Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Jane Wilton"'
Autor:
Lidija Persic, Hennie R. Hoogenboom, Antonino Cattaneo, Jane Wilton, Andrew Bradbury, Andy Roberts
Publikováno v:
Gene. 187:9-18
Phage display is now an established method to select antibody fragments specific for a wide range of diverse antigens. In particular, isolation of human monoclonal antibodies has become a reality and for most purposes bacterial expression of the sele
Autor:
Jane K. Osbourn, John C. Earnshaw, Anne W Field, Peter T. Jones, Elaine Joy Derbyshire, John McCaffertya, Deborah Allen, Jane Wilton
Publikováno v:
Immunotechnology. 2:181-196
Background : A human single chain Fv (scFv) specific for human carcinoembryonic antigen (CEA) has been isolated from a 2.0 × 10 9 phage display library from unimmunised human donors. The dissociation constant of the scFv has been measured by surface
Publikováno v:
FEMS Microbiology Letters. 110:139-145
A gene library of Neisseria meningitidis B15 P1.16 DNA was established in lambda Zap II and clones containing DNA encoding transferrin binding protein 1 (TBP-1) identified following hybridisation with a 63-bp DNA probe based on the codon assignment f
Publikováno v:
FEMS Microbiology Letters. 107:59-66
The genes encoding transferrin-binding proteins (TBPs) 1 and 2 of Neisseria meningitidis and N. gonorrhoeae were used as model loci in a novel method of cloning (twin N-terminal polymerase chain reaction; TNT-PCR) involving amplification between the
Autor:
Sarah Helen Main, John T. Andrews, Tristan J. Vaughan, Louise A. Conroy, Rachel L. C. Handy, Liz Williams, Jane Wilton, Stephen A. Smith, I.K. Anderson, Richard D. May, Leila Du Fou
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 319(3)
The CC chemokine, eotaxin1 (CCL11) is an important regulator of eosinophil function. A marked accumulation of eosinophils in tissues has been correlated with the up-regulation of eotaxin1 expression in several diseases. The potential therapeutic valu
Publikováno v:
Expert opinion on investigational drugs. 7(5)
This was the first antibody engineering conference held by IBC Conferences in the UK, and was the European equivalent of the annual US meeting held in San Diego. The conference provided a forum for an update on progress in all aspects of antibody eng
Autor:
Jane Wilton, Marian Charles
Publikováno v:
Social Work Ideals and Practice Realities ISBN: 9780333749760
Social Work Ideals and Practice Realities
Social Work Ideals and Practice Realities
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ae82c4816ff1909330204ed3331d3d1
https://doi.org/10.1007/978-0-230-21325-8_9
https://doi.org/10.1007/978-0-230-21325-8_9
Autor:
Sarah Helen Main, Ralph Minter, Bryan M. Edwards, Stephen Ullrich, Jane Wilton, Elizabeth Williams, Gil H. Choi, Vivian R. Albert, Tristan J. Vaughan, Leila Du Fou, Steven C. Barash, Steve Ruben
Publikováno v:
Journal of molecular biology. 334(1)
It is well established that the humoral immune response can generate antibodies to many different antigens. The antibody diversity required to achieve this is believed to be substantial. However, the extent to which the immune repertoire can generate
Publikováno v:
Journal of Hospital Infection. 19:287-289
Autor:
Ray Field, Philip R. Tempest, Julia Elizabeth Thompson, Andrew James Williams, Tristan J. Vaughan, Ronald Henry Jackson, Mia Martins, Jonathan Alexander Green, Jane Wilton, Kevin Stuart Johnson, Steven Paul Ruddock, Louise Bacon, Anthony Richard Pope
Publikováno v:
Journal of immunological methods. 227(1-2)
Phage display provides a methodology for obtaining fully human antibodies directed against human transforming growth factor-beta (TGFbeta) suitable for the treatment of fibrotic disorders. The strategy employed was to isolate a human single chain Fv