babbitt, Angela F. Harper, Thomas E. Ferrin, Janelle B. Leuthaeuser, Jacquelyn S. Fetrow, John H. Morris
Publikováno v: Leuthaeuser, JB; Morris, JH; Harper, AF; Ferrin, TE; Babbitt, PC; & Fetrow, JS. (2016). DASP3: identification of protein sequences belonging to functionally relevant groups. BMC BIOINFORMATICS, 17. doi: 10.1186/s12859-016-1295-z. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/60r7f4qk
BMC bioinformatics, vol 17, iss 1
BMC Bioinformatics
Background Development of automatable processes for clustering proteins into functionally relevant groups is a critical hurdle as an increasing number of sequences are deposited into databases. Experimental function determination is exceptionally tim
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0decc5b785a4a1bb1ac1d899f2dc2696
http://www.escholarship.org/uc/item/60r7f4qk
Zobrazit plný text záznamu
8
Mutating a Highly Conserved Residue in Diverse Cytochrome P450s Facilitates Diastereoselective Olefin Cyclopropanation
Autor: Eric M. Brustad, Joshua G. Gober, Janelle B. Leuthaeuser, Amy E. Rydeen, Jacquelyn S. Fetrow, Evan J. Gibson-O'Grady
Publikováno v: Chembiochem : a European journal of chemical biology. 17(5)
Cytochrome P450s and other heme-containing proteins have recently been shown to have promiscuous activity for the cyclopropanation of olefins using diazoacetate reagents. Despite the progress made thus far, engineering selective catalysts for all pos
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ccab47139e0e71c20e461b4abc9df6d
https://pubmed.ncbi.nlm.nih.gov/27805325
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje