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Autor:
Jane Odhiambo Mumma, Juliet S. Chhay, Jana S. Eaton, Kerry L. Ross, Karen Newell-Litwa, Judith L. Fridovich-Keil
Publikováno v:
Molecular Genetics and Metabolism. 93:160-171
Galactose is metabolized in humans and other species by the three-enzyme Leloir pathway comprised of galactokinase (GALK), galactose 1-P uridylyltransferase (GALT), and UDP-galactose 4′-epimerase (GALE). Impairment of GALT or GALE in humans results