Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Janell L.M. Smith"'
Autor:
Evgeny Shlevkov, Himanish Basu, Mark-Anthony Bray, Zheng Sun, Wei Wei, Kaan Apaydin, Kyle Karhohs, Pin-Fang Chen, Janell L.M. Smith, Ole Wiskow, Kasper Roet, Xuan Huang, Kevin Eggan, Anne E. Carpenter, Robin J. Kleiman, Thomas L. Schwarz
Publikováno v:
Cell Reports, Vol 28, Iss 12, Pp 3224-3237.e5 (2019)
Summary: Dysregulated axonal trafficking of mitochondria is linked to neurodegenerative disorders. We report a high-content screen for small-molecule regulators of the axonal transport of mitochondria. Six compounds enhanced mitochondrial transport i
Externí odkaz:
https://doaj.org/article/914ac8b6b6974b42ac32cfd413e51640
Autor:
Francesco Limone, Irune Guerra San Juan, Jana M. Mitchell, Janell L.M. Smith, Kavya Raghunathan, Daniel Meyer, Sulagna Dia Ghosh, Alexander Couto, Joseph R. Klim, Brian J. Joseph, John Gold, Curtis J. Mello, James Nemesh, Brittany M. Smith, Matthijs Verhage, Steven A. McCarroll, Olli Pietiläinen, Ralda Nehme, Kevin Eggan
Publikováno v:
Cell Reports, 42(1):111896, 1-21. Cell Press
Cell Reports, 42(1):111896. Cell Press
Limone, F, Guerra San Juan, I, Mitchell, J M, Smith, J L M, Raghunathan, K, Meyer, D, Ghosh, S D, Couto, A, Klim, J R, Joseph, B J, Gold, J, Mello, C J, Nemesh, J, Smith, B M, Verhage, M, McCarroll, S A, Pietiläinen, O, Nehme, R & Eggan, K 2023, ' Efficient generation of lower induced motor neurons by coupling Ngn2 expression with developmental cues ', Cell Reports, vol. 42, no. 1, 111896, pp. 1-21 . https://doi.org/10.1016/j.celrep.2022.111896
Limone, F, Guerra San Juan, I, Mitchell, J M, Smith, J L M, Raghunathan, K, Meyer, D, Ghosh, S D, Couto, A, Klim, J R, Joseph, B J, Gold, J, Mello, C J, Nemesh, J, Smith, B M, Verhage, M, McCarroll, S A, Pietiläinen, O, Nehme, R & Eggan, K 2023, ' Efficient generation of lower induced motor neurons by coupling Ngn2 expression with developmental cues ', Cell Reports, vol. 42, no. 1, 111896 . https://doi.org/10.1016/j.celrep.2022.111896
Cell Reports, 42(1):111896. Cell Press
Limone, F, Guerra San Juan, I, Mitchell, J M, Smith, J L M, Raghunathan, K, Meyer, D, Ghosh, S D, Couto, A, Klim, J R, Joseph, B J, Gold, J, Mello, C J, Nemesh, J, Smith, B M, Verhage, M, McCarroll, S A, Pietiläinen, O, Nehme, R & Eggan, K 2023, ' Efficient generation of lower induced motor neurons by coupling Ngn2 expression with developmental cues ', Cell Reports, vol. 42, no. 1, 111896, pp. 1-21 . https://doi.org/10.1016/j.celrep.2022.111896
Limone, F, Guerra San Juan, I, Mitchell, J M, Smith, J L M, Raghunathan, K, Meyer, D, Ghosh, S D, Couto, A, Klim, J R, Joseph, B J, Gold, J, Mello, C J, Nemesh, J, Smith, B M, Verhage, M, McCarroll, S A, Pietiläinen, O, Nehme, R & Eggan, K 2023, ' Efficient generation of lower induced motor neurons by coupling Ngn2 expression with developmental cues ', Cell Reports, vol. 42, no. 1, 111896 . https://doi.org/10.1016/j.celrep.2022.111896
Human pluripotent stem cells (hPSCs) are a powerful tool for disease modeling of hard-to-access tissues (such as the brain). Current protocols either direct neuronal differentiation with small molecules or use transcription-factor-mediated programmin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20846473ea56d08b4a5ee688ff900315
http://hdl.handle.net/10138/357693
http://hdl.handle.net/10138/357693
Autor:
Janell L.M. Smith, Mark-Anthony Bray, Thomas Schwarz, Robin J. Kleiman, Ole Wiskow, Kasper C. D. Roet, Kyle W. Karhohs, Wei Wei, Anne E. Carpenter, Kaan Apaydin, Evgeny Shlevkov, Pin-Fang Chen, Himanish Basu, Xuan Huang, Kevin Eggan, Zheng Sun
Publikováno v:
Cell Reports, Vol 28, Iss 12, Pp 3224-3237.e5 (2019)
Cell reports
Cell reports
SUMMARY Dysregulated axonal trafficking of mitochondria is linked to neurodegenerative disorders. We report a high-content screen for small-molecule regulators of the axonal transport of mitochondria. Six compounds enhanced mitochondrial transport in