Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Janel M. Dempsey"'
Autor:
Kirk M. Atkinson, Sasha Padilla-Coley, Tia S. Jarvis, Kejia Shi, Janel M. Dempsey, Madushani Dharmarwardana, Bradley D. Smith
Publikováno v:
Chem Commun (Camb)
A supramolecular dye-capture system comprising anionic amidosquaraine guest and macrocyclic tetralactam host exhibits nanomolar affinity and “turn on” visible fluorescence. Utility is demonstrated with a new fluorescent assay for liposome leakage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22957e9cc7120ff0dc4fbcebeed7d3ab
https://doi.org/10.1039/d1cc05039g
https://doi.org/10.1039/d1cc05039g
Autor:
Janel M. Dempsey, Braden P. Matthews, Hannah H. McGarraugh, Caroline R Christmann, Canjia Zhai, Bradley D. Smith, Cynthia L. Schreiber
Publikováno v:
Bioconjug Chem
New methods are described for the construction of targeted fluorescence probes for imaging cancer and the assessment of tumor targeting performance in a living mouse model. A novel noncovalent assembly process was used to fabricate a set of structura
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11fec4efdf821df5ab62ccb027a2fcc2
https://doi.org/10.1021/acs.bioconjchem.9b00750
https://doi.org/10.1021/acs.bioconjchem.9b00750
Autor:
Paul Helquist, Michael Grigalunas, Olaf Wiest, Gang Liu, Atul Bhardwaj, Luke Kiefer, Daniel Wüstner, Emily M. Work, Janel M. Dempsey, Rasmin Kaur, Guillermo Ferraudi
Publikováno v:
J Org Chem
Work, E M, Ferraudi, G, Kiefer, L, Liu, G, Grigalunas, M, Bhardwaj, A, Kaur, R, Dempsey, J M, Wüstner, D, Helquist, P & Wiest, O 2021, ' Design, Synthesis, and Evaluation of a Luminescent Cholesterol Mimic ', Journal of Organic Chemistry, vol. 86, no. 2, pp. 1612–1621 . https://doi.org/10.1021/acs.joc.0c02460
Work, E M, Ferraudi, G, Kiefer, L, Liu, G, Grigalunas, M, Bhardwaj, A, Kaur, R, Dempsey, J M, Wüstner, D, Helquist, P & Wiest, O 2021, ' Design, Synthesis, and Evaluation of a Luminescent Cholesterol Mimic ', Journal of Organic Chemistry, vol. 86, no. 2, pp. 1612–1621 . https://doi.org/10.1021/acs.joc.0c02460
The development of new chemical tools with improved properties is essential to chemical and cell biology. Of particular interest is the development of mimics of small molecules with important cellular function that allow the direct observation of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13b50b1a85fe4cccb8ae56c4577940c4
https://pubmed.ncbi.nlm.nih.gov/33369429
https://pubmed.ncbi.nlm.nih.gov/33369429
Publikováno v:
The Journal of Organic Chemistry. 82:5819-5825
Squaraine rotaxanes are mechanically interlocked molecules comprised of a dumbbell shaped squaraine dye inside a tetralactam macrocycle. Previous squaraine rotaxanes have employed planar squaraine dyes with 4-aminophenyl, 2-aminothiophene, or N-amino
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbe1b6a556d0114f4907099425054f79
https://doi.org/10.1021/acs.joc.7b00655
https://doi.org/10.1021/acs.joc.7b00655
Autor:
Bradley D. Smith, Janel M. Dempsey, Hannah H. McGarraugh, A. Johnson, Cynthia L. Schreiber, Canjia Zhai, Shannon Stoffel
Publikováno v:
Chem Commun (Camb)
A new tetralactam macrocycle was prepared and found to encapsulate deep-red and near-infrared squaraine and croconaine dyes in water with tunable threading kinetics. The new supramolecular paradigm of guest back-folding was used to increase macrocycl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8d7234e6eb3029049c7618055685e8a
https://europepmc.org/articles/PMC6827183/
https://europepmc.org/articles/PMC6827183/
Autor:
Caroline R Christmann, Braden P. Matthews, Janel M. Dempsey, Hannah H. McGarraugh, Canjia Zhai, Cynthia L. Spires, Bradley D. Smith
Publikováno v:
Cancer Research. 80:1657-1657
Targeted fluorescent probes were used for cancer imaging and assessing tumor targeting performance in a living mouse model. Untargeted probes and targeted probes (appended with cRGDfK peptide units for integrin targeting on cancer cells) were fabrica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3576c65b2be100794c52b147edcb4f28
https://doi.org/10.1158/1538-7445.am2020-1657
https://doi.org/10.1158/1538-7445.am2020-1657
Publikováno v:
Organicbiomolecular chemistry. 16(46)
The photophysical properties of a deep-red fluorescent squaraine dye can be improved by encapsulating it within a tetralactam macrocycle. Three new tetralactams are described with different substituents (methyl, methoxy, methylenedioxy) on the macroc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3f205ae2d72309f319887f6b6a89402
https://pubmed.ncbi.nlm.nih.gov/30418456
https://pubmed.ncbi.nlm.nih.gov/30418456