Výsledky vyhledávání - "Janell Seeger"

Directional Coronary Atherectomy for the Diagnosis and Treatment of Radiation-Induced Coronary Artery Stenosis

Autor: Daniel Bunker, Douglas Ackerman, Abraham Joseph, Janell Seeger, J. David Talley

Publikováno v: Journal of Interventional Cardiology. 8:355-358

While radiation therapy has been known to cause myocardial and pericardial damage, its role in accentuating coronary artery disease in the absence of traditional cardiovascular risk factors has been controversial. As younger patients with treatable c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e6008e1feae4a784b56dd78d9445399
https://doi.org/10.1111/j.1540-8183.1995.tb00557.x

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Long-term intravenous hydroxyurea infusions in patients with advanced cancer. A phase I trial

Autor: Thomas M. Woodcock, Subash P. Sheth, Daniel M. Sullivan, Martin S. Blumenreich, Eliza J. Sherrill, Kim A. Lalley, Michael J. Kellihan, John T. Hamm, U. Geetha Joseph, Patrick S. Gentile, Janell Seeger

Publikováno v: Cancer. 71:2828-2832

Background. Hydroxyurea is an S-phase specific drug. Constant exposure of tumor cells with a low S-phase fraction to the agent may result in improved cell kill. Because of its short half-life, a continuous intravenous infusion may result in better tu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::60d78ea911295c0a58deeef1eb0b9567
https://doi.org/10.1002/1097-0142(19930501)71:9<2828::aid-cncr2820710924>3.0.co

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A phase II clinical trial of ZD1839 (Iressa) in combination with docetaxel as first-line treatment in patients with advanced breast cancer

Autor: Jane M. Raymond, Samuel A. Jacobs, Sheri K. Dennison, Janell Seeger, Terrence P. Cescon, John W Wilson, Norman Wolmark, Charles E. Geyer, Sandra M. Swain

Publikováno v: Investigational new drugs. 25(6)

This was a phase II multi-institutional trial to determine the efficacy and tolerability of gefitinib (Iressatrade) and docetaxel as first-line treatment in patients with metastatic breast cancer. All patients had histologically confirmed breast canc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23f0370176be955ed9605329b2a84b2d
https://pubmed.ncbi.nlm.nih.gov/17563856

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Inefficacy of Low-Dose Continuous Oral Etoposide in Non-Small Cell Lung Cancer

Autor: Martin S. Blumenreich, Subash P. Sheth, Carole L. Miller, Elisa S. Farnsley, Michael J. Kellihan, U. Geetha Joseph, John T. Hamm, Janell Seeger, Linda H. Robinson, Pamela C. Hagan, Daniel M. Sullivan, Thomas M. Woodcock

Publikováno v: American Journal of Clinical Oncology. 17:163-165

Etoposide is more active in small cell lung cancer when given over 5 days than as a single injection. To examine this concept further, we designed this Phase II study in NSCLC using continuous low-dose oral etoposide. We enrolled 19 patients with mea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47955516816770947c3380581c008345
https://doi.org/10.1097/00000421-199404000-00015

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High-dose chlorambucil and dexamethasone for relapsed non-Hodgkin's lymphomas

Autor: Martin S. Blumenreich, Janell Seeger, Thomas M. Woodcock, Terence J. Hadley, Benjamin Djulbegovic, John T. Hamm, Geetha Joseph

Publikováno v: American journal of clinical oncology. 16(4)

Twenty patients with relapsed or refractory non-Hodgkin's lymphoma were treated with high-dose chlorambucil (14 mg/m2 every 6 hours for 6 doses) and dexamethasone (40 mg/day for 5 days). There was a 45% response rate with 17% complete responses. The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92f03876c74bdde99a6b277f294fd7dd
https://pubmed.ncbi.nlm.nih.gov/8328409

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Hepatic Perfusion with FUdR Utilizing an Implantable System in Patients with Liver Primary Cancer or Metastatic Cancer Confined to the Liver

Autor: Martin S. Blumenreich, Thomas M. Woodcock, J. David Richardson, Janell Seeger

Publikováno v: Cancer Investigation. 7:1-6

Nineteen patients with colorectal adencarcinoma, three with cholangiocarcinoma, two with hepatocellular carcinoma, and one with carcinoid were treated with hepatic artery infusion chemotherapy. An implantable pump system was used to deliver floxuridi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45a8019466f753fbb8441c7a8f75571e
https://doi.org/10.3109/07357908909038262

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Systemic Therapy of Malignant Melanoma

Autor: Stephen P. Richman, Janell Seeger, Joseph C. Allegra

Publikováno v: Medical Clinics of North America. 70:89-94

To date, the therapeutic challenge of improving the poor prognosis of malignant melanoma has not been met by adjuvant therapy for disseminated disease. But the tedious determination of ineffective therapy has closed some lines of research and opened

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4bea34eac2072367e7445e524adc727
https://doi.org/10.1016/s0025-7125(16)30970-1

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Prolongation of isovolumetric relaxation time as assessed by Doppler echocardiography predicts doxorubicin-induced systolic dysfunction in humans

Autor: Janell Seeger, Norman E. Liddell, Terence J. Hadley, Marcus F. Stoddard, Daniel M. Sullivan, Joel Kupersmith

Publikováno v: Journal of the American College of Cardiology. (1):62-69

A reasonably sensitive and specific noninvasive test for doxorubicin cardiotoxicity is needed. In addition, few data exist on the short- and long-term effects of doxorubicin on diastolic filling. To determine if pulsed Doppler indexes of diastolic fi

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