Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Jane Winer"'
Publikováno v:
Experimental Cell Research. 292:11-20
Aberrant activation of the Wnt signaling pathway is a common event in human tumor progression. Wnt signaling has also been implicated in maintaining a variety of adult and embryonic stem cells by imposing a restraint to differentiation. To understand
Autor:
Franklin Peale, Constance H. Zlot, Robert Soriano, Jane Winer, Suya Yang, Gladys Ingle, Mary E. Gerritsen, P. Mickey Williams, Karen Toy, Thomas D. Wu, Aparna Draksharapu
Publikováno v:
Physiological Genomics. 10:13-20
The objective of this study was to use gene expression data from well-defined cell culture models, in combination with expression data from diagnostic samples of human diseased tissues, to identify potential therapeutic targets and markers of disease
Autor:
Belinda Cairns, H S Phillips, A. Shih, P. Williams, Wei-Qiang Gao, Robert Gerlai, Jane Winer, John W. Winslow, Natasha Shinsky, Mark Armanini
Publikováno v:
The Journal of Neuroscience. 19:9538-9549
EphA family receptor tyrosine kinases and their ephrin-A ligands are involved in patterning axonal connections during brain development, but until now a role for these molecules in the mature brain had not been elucidated. Here, we show that both the
Autor:
Jane Winer, Jeff Hooley, Jennie P. Mather, Jadine Lai, Kathleen L. King, P. Mickey Williams, Elizabeth Luis, Randy Yen
Publikováno v:
Endocrine. 5:85-93
Cardiac fibroblasts in culture produce factor(s) that induce hypertrophy of neonatal rat ventricular myocytes in vitro. As in vivo, the myocyte hypertrophy response in culture is characterized by an increase in cell size and contractile protein conte
Publikováno v:
Journal of Biological Chemistry. 269:25646-25654
The recently identified placenta growth factor (PIGF) is a member of the vascular endothelial growth factor (VEGF) family of growth factors. PIGF displays a 53% identity with the platelet-derived growth factor-like region of VEGF. By alternative spli
Publikováno v:
Journal of Biological Chemistry. 267:26031-26037
The vascular endothelial growth factor (VEGF) family encompasses four polypeptides that result from alternative splicing of mRNA. We have previously demonstrated differences in the secretion pattern of these polypeptides. Stable cell lines expressing
Publikováno v:
Proceedings of the National Academy of Sciences. 89:698-702
Medium conditioned by bovine pituitary follicular cells paradoxically inhibits the growth of adult bovine aortic endothelial (ABAE) cells at dilutions that are instead mitogenic to adrenal cortex capillary endothelial (ACCE) cells, suggesting that fo
Publikováno v:
Growth Factors. 7:53-64
Angiogenesis plays critical roles in organ development during embryonic and fetal life, wound healing and in a variety of pathological conditions. Vascular endothelial growth factor (VEGF) is a secreted growth factor specific for vascular endothelial
Publikováno v:
Molecular Endocrinology. 5:1806-1814
Vascular endothelial growth factor (VEGF) was recently identified as a secreted, direct-acting mitogen specific for vascular endothelial cells and capable of stimulating angiogenesis in vivo. Molecular cloning revealed multiple forms of VEGF, apparen
Publikováno v:
Growth Factors. 5:141-148
We examined whether cultured bovine aortic smooth muscle (ASM) cells express VEGF. RNA blot analysis of total cellular RNA derived from ASM cells demonstrates the expression of the VEGF gene. ASM cells release in the medium a VEGF-like endothelial ce