Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Jane Nikles"'
Autor:
Katrina Williams, Peter J Anderson, James M McGree, Katrina Harris, Alison Crichton, Jane Nikles
Publikováno v:
BMJ Open, Vol 14, Iss 4 (2024)
Introduction Fetal alcohol spectrum disorder (FASD) is a neurodevelopmental disorder caused by alcohol exposure during pregnancy. FASD is associated with neurodevelopmental deviations, and 50%–94% of children with FASD meet the Diagnostic and Stati
Externí odkaz:
https://doaj.org/article/477659eb29564efa92be15362d6483df
Publikováno v:
Contemporary Clinical Trials Communications, Vol 24, Iss , Pp 100852- (2021)
Background: Evidence-based management of neuropathic pain is commonly ineffective due to the large variability in response between cases. Patients often have to trial several drugs before finding one that provides adequate relief, leading to increase
Externí odkaz:
https://doaj.org/article/881aa829a75844ebb43f2665f1c460fd
Autor:
Jane Nikles, Patrick Onghena, Johan W.S. Vlaeyen, Rikard K. Wicksell, Laura E. Simons, James M. McGree, Suzanne McDonald
Publikováno v:
Contemporary Clinical Trials Communications, Vol 23, Iss , Pp 100826- (2021)
In this article we briefly examine the unique features of Single-Case Designs (SCDs) (studies in a single participant), their history and current trends, and real-world clinical applications. The International Collaborative Network for N-of-1 Trials
Externí odkaz:
https://doaj.org/article/a3b91a727f1348a49009824f1b66ce97
Publikováno v:
BMC Medical Research Methodology, Vol 19, Iss 1, Pp 1-12 (2019)
Abstract Background Locally produced generic drugs offer a cost–effective alternative to imported drugs to treat patients in Ethiopia. However, due to a lack of bioequivalence testing, additional assurance tests are needed to build trust in cheaper
Externí odkaz:
https://doaj.org/article/5a31cb8d3f634d5ea84285f4f3688b1e
Publikováno v:
Frontiers in Computer Science, Vol 2 (2021)
Externí odkaz:
https://doaj.org/article/95e416efdaf24e8eaa8cd3a0187c851a
Autor:
Jaclyn Edelson, Josh Byrnes, Geoffrey Mitchell, Helen Heussler, Megdelawit Melaku, Jane Nikles
Publikováno v:
Contemporary Clinical Trials Communications, Vol 17, Iss , Pp - (2020)
Background: Children with ADHD and sleep problems have more caregiver deficits and decreased school attendance than children with ADHD but without a sleep problem. We conducted an N-of-1 trial of melatonin for children with ADHD on stimulants. As a f
Externí odkaz:
https://doaj.org/article/80fd2bf68da0418780ea6489d8673e82
Autor:
Kelly M. Clanchy, Sean M. Tweedy, Robyn L. Tate, Michele Sterling, Melissa A. Day, Jane Nikles, Carrie Ritchie
Publikováno v:
Contemporary Clinical Trials Communications, Vol 16, Iss , Pp - (2019)
Half of individuals with a whiplash injury experience ongoing pain and disability. Many are insufficiently active for good health, increasing their risk of preventable morbidity and mortality, and compounding the effects of the whiplash injury. This
Externí odkaz:
https://doaj.org/article/fc064208a8484f669bfb9bcfa3258464
Publikováno v:
BMC Health Services Research, Vol 18, Iss 1, Pp 1-10 (2018)
Abstract Background Because of their cost, the use of locally produced, bioequivalent, generic drugs is universally recommended. In Ethiopia. while the government is committed to raising the market share and use of locally produced drugs, the process
Externí odkaz:
https://doaj.org/article/c6faed8d5c2f464d8cb9c97b9d8c400f
Publikováno v:
Trials, Vol 19, Iss 1, Pp 1-10 (2018)
Abstract Background N-of-1 trials have a potential role in promoting patient-centered medicine in developing countries. However, there is limited academic literature regarding the use of N-of-1 trials in the clinical care of patients in resource-poor
Externí odkaz:
https://doaj.org/article/31eea759eab446ae90117b26fb04ed5e
Publikováno v:
International Journal for Equity in Health, Vol 17, Iss 1, Pp 1-11 (2018)
Abstract Background Clinical trials for identification of efficient and effective new diagnostic and treatment modalities are needed to address disproportionately high burden of communicable (e.g., HIV/AIDS, tuberculosis, and malaria) and non-communi
Externí odkaz:
https://doaj.org/article/0a41dcc3afca4bbd9f83b73f5f738285