Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Janelle A Noble"'
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0192696 (2018)
There is a growing body of evidence suggesting that type 1 diabetes (T1D) is a genetically heterogeneous disease. However, the extent of this heterogeneity, and what observations may distinguish different forms, is unclear. One indicator may be T1D-r
Externí odkaz:
https://doaj.org/article/7cce32267b2d47239ef8c1edfce7d3ad
Autor:
Janelle A. Noble
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
More than 50 years have elapsed since the association of human leukocyte antigens (HLA) with type 1 diabetes (T1D) was first reported. Since then, methods for identification of HLA have progressed from cell based to DNA based, and the number of recog
Externí odkaz:
https://doaj.org/article/e0a65ecdbcfd4d83b5b3b3ed7f8348dd
Autor:
Nikolaos A Patsopoulos, Lisa F Barcellos, Rogier Q Hintzen, Catherine Schaefer, Cornelia M van Duijn, Janelle A Noble, Towfique Raj, IMSGC, ANZgene, Pierre-Antoine Gourraud, Barbara E Stranger, Jorge Oksenberg, Tomas Olsson, Bruce V Taylor, Stephen Sawcer, David A Hafler, Mary Carrington, Philip L De Jager, Paul I W de Bakker
Publikováno v:
PLoS Genetics, Vol 9, Iss 11, p e1003926 (2013)
The major histocompatibility complex (MHC) region is strongly associated with multiple sclerosis (MS) susceptibility. HLA-DRB1*15:01 has the strongest effect, and several other alleles have been reported at different levels of validation. Using SNP d
Externí odkaz:
https://doaj.org/article/6e4e6d6e785f43918ef55c820b6ebf1f
Autor:
Nancy Keller, Suruchi Bhatia, Jeanah N Braden, Ginny Gildengorin, Jameel Johnson, Rachel Yedlin, Teresa Tseng, Jacquelyn Knapp, Nicole Glaser, Paula Jossan, Shawn Teran, Erinn T Rhodes, Janelle A Noble
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e32773 (2012)
To test the hypothesis that clinical observations made at patient presentation can distinguish type 2 diabetes (T2D) from type 1 diabetes (T1D) in pediatric patients aged 2 to 18.Medical records of 227 African American and 112 Hispanic American pedia
Externí odkaz:
https://doaj.org/article/3a87f9911b5c4172b6ea71452f7b6d11
Autor:
Lisa F Barcellos, Suzanne L May, Patricia P Ramsay, Hong L Quach, Julie A Lane, Joanne Nititham, Janelle A Noble, Kimberly E Taylor, Diana L Quach, Sharon A Chung, Jennifer A Kelly, Kathy L Moser, Timothy W Behrens, Michael F Seldin, Glenys Thomson, John B Harley, Patrick M Gaffney, Lindsey A Criswell
Publikováno v:
PLoS Genetics, Vol 5, Iss 10, p e1000696 (2009)
A substantial genetic contribution to systemic lupus erythematosus (SLE) risk is conferred by major histocompatibility complex (MHC) gene(s) on chromosome 6p21. Previous studies in SLE have lacked statistical power and genetic resolution to fully def
Externí odkaz:
https://doaj.org/article/acdf052b8c0640a681508f2500c87305
Autor:
Stéphane Besançon, Denira Govender, Assa Traore Sidibé, Janelle Annette Noble, Amagara Togo, Julie Ann Lane, Steven John Mack, Mark A. Atkinson, Clive Henry Wasserfall, Faizy Kakkat, Gregory G. N. Martin, Graham David Ogle
Publikováno v:
Pediatric diabetes. 23(8)
Limited information is available regarding youth-onset diabetes in Mali. We investigated demographic, clinical, biochemical, and genetic features in new diabetes cases in children and adolescents.The study was conducted at Hôpital du Mali in Bamako.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10237b93359b682f11365bc84b1d9b56
https://pubmed.ncbi.nlm.nih.gov/36062396
https://pubmed.ncbi.nlm.nih.gov/36062396
Autor:
Leif Groop, Xueying Zheng, Jinhua Yan, Guo Wang Lin, Wenqian Ren, Bin Yao, Daizhi Yang, Sihui Luo, Hua Liang, Yingxin Xian, Janelle A. Noble, Jianping Weng, Ziyu Jiang, Jin Xin Bei, Wen Xu
Publikováno v:
Diabetologia
Aims/hypothesis The study aimed to investigate the effects of HLA class I genes on susceptibility to type 1 diabetes with different onset ages, in addition to the well-established effects of HLA class II genes. Methods A total of 361 patients with ty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6c0d9e6c3722e787188a80b64172d4a
http://europepmc.org/articles/PMC8382651
http://europepmc.org/articles/PMC8382651
Autor:
Clive Wasserfall, Graham D. Ogle, Tomader Ali Mohammed Ibrahim, Julie A. Lane, Steven J. Mack, Janelle A. Noble, Mark A. Atkinson, Mohammed O. Hussien, Mohamed A. Abdullah, Gregory George Noble Martin, Denira Govender
Publikováno v:
Pediatric diabetes, vol 22, iss 5
Pediatr Diabetes
Pediatr Diabetes
ObjectiveTo further understand clinical and biochemical features, and HLA-DRB1 genotypes, in new cases of diabetes in Sudanese children and adolescents.Research design and methodsDemographic characteristics, clinical information, and biochemical para
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c761ff115b149c1ef4e527380cb43d32
https://escholarship.org/uc/item/4471q3qm
https://escholarship.org/uc/item/4471q3qm
Autor:
Asher Fawwad, Abdul Basit, Janelle A. Noble, Clive Wasserfall, Mohammad Yakoob Ahmedani, Graham D. Ogle, Denira Govender, Steven J. Mack, Mark A. Atkinson, Julie A. Lane
Publikováno v:
Diabetes Research and Clinical Practice. 149:9-17
Published information on diabetes in Pakistani youth is limited. We aimed to investigate the demographic, clinical, and biochemical features, and HLA-DRB1 alleles in new cases of diabetes affecting children and adolescents
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd3f86152377b9bc683303fe91b770a9
https://doi.org/10.1016/j.diabres.2019.01.023
https://doi.org/10.1016/j.diabres.2019.01.023
Autor:
Shana L. McDevitt, Chelsea Marie, G. Brett Moreau, Masud Alam, Jeffrey R. Donowitz, Janelle A. Noble, Rashidul Haque, William A. Petri, Beth D. Kirkpatrick, Sayo McCowin
Publikováno v:
EBioMedicine, Vol 67, Iss, Pp 103346-(2021)
EBioMedicine
EBioMedicine
Background genetic susceptibility to infection is mediated by numerous host factors, including the highly diverse, classical human leukocyte antigen (HLA) genes, which are critical genetic determinants of immunity. We systematically evaluated the eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce4f961b7c0a51da7a8933044777b87d
http://www.sciencedirect.com/science/article/pii/S2352396421001390
http://www.sciencedirect.com/science/article/pii/S2352396421001390