Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Jane R. Deayton"'
Publikováno v:
International Journal of STD & AIDS. 33:1013-1017
Background HIV-2 is rare in the UK. Many UK centres therefore only treat small numbers of people and there are few clinical trials to guide treatment. The British HIV Association (BHIVA) 2010 guidelines for management of HIV-2 formed the basis for th
Autor:
Chipo Berejena, Diana M. Gibb, Naheed Choudhry, Ethan K. Gough, Nigel Klein, Amee R. Manges, Joseph Lutaakome, Godfrey Pimundu, Louise Terry, Andrew J. Prendergast, A. Sarah Walker, Thaddeus J. Edens, Yusuf Karmali, Kuda Mutasa, Hyun Min Geum, Claire D. Bourke, Moira J. Spyer, Alexander J. Szubert, Claire Pardieu, Magdalena Glass, Adeodata Kekitiinwa, Victor Musiime, Jane R. Deayton, Annie Shonhai, Mutsa Bwakura-Dangarembizi, Lucas Baumard
Publikováno v:
Science Translational Medicine. 11(486)
Long-term cotrimoxazole prophylaxis reduces mortality and morbidity in HIV infection but the mechanisms underlying these sustained clinical benefits are unclear. Here we investigate the impact of cotrimoxazole on systemic inflammation, an independent
Autor:
Are Isaksen, David F. Bibby, Chloe Orkin, Andrew J. Stagg, Áine McKnight, Jane Anderson, Katherine C. Groves, Jane R. Deayton, Duncan A. Clark
Publikováno v:
JAIDS Journal of Acquired Immune Deficiency Syndromes. 61:407-416
The mechanism of CD4 T-cell decline in HIV-1 infection is unclear, but the association with plasma viral RNA load suggests viral replication is involved. Indeed, viremic controller patients with low viral RNA loads typically maintain high CD4 T-cell
Autor:
Robert Colebunders, Marc Vekemans, Jean Ruelle, Kevin Peterson, Jane R. Deayton, Frederick P Siegal
Publikováno v:
Antiviral therapy
We describe five patients with HIV-2 infection (four antiretroviral-experienced and one antiretroviral-naive) treated with a regimen containing raltegravir. All responded to treatment as demonstrated by viral load and CD4+ T-cell count monitoring. Ou
Autor:
Jane R. Deayton, John W. Thorpe
Publikováno v:
Medicine. 37:352-356
HIV is a treatable condition and the physician should be alert to its varied neurological manifestations at all stages of the disease. Seroconversion can be associated with Guillain–Barre syndrome with characteristic cerebrospinal fluid changes. Tu
Publikováno v:
International Journal of STD & AIDS. 16:505-509
The objective of this study was (1) to estimate the prevalence of recalcitrant Trichomonas vaginalis (TV) infection in a UK genitourinary medicine clinic; (2) to use a case series and literature review to suggest an algorithm for management of recalc
Autor:
Larsson-Sciard El, Vincent C. Emery, Brian Gazzard, F. Gotch, Peter Hayes, S. Worrell, Jane R. Deayton
Publikováno v:
HIV Medicine. 2:11-19
1Department of Immunology and2The Kobler Centre, Chelsea and Westminster Hospital, and3Royal Free Hospital and University College Medical School, London, UK Objectives To evaluate whether successful, long-term immune reconstitution in vivo can be ach
Autor:
P Wilson, E.F. Bowen, Margaret A. Johnson, M. Grzywacz, Vincent C. Emery, Jane R. Deayton, Paul D. Griffiths
Publikováno v:
Journal of Medical Virology. 59:323-328
Reactivation of cytomegalovirus (CMV) following immunosuppression may result in the development of CMV disease and is associated with an increased risk of death. CMV viraemia detected by the polymerase chain reaction (PCR) precedes CMV disease in HIV
Autor:
Vincent C. Emery, Margaret Johnson, P Wilson, Paul D. Griffiths, Amanda Mocroft, Jane R Deayton
Publikováno v:
AIDS. 13:1203-1206
Objective: To determine the effect of highly active antiretroviral therapy (HAART) on cytomegalovirus (CMV) viraemia and retinitis in patients at high risk of disease.Design: Sixteen patients with CMV viraemia, but no evidence of end organ disease at
Autor:
Paul D. Griffiths, Gillian S. Clewley, Margaret Johnson, James E. McLaughlin, Christine A. Lee, Amanda Mocroft, Caroline A. Sabin, Jane R. Deayton
Publikováno v:
Journal of Medical Virology. 58:280-285
Adenoviruses have been described as a cause of diarrhoea in patients infected with the human immunodeficiency virus (HIV). The prevalence of adenoviruses was studied in all HIV-positive patients presenting with diarrhoea at the Royal Free Hospital in