Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Jane Reese Koc"'
Autor:
Jiasheng Wang, Farhad Sanati, Amin Firoozmand, Pingfu Fu, Merle Kolk, Jane Reese-Koc, Marcos de Lima, Kirsten Boughan, Brenda Cooper, Paolo Caimi, Molly Gallogly, Folashade Otegbeye, Benjamin Tomlinson, Leland Metheny
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Cord blood (CB) is a valuable graft source for patients undergoing allogeneic hematopoietic cell transplant (HCT) who lack human leukocyte antigen (HLA)-matched donors. However, single-unit CB-HCT is limited by the insufficient cell dose and slow eng
Externí odkaz:
https://doaj.org/article/c65d5f781c184501a6d5354ec16c28bc
Autor:
Maya Breitman, Tracey L. Bonfield, Arnold I. Caplan, Hillard M. Lazarus, Maricela Haghiac, Susan LaSalvia, Jane Reese‐Koc, Nora G. Singer
Publikováno v:
ACR Open Rheumatology, Vol 4, Iss 2, Pp 152-160 (2022)
Objective Seropositive rheumatoid arthritis (RA) is a chronic autoimmune disease that is rarely “cured.” Human mesenchymal stem cells (hMSCs) are known to reduce inflammation and restore immune homeostasis. However, methods for predicting therape
Externí odkaz:
https://doaj.org/article/a7bd0d1395f0457a964cc475331d0a16
Autor:
Michael Maschan, Paolo F. Caimi, Jane Reese-Koc, Gabriela Pacheco Sanchez, Ashish A. Sharma, Olga Molostova, Larisa Shelikhova, Dmitriy Pershin, Alexey Stepanov, Yakov Muzalevskii, Vinicius G. Suzart, Folashade Otegbeye, David Wald, Ying Xiong, Darong Wu, Adam Knight, Ibe Oparaocha, Beatrix Ferencz, Andre Roy, Andrew Worden, Winfried Kruger, Michael Kadan, Dina Schneider, Rimas Orentas, Rafick-Pierre Sekaly, Marcos de Lima, Boro Dropulić
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Strategies to address the challenges associated with product manufacturing can improve chimeric antigen receptor (CAR) cell–based therapeutics. Here the authors report the results of two clinical trials in patients with B-cell malignancies, showing
Externí odkaz:
https://doaj.org/article/1879f85252424882a5288bc97bee3406
Autor:
Ke Zeng, Meixian Huang, Mi-Ae Lyu, Joseph D. Khoury, Sairah Ahmed, Krina K. Patel, Boro Dropulić, Jane Reese-Koc, Paolo F. Caimi, Tara Sadeghi, Marcos de Lima, Christopher R. Flowers, Simrit Parmar
Publikováno v:
Cells, Vol 12, Iss 14, p 1880 (2023)
With greater accessibility and an increased number of patients being treated with CAR T cell therapy, real-world toxicity continues to remain a significant challenge to its widespread adoption. We have previously shown that allogeneic umbilical cord
Externí odkaz:
https://doaj.org/article/d9710af70c644334bc7a67911e854f02
Autor:
Tracey L. Bonfield, Morgan T. Sutton, David R. Fletcher, Jane Reese-Koc, Erica A. Roesch, Hillard M. Lazarus, James F. Chmiel, Arnold I. Caplan
Publikováno v:
Pharmaceuticals, Vol 16, Iss 2, p 220 (2023)
Human Mesenchymal Stem Cell (hMSC) immunotherapy has been shown to provide both anti-inflammatory and anti-microbial effectiveness in a variety of diseases. The clinical potency of hMSCs is based upon an initial direct hMSC effect on the pro-inflamma
Externí odkaz:
https://doaj.org/article/2cce549d1cb548528d249719d866e57c
Autor:
Paolo F. Caimi, Gabriela Pacheco Sanchez, Ashish Sharma, Folashade Otegbeye, Nausheen Ahmed, Patricio Rojas, Seema Patel, Sarah Kleinsorge Block, Jennifer Schiavone, Kayla Zamborsky, Kirsten Boughan, Antoinette Hillian, Jane Reese-Koc, Mikhail Maschan, Boro Dropulic, Rafick-Pierre Sekaly, Marcos de Lima
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Anti-CD19 chimeric antigen receptor T (CAR-T) cells have demonstrated activity against relapsed/refractory lymphomas. Cytokine release syndrome (CRS) and immune effector cell – associated neurotoxicity syndrome (ICANS) are well-known complications.
Externí odkaz:
https://doaj.org/article/b8b7b782c28b4871b38e4eeaec8b2a0f
Autor:
Maricela Haghiac, Tracey L. Bonfield, Hillard M. Lazarus, Jane Reese-Koc, Arnold I. Caplan, Susan LaSalvia, Maya Breitman, Nora G. Singer
Publikováno v:
ACR Open Rheumatology, Vol 4, Iss 2, Pp 152-160 (2022)
Objective Seropositive rheumatoid arthritis (RA) is a chronic autoimmune disease that is rarely "cured." Human mesenchymal stem cells (hMSCs) are known to reduce inflammation and restore immune homeostasis. However, methods for predicting therapeutic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1822010ac8ad089d6cf13fb372b628da
https://doaj.org/article/a7bd0d1395f0457a964cc475331d0a16
https://doaj.org/article/a7bd0d1395f0457a964cc475331d0a16
Autor:
Jane Reese-Koc, Timothy O’Brien, Paolo Caimi, Patricio Rojas, Brenda W. Cooper, Fahrettin Covut, Merle Kolk, Leland Metheny, Ehsan Malek, Marcos de Lima, Nausheen Ahmed, Lucy Li
Publikováno v:
Bone Marrow Transplantation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83eeef82943b3ba0c5872fe3c51af3f8
https://doi.org/10.1038/s41409-021-01223-y
https://doi.org/10.1038/s41409-021-01223-y
Autor:
Folashade Otegbeye, Brenda Cooper, Paolo Caimi, Kayla Zamborsky, Jane Reese-Koc, Antoinette Hillian, Yeritza Hernandez-Collazo, Grace Lee, Kirsten Boughan, Benjamin Tomlinson, Molly Gallogly, Leland Metheny, David Bajor, Jennifer Selfridge, Joel Saltzman, Hillard Lazarus, Marcos de Lima, David Wald
Publikováno v:
Transplant Cell Ther
The administration of allogeneic natural killer (NK) cells following a lymphodepleting chemotherapy regimen is emerging as a well-tolerated therapeutic approach in the management of various malignancies. Contrary to the expected complications of allo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae23f10c89ac567aad61c2d1e8d06686
https://pubmed.ncbi.nlm.nih.gov/35172204
https://pubmed.ncbi.nlm.nih.gov/35172204
Autor:
Nausheen Ahmed, Marcos de Lima, Sarah Kleinsorge Block, Folashade Otegbeye, Patricio Rojas, Jane Reese-Koc, Seema Patel, Boro Dropulic, Ashish Sharma, Kirsten M Boughan, Jennifer Schiavone, Paolo Caimi, Gabriela Pacheco Sanchez, Antoinette Hillian, M.A. Maschan, Rafick-Pierre Sekaly, Kayla Zamborsky
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology
Frontiers in Immunology
Anti-CD19 chimeric antigen receptor T (CAR-T) cells have demonstrated activity against relapsed/refractory lymphomas. Cytokine release syndrome (CRS) and immune effector cell – associated neurotoxicity syndrome (ICANS) are well-known complications.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::647f1575b2c38ac5866b33b74201e962
https://www.frontiersin.org/articles/10.3389/fimmu.2021.745320/full
https://www.frontiersin.org/articles/10.3389/fimmu.2021.745320/full