Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Jane Zveiter de Moraes"'
Autor:
Rodrigo Barbosa de Aguiar, Tábata de Almeida da Silva, Bruno Andrade Costa, Marcelo Ferreira Marcondes Machado, Renata Yoshiko Yamada, Camila Braggion, Kátia Regina Perez, Marcelo Alves Silva Mori, Vitor Oliveira, Jane Zveiter de Moraes
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Single-chain variable fragments (scFvs) are small-sized artificial constructs composed of the immunoglobulin heavy and light chain variable regions connected by a peptide linker. We have previously described an anti-fibroblast growth factor
Externí odkaz:
https://doaj.org/article/c479d1dc3885419f9263069f0a30f633
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Several studies report the key role of the vascular endothelial growth factor (VEGF) signaling on angiogenesis and on tumor growth. This has led to the development of a number of VEGF-targeted agents to treat cancer patients by disrupting the tumor b
Externí odkaz:
https://doaj.org/article/8ea022d92b934db0b5e956d0829899f4
Autor:
Barbara Hamaguchi, Gabriela de Fátima da Silva Soares, Jane Zveiter de Moraes, Tauane Mathias Pereira, Juliana Harumi Osaki, Camila Braggion, Rodrigo Barbosa de Aguiar, Enzo Reina Speciale, Fernanda Beatriz Viana Cesar
Monoclonal antibody (mAb) has broad applicability in research, diagnosis, and treatment. After the introduction of hybridoma technology in 1975, the mAb market has increased dramatically, moving a large industry of more than US$ 140 billions in 2020.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2de622098929487872889a4b0dddde27
https://doi.org/10.5772/intechopen.95485
https://doi.org/10.5772/intechopen.95485
Autor:
Joana Tomomi Sumikawa, Maria Tereza dos Santos Correia, Camila Ramalho Bonturi, Rodrigo da Silva Ferreira, Manoel João Batista Castello Girão, Misako U. Sampaio, Jane Zveiter de Moraes, Maria Luiza Vilela Oliva, Fabricio Pereira Batista, Carolina M. Vicente, Sheila Siqueira Andrade, Leny Toma, Patrícia Maria Guedes Paiva, Claudia Alessandra Andrade de Paula, Thaysa Paschoalin, Yara Aparecida Lobo, Rodrigo Barbosa de Aguiar
Publikováno v:
Biochimie. 166:173-183
Formation of new blood vessels from preexisting ones, a process known as angiogenesis, is one of the limiting steps for success in treatment of ischemic disorders. Therefore, efforts to understanding and characterize new agents capable to stimulate n
Autor:
Katia Regina Perez, Bruno Andrade Costa, Jane Zveiter de Moraes, Rodrigo Barbosa de Aguiar, Vitor Oliveira, Tábata de Almeida da Silva, Camila Braggion, Renata Yoshiko Yamada, Marcelo A. Mori, Marcelo F.M. Machado
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Scientific Reports
Scientific Reports
Single-chain variable fragments (scFvs) are small-sized artificial constructs composed of the immunoglobulin heavy and light chain variable regions connected by a peptide linker. We have previously described an anti-fibroblast growth factor 2 (FGF2)
Autor:
Gabriela de Fátima da Silva Soares, Camila Braggion, Enzo Reina Speciale, Tauane Mathias Pereira, Juliana Harumi Osaki, Jane Zveiter de Moraes, Barbara Hamaguchi, Fernanda Beatriz Viana Cesar, Rodrigo Barbosa de Aguiar
Publikováno v:
Current Research in Immunology, Vol 2, Iss, Pp 32-40 (2021)
The isolation of single monoclonal antibodies (mAbs) against a given antigen was only possible with the introduction of the hybridoma technology, which is based on the fusion of specific B lymphocytes with myeloma cells. Since then, several mAbs were
Autor:
Ian W. Hamley, Lucas Rodrigues de Mello, Mehedi Reza, Janne Ruokolainen, Rodrigo Barbosa de Aguiar, Renata Y. Yamada, Emerson Rodrigo da Silva, Wendel A. Alves, Jane Zveiter de Moraes
Publikováno v:
Journal of materials chemistry. B. 8(12)
Amphiphilicity is the most critical parameter in the self-assembly of surfactant-like peptides (SLPs), regulating the way by which hydrophobic attraction holds peptides together. Its effects go beyond supramolecular assembly and may also trigger diff
Autor:
Paulo Eduardo Orlandi-Mattos, Jane Zveiter de Moraes, Luiz Juliano, Maria A. Juliano, Itabajara da Silva Vaz Junior, Rodrigo Barbosa de Aguiar, Elisaldo Luiz de Araujo Carlini
Publikováno v:
Peptides. 115
Stem bromelain [EC 3.4.22.32] is a thiol-endopeptidase and orally recommended in traditional medicine due to its analgesic activity, but the mechanisms are not known. Proenkephalin is expressed in the nervous system, but also in the gastrointestinal
Autor:
Rodrigo Barbosa de Aguiar, Jéssica de Souza Sanches, Jane Zveiter de Moraes, Carolina Bellini Parise, Roger Chammas, Juliana Mayumi Suzuki
Publikováno v:
Cancer Science
Tumors require blood supply and, to overcome this restriction, induce angiogenesis. Vascular endothelial growth factor (VEGF) plays an important role in this process, which explains the great number of antiangiogenic therapies targeting VEGF. The res
Autor:
Priscila Martins Andrade Denapoli, Bianca Ferrarini Zanetti, Adara Aurea dos Santos, Sang Won Han, Jane Zveiter de Moraes
Publikováno v:
Cancer immunology, immunotherapy : CII. 66(3)
Carcinoembryonic antigen (CEA) is expressed during embryonic life and in low level during adult life. Consequently, the CEA is recognized by the immune system as a self-antigen and thus CEA-expressing tumors are tolerated. Previously, we constructed