Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Janelle, Sauvageau"'
Autor:
Janelle Sauvageau, Izel Koyuturk, Frank St. Michael, Denis Brochu, Marie-France Goneau, Ian Schoenhofen, Sylvie Perret, Alexandra Star, Anna Robotham, Arsalan Haqqani, John Kelly, Michel Gilbert, Yves Durocher
Publikováno v:
Communications Chemistry, Vol 6, Iss 1, Pp 1-13 (2023)
Abstract Glycosylation is a key quality attribute that must be closely monitored for protein therapeutics. Established assays such as HILIC-Fld of released glycans and LC-MS of glycopeptides work well for glycoproteins with a few glycosylation sites
Externí odkaz:
https://doaj.org/article/b6b1904909a242f99f4b91f266f9ce1c
Autor:
Simon Joubert, Matthew Stuible, Simon Lord‐Dufour, Linda Lamoureux, François Vaillancourt, Sylvie Perret, Manon Ouimet, Alex Pelletier, Louis Bisson, Rohan Mahimkar, Phuong Lan Pham, Helene L′Ecuyer‐Coelho, Marjolaine Roy, Robert Voyer, Jason Baardsnes, Janelle Sauvageau, Frank St‐Michael, Anna Robotham, John Kelly, Andrea Acel, Joseph D. Schrag, Majida El Bakkouri, Yves Durocher
Protein expression from stably transfected Chinese hamster ovary (CHO) clones is an established but time-consuming method for manufacturing therapeutic recombinant proteins. The use of faster, alternative approaches, such as non-clonal stable pools,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9da55dfe24cf776fdd3615002431c3ff
https://doi.org/10.1002/bit.28387
https://doi.org/10.1002/bit.28387
Autor:
Mohammad P. Jamshidi, Chantelle Cairns, Simon Chong, Frank St. Michael, Evgeny V. Vinogradov, Andrew D. Cox, Janelle Sauvageau
Publikováno v:
ACS Infectious Diseases. 8:1347-1355
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1cccba10277bb61bec3faf632a12da11
https://doi.org/10.1021/acsinfecdis.2c00184
https://doi.org/10.1021/acsinfecdis.2c00184
Autor:
Chantelle M. Cairns, Frank St. Michael, Mohammad Jamshidi, Henk van Faassen, Qingling Yang, Kevin A. Henry, Greg Hussack, Janelle Sauvageau, Evgeny V. Vinogradov, Andrew D. Cox
Publikováno v:
ACS Infectious Diseases. 8:1336-1346
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2c8241b610620740373f6dc8f8c81f7
https://doi.org/10.1021/acsinfecdis.2c00183
https://doi.org/10.1021/acsinfecdis.2c00183
Autor:
Omar Farnós, Alina Venereo-Sánchez, Xingge Xu, Cindy Chan, Shantoshini Dash, Hanan Chaabane, Janelle Sauvageau, Fouad Brahimi, Uri Saragovi, Denis Leclerc, Amine A. Kamen
Publikováno v:
Vaccines, Vol 8, Iss 4, p 654 (2020)
Vaccine design strategies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are focused on the Spike protein or its subunits as the main antigen target of neutralizing antibodies. In this work, we propose rapid production methods o
Externí odkaz:
https://doaj.org/article/aec5cc940b18476b86bcaaac7e93cb02
Publikováno v:
Synthesis. 54:79-91
Lipopolysaccharide biosynthesis metabolites, such as d-glycero-β-d-manno-heptopyranosyl 1,7-diphosphate, d-glycero-β-d-manno-heptopyranosyl phosphate, and adenosine 5′-(l-glycero-β-d-manno-heptopyranosyl)diphosphate, have been found to activate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27c9805ec0aad2b32ca289f826b2c677
https://doi.org/10.1055/s-0040-1720179
https://doi.org/10.1055/s-0040-1720179
Autor:
Izel Koyuturk, Surbhi Kedia, Anna Robotham, Alexandra Star, Denis Brochu, Janelle Sauvageau, John Kelly, Michel Gilbert, Yves Durocher
Publikováno v:
Biotechnology and Bioengineering. 119
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5acf44b3553b84e1e7fea509da157996
https://doi.org/10.1002/bit.28204
https://doi.org/10.1002/bit.28204
Autor:
Frank St. Michael, Kenneth Chisholm, Janelle Sauvageau, Mohammad P. Jamshidi, Dean Williams, Andrew D. Cox
Publikováno v:
The Journal of Organic Chemistry. 86:2184-2199
Pathogen-associated molecular patterns activate the immune system via pattern recognition receptors. Recently, newly discovered pathogen-associated molecular patterns, d-glycero-β-d-mannoheptose phosphate and d-glycero-β-d-mannoheptose 1,7-biphosph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10eac2994a98b2af537b1f78d24403d7
https://doi.org/10.1021/acs.joc.0c02333
https://doi.org/10.1021/acs.joc.0c02333
Autor:
Izel Koyuturk, Surbhi Kedia, Anna Robotham, Alexandra Star, Denis Brochu, Janelle Sauvageau, John Kelly, Michel Gilbert, Yves Durocher
Publikováno v:
Biotechnology and bioengineeringREFERENCES. 119(9)
Alpha-1-antitrypsin (A1AT) is a serine protease inhibitor which blocks the activity of serum proteases including neutrophil elastase to protect the lungs. Its deficiency is known to increase the risk of pulmonary emphysema as well as chronic obstruct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af05b8969636b0bbb1e9fdd4a8622e07
https://pubmed.ncbi.nlm.nih.gov/35508753
https://pubmed.ncbi.nlm.nih.gov/35508753
Autor:
Hui Qian, Zygmunt J. Jakubek, Renu Dudani, Lise Deschatelets, Michael J McCluskie, Evguenii Vinogradov, Janelle Sauvageau, Bassel Akache, Blair A. Harrison, Felicity C. Stark, Mohammad P. Jamshidi, Lakshmi Krishnan, Vandana Chandan, Yimei Jia, Dean Williams
Publikováno v:
Journal of Liposome Research. 31:237-245
Archaeosomes, composed of sulphated lactosyl archaeol (SLA) glycolipids, have been proven to be an effective vaccine adjuvant in multiple preclinical models of infectious disease or cancer. In addition to efficacy, the stability of vaccine components
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9b16c719f117391de57fca93c4f5abf
https://doi.org/10.1080/08982104.2020.1786115
https://doi.org/10.1080/08982104.2020.1786115