Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Jane Withnall"'
Autor:
Cooper Martin, Clare Murray, Iain J. Martin, Reynolds Rachel Heulwen, Eyssade Christine, Anthony Ingall, Douglas Ferguson, Andrew M. Davis, Raymond Hutchinson, Evans Richard, David Donald, Phillip Thorne, Perry Matthew, Barrie Martin, John R. Bantick, Rukhsana Tasneem Mohammed, Stephen J. Hill, Simon Guile, Lee P. Kingston, David Cheshire, Jane Withnall, David J. Wilkinson
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 16:2260-2265
A novel series of potent blockers of the monocarboxylate transporter, MCT1, is disclosed. From very potent but lipophilic lead compounds, systematic changes to all parts of the molecule, targeting reduction in log D, afforded compounds with significa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9008095be3d29fc103a2c186b3f3bb6d
https://doi.org/10.1016/j.bmcl.2006.01.024
https://doi.org/10.1016/j.bmcl.2006.01.024
Publikováno v:
The Journal of Organic Chemistry. 68:8700-8703
Heating dipolarophiles with 4-alkyl-3-hydroxy-2H-pyrazolo[4,3-c]isoquinolinium hydroxide inner salts results in [3 + 2] cycloaddition across positions 3a and 5 of the aromatic system to give the [3 + 2] cycloadducts in good yield. When the 4-alkyl su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bf7735ae494602c663e97419105319a
https://doi.org/10.1021/jo034160f
https://doi.org/10.1021/jo034160f
Autor:
Phillip A. Abbott, Roger Bonnert, Peter Cage, Steve Hill, Mark Furber, Moya Caffrey, David Donald, Andrew Cooke, Jane Withnall
Publikováno v:
Tetrahedron. 58:3185-3198
General methods are descibed for the synthesis of mesoionic derivatives of [1,2,3]triazolo[1,5-a]quinoline, [1,2,3]triazolo[1,5-a]quinazoline, [1,2,3]triazolo[1,5-a]quinoxaline and [1,2,3]triazolo[5,1-c]benzotriazine.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::676797cff63a60530329ac62f53e1a79
https://doi.org/10.1016/s0040-4020(02)00269-7
https://doi.org/10.1016/s0040-4020(02)00269-7
Autor:
Steve Hill, David Donald, Moya Caffrey, Mark Furber, Phillip A. Abbott, Roger Bonnert, Jane Withnall, Andrew Cooke, Peter Cage
Publikováno v:
ChemInform. 33
General methods are descibed for the synthesis of mesoionic derivatives of [1,2,3]triazolo[1,5-a]quinoline, [1,2,3]triazolo[1,5-a]quinazoline, [1,2,3]triazolo[1,5-a]quinoxaline and [1,2,3]triazolo[5,1-c]benzotriazine.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92d6766518f5c54d0bb07f1db8c4c842
https://doi.org/10.1002/chin.200237134
https://doi.org/10.1002/chin.200237134