Zobrazeno 1 - 10
of 129
pro vyhledávání: '"Jane R, Hanrahan"'
Autor:
I Gusti Md Gde Surya C. Trapika, Xin Tracy Liu, Long Hoa Chung, Felcia Lai, Chanlu Xie, Yang Zhao, Shaohui Cui, Jinbiao Chen, Collin Tran, Qian Wang, Shubiao Zhang, Anthony S. Don, George Qian Li, Jane R. Hanrahan, Yanfei Qi
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Prostate cancer is the second most prevalent malignancy worldwide. In the early stages, the development of prostate cancer is dependent on androgens. Over time with androgen deprivation therapy, 20% of prostate cancers progress to a castration-resist
Externí odkaz:
https://doaj.org/article/9492847f85534f5abe82d4780ead5644
Publikováno v:
Molecules, Vol 27, Iss 11, p 3462 (2022)
In 1789, the Annonaceae family was catalogued by de Jussieu. It encompasses tropical and subtropical plants which are widespread in distribution across various continents such as Asia, South and Central America, Australia and Africa. The genus of Ann
Externí odkaz:
https://doaj.org/article/45776ed2775744e5a6b601135c9fe7ec
Publikováno v:
Life, Vol 12, Iss 1, p 127 (2022)
GABAϱ receptors are distinctive GABAergic receptors from other ionotropic GABAA and metabotropic GABAB receptors in their pharmacological, biochemical, and electrophysiological properties. Although GABA-ϱ1 receptors are the most studied in this sub
Externí odkaz:
https://doaj.org/article/82c490bee08e406dbf3e80d37f0cfc48
Background: Annona muricata, also known as graviola, soursop and guanabana is a herbal product used by people living with cancer. Anecdotal clinical evidence suggests this herb has potential anti-cancer activity. There are numerous pre-clinical studi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d872533dfc5ae1bbb79190dfb20e7c7e
https://doi.org/10.21203/rs.3.rs-2325093/v1
https://doi.org/10.21203/rs.3.rs-2325093/v1
Autor:
Petra S. van Nieuwenhuijzen, Kim Parker, Vivian Liao, Josh Houlton, Hye-Lim Kim, Graham A. R. Johnston, Jane R. Hanrahan, Mary Chebib, Andrew N. Clarkson
Publikováno v:
Brain Sciences, Vol 11, Iss 3, p 315 (2021)
Ischemic stroke remains a leading cause of disability worldwide, with limited treatment options available. This study investigates GABAC receptors as novel pharmacological targets for stroke recovery. The expression of ρ1 and ρ2 mRNA in mice were d
Externí odkaz:
https://doaj.org/article/3640c36cb0b343eb8f7421cca0d8369e
The Phytochemical Constituents and Pharmacological Activities of Annona atemoya: A Systematic Review
Publikováno v:
Pharmaceuticals, Vol 13, Iss 10, p 269 (2020)
Annona atemoya also known as the custard apple is a hybrid between two Annonaceae species: Cherimoya (Annona cherimola) and the sugar apple (Annona squamosa). It is widely cultivated in tropical and subtropical continents including north and south Am
Externí odkaz:
https://doaj.org/article/846d068a4bd14d0e813d875c6ba10c54
Autor:
Bryson A. Hawkins, Felcia Lai, Esteban Cruz, Paul W. Groundwater, David E. Hibbs, Jane R. Hanrahan
Publikováno v:
Biologics, Biosimilars, and Biobetters
Autor:
Moawiah M Naffaa, Nathan Absalom, V Raja Solomon, Mary Chebib, David E Hibbs, Jane R Hanrahan
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0156618 (2016)
The loop C hydrophilic residue, threonine 244 lines the orthosteric binding site of ρ1 GABAC receptors was studied by point mutation into serine, alanine and cysteine, and tested with GABA, some representative partial agonists and antagonists. Thr24
Externí odkaz:
https://doaj.org/article/fd5f5e3e346742f6af151a31892c987b
Autor:
Anthony S. Don, Shubiao Zhang, Xin Tracy Liu, Yang Zhao, Chanlu Xie, Felcia Lai, Long Hoa Chung, Yanfei Qi, I Gusti Md Gde Surya C Trapika, Jinbiao Chen, Collin Tran, George Q. Li, Qian Wang, Shaohui Cui, Jane R. Hanrahan
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Frontiers in Oncology
Frontiers in Oncology
Prostate cancer is the second most prevalent malignancy worldwide. In the early stages, the development of prostate cancer is dependent on androgens. Over time with androgen deprivation therapy, 20% of prostate cancers progress to a castration-resist
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0141359 (2015)
2'-Methoxy-6-methylflavone (2'MeO6MF) is an anxiolytic flavonoid which has been shown to display GABAA receptor (GABAAR) β2/3-subunit selectivity, a pharmacological profile similar to that of the general anaesthetic etomidate. Electrophysiological s
Externí odkaz:
https://doaj.org/article/b5f5a49c950e4e74b1671a4fa00d32f1