Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jane Theaker"'
Autor:
Luis Veiga Nobre, Celia Colomina Basanta, Salvatore Federico Pedicona, Arran David Dokal, Andrea Arruda, Ryan Smith, Calum Greenhalgh, Francesca Patella, Pedro Maria Casado-Izquierdo, Bela Wrench, Jane Theaker, Andrew Thompson, Mark D. Minden, John G. Gribben, David James Britton, Pedro Rodriguez Cutillas
Publikováno v:
Molecular Cancer Therapeutics. 20:LBA013-LBA013
Background: Midostaurin (mido) is approved for treatment of FLT3 mutant-positive (FLT3+) acute myeloid leukemia (AML). However, FLT3 mutation is not the only determinant of mido sensitivity. Here we report phosphoprotein signatures which predict resp
Autor:
Jane Theaker, Andrea Arruda, John G. Gribben, Andrew Hugin Thompson, Ryan Smith, Luis Miguel Veiga Veiga Nobre, Pedro R. Cutillas, Arran Dokal, Francesca Patella, Salvatore Federico Pedicona, Mark D. Minden, Bela Wrench, Calum Greenhalgh, Pedro Casado-Izquierdo, David Britton
Publikováno v:
Blood. 138:3462-3462
Background: Midostaurin is approved for FLT3 mutant-positive (FLT3+) acute myeloid leukemia (AML), however efficacy has also been observed in a subpopulation of FLT3 mutant-negative AML, suggesting that FLT3 mutation is not the only determinant confe
Autor:
Jane Theaker, Christopher T Williams, Mauricio Espinel, Evelin Donis, Luis E. Cuevas, Leticia del Carmen Castillo Signor, Thomas Edwards, Clément Larcher, Emily R. Adams
Publikováno v:
Diagnostic Microbiology and Infectious Disease
Chikungunya was introduced into the Americas in 2015 causing a pandemic across the continent. Testing during the acute phase of infection relies on qRT-PCR, but available assays have a number of limitations. A qRT-PCR assay specific to the chikunguny
Autor:
Mark D. Minden, Pedro R. Cutillas, John G. Gribben, Ryan P. Smith, Calum Greenhalgh, Francesca Patella, Jane Theaker, Arran Dokal, David Britton, Andrea Arruda, Andrew B Thompson, Pedro Casado-Izquierdo, Bela Wrench
Publikováno v:
Journal of Clinical Oncology. 39:7019-7019
7019 Background: Midostaurin is approved for FLT3 mutant-positive (FLT3+) acute myeloid leukemia (AML), however efficacy has also been observed in a subpopulation of FLT3 mutant-negative AML, suggesting that FLT3 mutation is not the only determinant
Autor:
Stephen Little, Clive R. Newton, David Mark Whitcombe, Richard M. Ferrie, Jane Theaker, Jannine Brownie, Susan G. Shawcross
Publikováno v:
Nucleic Acids Research. 25:3235-3241
We attempted to produce primer-dimers (PDs) from a variety of primers with differing types and extents of complementarity. Where PDs were produced they were cloned and sequenced. We were unable to produce detectable PDs either with individual primers
Publikováno v:
Nature biotechnology. 17(8)
Molecular diagnostics is progressing from low-throughput, heterogeneous, mostly manual technologies to higher throughput, closed-tube, and automated methods. Fluorescence is the favored signaling technology for such assays, and a number of techniques