Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jane Weaver-Feldhaus"'
Autor:
Russell Bell, Fernand Labrie, Jodi Mcarthur-Morrison, S.C. Snyder, Robert Kehrer, Linda Steele, Thaylon Davis, K. Nguyen, Martine Dumont, J.T. Mitchell, Alun Thomas, Teresa Janecki, Mark H. Skolnick, Lisa A. Cannon-Albright, M. Stringfellow, Chantal Samson, David H. F. Teng, Alexander Kamb, T. Hattier, Barbara L. Weber, Sofia D. Merajver, Dominique Stoppa-Lyonnet, Hiroaki Shizuya, David E. Goldgar, Marianne Schroeder, T.D. Tran, Ping Jiang, Carole Bélanger, Jorunn E. Eyfjord, Simin Berry, Jacques Simard, J.-F. Leblanc, Martine Tranchant, Steinunn Thorlacius, Qian Chen, Robert Bogden, Yi Peng, Jane Weaver-Feldhaus, Sean V. Tavtigian, Fergus J. Couch, Cheryl Frye, Johanna M. Rommens, Alexander K. C. Wong, Srikanth Jammulapati, C. Stroup, Bradley D. Swedlund, Susan L. Neuhausen, Donna M Shattuck-Eidens, Kenneth Offit, J. Swense
Publikováno v:
Nature Genetics. 12:333-337
Breast carcinoma is the most common malignancy among women in developed countries. Because family history remains the strongest single predictor of breast cancer risk, attention has focused on the role of highly penetrant, dominantly inherited genes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2ed0a2178f423da973579178b301888
https://doi.org/10.1038/ng0396-333
https://doi.org/10.1038/ng0396-333
Autor:
Laurence Meyer, Marguerite Jost, Nelleke A. Gruis, Jane Weaver-Feldhaus, Lisa A. Cannon-Albright, Mark H. Skolnick, Susan L. Neuhausen, Kim Nyguen, Cathryn M. Lewis, Alexander Kamb, David E. Goldgar, T.D. Tran, John J. Zone, David E. Anderson
Publikováno v:
Genomics. 23:265-268
A familial melanoma susceptibility locus (MLM) was identified on the short arm of chromosome 9 in a set of Utah and Texas kindreds. Subsequent confirmation was reported for a set of 26 Australian kindreds, a set of 7 Dutch kindreds, and a set of 13 N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a550469c375dc76cf027b953004c5008
https://doi.org/10.1006/geno.1994.1491
https://doi.org/10.1006/geno.1994.1491
Autor:
Wei Ding, John J. Zone, Thanh Tran, David E. Goldgar, Lisa A. Cannon-Albright, Jane Weaver-Feldhaus, Laurence Meyer, Qingyun Liu, Yoshio Miki, Robert MacLennan, P. Youl, Nicholas G. Martin, David E. Anderson, Mark H. Skolnick, Wilma Bergman, Joanne F. Aitken, Charles E. Hussey, Rune R. Frants, Nelleke A. Gruis, Adèle C. Green, Alexander Kamb, Melody McClure, Rosalind A. Eeles, Donna M Shattuck-Eidens
Publikováno v:
Nature Genetics. 8:22-26
A locus for familial melanoma, MLM, has been mapped within the same interval on chromosome 9p21 as the gene for a putative cell cycle regulator, p16INK4 (CDKN2) MTS1. This gene is homozygously deleted from many tumour cell lines including melanomas,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75de525a1d6de9dda14c7d0a448264bf
https://doi.org/10.1038/ng0994-22
https://doi.org/10.1038/ng0994-22
Autor:
Sean V. Tavtigian, Jane Weaver-Feldhaus, Keith D Harshman, Bruce E. Johnson, Alexander Kamb, Qingyun Liu, Mark H. Skolnick, Nelleke A. Gruis, Elisabeth Stockert, Rufus S. Day
Publikováno v:
Science. 264:436-440
A putative tumor suppressor locus on the short arm of human chromosome 9 has been localized to a region of less than 40 kilobases by means of homozygous deletions in melanoma cell lines. This region contained a gene, Multiple Tumor Suppressor 1 (MTS1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e58bcad11c36232f8890012d1b22bba
https://doi.org/10.1126/science.8153634
https://doi.org/10.1126/science.8153634
Autor:
Jane Weaver-Feldhaus, Alexander Kamb, Rune R. Frants, Wilma Bergman, Nelleke A. Gruis, Prins De, Lodewijk A. Sandkuijl, van der Velden Pa
Publikováno v:
Nature Genetics. 10:351-353
The p16 gene (CDKN2) which is localized on chromosome 9p21, is deleted in a significant number of sporadic cancers1–3. Moreover, germline mutations identified in some melanoma-prone kindreds4,5 last year suggested that CDKN2 is identical to the 9p2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d64ecaa4f32ea648fc8cbd573b4905d
https://doi.org/10.1038/ng0795-351
https://doi.org/10.1038/ng0795-351
Autor:
Jane Weaver-Feldhaus, Srikanth Jammulapati, Donna Shattuck, Alun Thomas, Charles H. Hensel, Robyn Riley, Richard E. Gress, Victor Abkevich, Alexander Gutin, Deanna L. Russell, Tess Macalma, Mike Francis, Steven C. Hunt, Xiankang Hong, Maria Matthews Richards, Chris Neff, Steven Stone, Ted D. Adams, Thanh Tran, Georges C. Frech
Publikováno v:
Human genetics. 109(3)
Several linkage studies have hinted at the existence of an obesity predisposition locus on chromosome 20, but none of these studies has produced conclusive results. Therefore, we analyzed 48 genetic markers on chromosome 20 for linkage to severe obes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d65d4e7562152eab81359654bc5b9679
https://pubmed.ncbi.nlm.nih.gov/11702208
https://pubmed.ncbi.nlm.nih.gov/11702208
Autor:
Charles Cochran, Keith D Harshman, Wei Ding, Yoshio Miki, L. Michelle Bennett, Peter Söderkvist, Alexander Kamb, Sean V. Tavtigian, Zahra Gholami, Qingyun Liu, Suresh C. Jhanwar, Dennis G. Ballinger, Jeff Swensen, Donna M Shattuck-Eidens, Roger W. Wiseman, Astrid Haugen-Strano, Cheryl Frye, P. Andrew Futreal, Mark H. Skolnick, J. Cari Barrett, Jane Weaver-Feldhaus, Lori A. Terry, Jeffrey R. Marks, J. Dirk Iglehart, Andrew Berchuck, Melody McClure, Ken Eddington
Publikováno v:
Science (New York, N.Y.). 266(5182)
Loss of heterozygosity data from familial tumors suggest that BRCA1, a gene that confers susceptibility to ovarian and early-onset breast cancer, encodes a tumor suppressor. The BRCA1 region is also subject to allelic loss in sporadic breast and ovar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52820dc29c5f94f2cbe151f0ced87113
https://pubmed.ncbi.nlm.nih.gov/7939630
https://pubmed.ncbi.nlm.nih.gov/7939630
Autor:
D Le Paslier, Elisabeth Stockert, Mark H. Skolnick, Jane Weaver-Feldhaus, Nelleke A. Gruis, Alexander Kamb, Susan L. Neuhausen
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 91(16)
The p21 region of human chromosome 9 is thought to contain a gene (MLM) involved in genetic susceptibility to melanoma and a gene or genes that influence progression of certain other tumors. Genomic clones that span a large region in 9p21 surrounding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc68f06350241742d8b56152acc9756e
https://pubmed.ncbi.nlm.nih.gov/8052620
https://pubmed.ncbi.nlm.nih.gov/8052620