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pro vyhledávání: '"Jane Trussler"'
Autor:
Laureen Jacquet, Emma Stephenson, Robert Collins, Heema Patel, Jane Trussler, Roaa Al‐Bedaery, Pamela Renwick, Caroline Ogilvie, Robert Vaughan, Dusko Ilic
Publikováno v:
EMBO Molecular Medicine, Vol 5, Iss 1, Pp 10-17 (2012)
Abstract Here, we describe a pre‐derivation embryo haplotyping strategy that we developed in order to maximize the efficiency and minimize the costs of establishing banks of clinical grade hESC lines in which human leukocyte antigen (HLA) haplotype
Externí odkaz:
https://doaj.org/article/ea9bd21c1a0045e0a314854604b56604
Publikováno v:
Reproductive BioMedicine Online. 20:470-476
Preimplantation genetic diagnosis using whole genome amplification and a haplotyping approach (PGH) was first described in 2006 and suggested as an efficient alternative to single-cell PCR for monogenic disorders. DNA from single cells was amplified
Autor:
R. Collins, Caroline Mackie Ogilvie, Jane Trussler, Roaa Al-Bedaery, Emma Stephenson, Dusko Ilic, Robert Vaughan, Pamela Renwick, Heema Patel, Laureen Jacquet
Publikováno v:
EMBO Molecular Medicine
Here, we describe a pre-derivation embryo haplotyping strategy that we developed in order to maximize the efficiency and minimize the costs of establishing banks of clinical grade hESC lines in which human leukocyte antigen (HLA) haplotypes match a s